| S0007 |
RO 5028442 (RG7713) |
RO 5028442 (RG7713) is a highly potent and selective Brain-Penetrant Vasopressin 1a (V1a) receptor antagonist with Kis of 1 nM for hV1a and 39 nM for mV1a. |
Selective |
hV1a, Ki: 1 nM; mV1a, Ki: 39 nM |
| S2920 |
Mozavaptan |
Mozavaptan (OPC-31260) is a novel competitive vasopressin receptor antagonist for both V1 and V2 receptors with IC50 of 1.2 μM and 14 nM, respectively. |
Pan |
Vasopressin receptor 1, IC50: 1.2 μM |
| S2116 |
Conivaptan HCl |
Conivaptan HCl(YM 087) is an orally active, non-peptide, vasopressin V1A and V2 receptor antagonist, used in the treatment of euvolemic and hypervolemic hyponatremia. |
Pan |
|
