- PRMT5
- PRMT4
- PRMT6
- PRMT1
- PRMT8
- PRMT3
PRMT6 选择性抑制剂
| 目录号 | 产品名 | 产品描述 | Selective / Pan | IC50 / Ki |
|---|---|---|---|---|
| S7820 | EPZ020411 2HCl | EPZ020411 is a potent and selective small molecule PRMT6 inhibitor with an IC50 of 10 nM. | Selective | PRMT6, IC50: 10 nM |
| S8112 | MS023 | MS023 is a potent, selective, and cell-active Type I PRMT inhibitor with IC50 of 30 nM, 119 nM, 83 nM, 4 nM, and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8, respectively. | Pan | PRMT6, IC50: 4 nM |
| s8147 | MS049 | MS049 is a potent and selective inhibitor of PRMT4 and PRMT6 with IC50s of 34 nM and 43 nM, respectively. | Pan | PRMT6, IC50: 43 nM |
| S8858 | GSK3368715 3HCl | GSK3368715 3HCl is a potent inhibitor of type I protein arginine methyltransferases (PRMT) that inhibits PRMT1, 3, 4, 6 and 8 with Kiapp vaules ranging from 1.5 to 81 nM. | Pan |
