- Caspase-1
- Caspase-3
- Caspase-8
- Caspase-9
- Caspase-4
- Capase-7
- Caspase-2
- Caspase-5
- Caspase-6
- Caspase-10
- Caspase-7
Caspase-5 抑制剂
| 目录号 | 产品名 | 产品描述 | Selective / Pan | IC50 / Ki |
|---|---|---|---|---|
| S7901 | Ac-DEVD-CHO | Ac-DEVD-CHO (Caspase-3 Inhibitor I, N-Ac-Asp-Glu-Val-Asp-CHO) is a potent aldehyde inhibitor of Group II caspases with Ki values of 0.2 nM and 0.3 nM for for caspase-3 and caspase-7, respectively. Weak inhibition for caspase-2. | Pan | caspase-5, Ki: 205 nM |
| S9817 | Ac-FLTD-CMK | Ac-FLTD-CMK is a specific inhibitor for inflammatory caspases. Ac-FLTD-CMK inhibits gasdermin D (GSDMD) cleavage by caspases-1, -4, -5, and -11 in vitro. Ac-FLTD-CMK is effective against caspases-1, caspases-4 and caspases-5 with IC50 of 46.7 nM, 1.49 μM and 329 nM, respectively. | Pan | caspases-5, IC50: 329 nM |
