- S1PR1
- S1PR4
- S1PR5
- S1PR2
S1PR5 激动剂 | 调节剂
| 目录号 | 产品名 | 产品描述 | Selective / Pan | IC50 / Ki |
|---|---|---|---|---|
| S7179 | Siponimod (BAF312) | BAF312 (Siponimod) is a next-generation S1P receptor agonist, selective for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, exhibits >1000-fold selectivity over S1P2, S1P3 and S1P4 receptors. Phase 3. | Pan | S1P5 receptor, EC50: 0.98 nM |
| S7952 | Ozanimod | Ozanimod is a selective oral S1P Receptor 1 modulator. Phase 3. | Pan | S1P5R, EC50: 11 nM |
