Menin-MLL interaction
WDR5-MLL interaction

WDR5-MLL-interaction 抑制剂 | 拮抗剂

目录号	产品名	产品描述	Selective / Pan	IC50 / Ki
S7265	MM-102	MM-102 (HMTase Inhibitor IX) is a high-affinity peptidomimetic inhibitor of the WDR5/MLL1 protein-protein interaction, which bind to WDR5 with Ki < 1 nM and IC50 =2.4nM.	Pan	WDR5, IC50: 2.4 nM
S7833	OICR-9429	OICR-9429 is a potent antagonist of the interaction of WDR5 with peptide regions of MLL and Histone 3 and reduces viability of acute myeloid leukemia cells in vitro. It binds to WDR5 with high affinity (KD = 93 ± 28 nM.	Pan	WDR5, Kd: 93 nM
S2184	WDR5-0103	WDR5-0103 (WD-Repeat Protein 5-0103) is a small-molecule antagonist of WDR5 (WD40 repeat protein 5) with Kd of 450 nM.	Pan	WDR5, Kd: 450 nM; WDR5-MLL interaction, :