ET-A
ET-B

ET-B 拮抗剂

目录号	产品名	产品描述	Selective / Pan	IC50 / Ki
S3051	Bosentan Hydrate	Bosentan (Ro 47-0203) is an endothelin (ET) receptor antagonist for ET-A and ET-B with K_i of 4.7 nM and 95 nM, respectively.	Pan	ET-B, Ki: 95 nM
S8051	Macitentan (ACT 064992)	Macitentan (ACT 064992) is an orally active, non-peptide, dual ETA/ETB (endothelin) receptor antagonist with IC50 of 0.5 nM/391 nM.	Pan	ET-B, IC50: 391 nM