| S5911 |
Bictegravir |
Bictegravir (GS-9883) is a novel, potent, once-daily, unboosted inhibitor of HIV-1 integrase. |
Selective |
|
| S0235 |
Lavendustin B |
Lavendustin B inhibits HIV-1 integrase (IN) interaction with its cognate cellular cofactor lens epithelium-derived growth factor (LEDGF/p75). Lavendustin B is an inhibitor of Tyrosine Kinase and also a competitive inhibitor of glucose transporter 1 (Glut1). |
Selective |
|
| S1366 |
BMS-707035 |
BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2. |
Selective |
HIV-I integrase, IC50: 15 nM |
| S2001 |
Elvitegravir (JTK-303) |
Elvitegravir (GS-9137,JTK-303,D06677) is an HIV integrase inhibitor for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM in cell-free assays, respectively. |
Pan |
HIV-1 IIIB, IC50: 0.7 nM |
