| S4701 |
2-DG (2-Deoxy-D-glucose)
|
2-DG (2-Deoxy-D-glucose), 一种葡萄糖类似物，是具有抗病毒活性的糖酵解抑制剂。2-Deoxy-D-glucose 可诱导凋亡并抑制 Herpes Simplex Virus type-1 (HSV-1) receptor 的表达。 |
-
Signal Transduct Target Ther, 2025, 10(1):341
-
Nat Commun, 2025, 16(1):212
-
Cancer Commun (Lond), 2025, 10.1002/cac2.70036
|
|
| S8047 |
Dynasore
|
Dynasore 是一种细胞渗透性的，可逆的，非竞争性dynamin抑制剂，抑制dynamin 1/2的GTPase活性，无细胞试验中IC50为15 μM，也抑制线粒体dynamin Drp1，对其他小GTP酶没有作用效果。Dynasore 可抑制 mTORC1 活性并诱导自噬。Dynasore 抑制多种病毒的入侵，包括HSV。 |
-
J Nanobiotechnology, 2025, 23(1):173
-
Cell Death Dis, 2025, 16(1):681
-
Blood Adv, 2025, bloodadvances.2024015296
|
|
| S7546 |
Pritelivir (BAY 57-1293)
|
Pritelivir (BAY 57-1293, AIC316)是一种强效的helicase primase抑制剂, 其对单纯性疱疹病毒(HSV)HSV-1 和 HSV-2具有抗病毒作用，IC50为20 nM。
|
-
bioRxiv, 2025, 2025.05.12.653380
-
Journal of Virology, 2024, e01836-24
-
PLoS Pathog, 2021, 17(11):e1010117
|
|
| S8428 |
FSL-1
|
FSL-1是一种细菌来源的toll样受体2/6 (toll-like receptor 2/6, TLR2/6)激动剂，可增强对实验性HSV-2感染的抵抗力。 |
|
|
| S9070 |
(2S)-(-)-isoxanthohumol
|
(2S)-(-)-isoxanthohumol is one of the most important prenylflavonoids found in hops. It exhibits an antiproliferative activity against human breast cancer cell lines, ovarian cancer, prostate cancer, and colon cancer cells. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). |
|
|
| S4701 |
2-DG (2-Deoxy-D-glucose)
|
2-DG (2-Deoxy-D-glucose), 一种葡萄糖类似物，是具有抗病毒活性的糖酵解抑制剂。2-Deoxy-D-glucose 可诱导凋亡并抑制 Herpes Simplex Virus type-1 (HSV-1) receptor 的表达。 |
- Signal Transduct Target Ther, 2025, 10(1):341
- Nat Commun, 2025, 16(1):212
- Cancer Commun (Lond), 2025, 10.1002/cac2.70036
|
|
| S8047 |
Dynasore
|
Dynasore 是一种细胞渗透性的，可逆的，非竞争性dynamin抑制剂，抑制dynamin 1/2的GTPase活性，无细胞试验中IC50为15 μM，也抑制线粒体dynamin Drp1，对其他小GTP酶没有作用效果。Dynasore 可抑制 mTORC1 活性并诱导自噬。Dynasore 抑制多种病毒的入侵，包括HSV。 |
- J Nanobiotechnology, 2025, 23(1):173
- Cell Death Dis, 2025, 16(1):681
- Blood Adv, 2025, bloodadvances.2024015296
|
|
| S7546 |
Pritelivir (BAY 57-1293)
|
Pritelivir (BAY 57-1293, AIC316)是一种强效的helicase primase抑制剂, 其对单纯性疱疹病毒(HSV)HSV-1 和 HSV-2具有抗病毒作用，IC50为20 nM。
|
- bioRxiv, 2025, 2025.05.12.653380
- Journal of Virology, 2024, e01836-24
- PLoS Pathog, 2021, 17(11):e1010117
|
|
| S8428 |
FSL-1
|
FSL-1是一种细菌来源的toll样受体2/6 (toll-like receptor 2/6, TLR2/6)激动剂，可增强对实验性HSV-2感染的抵抗力。 |
|
|
| S9070 |
(2S)-(-)-isoxanthohumol
|
(2S)-(-)-isoxanthohumol is one of the most important prenylflavonoids found in hops. It exhibits an antiproliferative activity against human breast cancer cell lines, ovarian cancer, prostate cancer, and colon cancer cells. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). |
|
|
