Etoposide

别名: VP-16213,VP-16 中文名称:依托泊苷

Etoposide是一种鬼臼毒素的半合成衍生物,通过抑制topoisomerase II 活性而抑制DNA合成,从而增强 DNA 的双链和单链裂解,并可逆地抑制topoisomerase II结合的修复。Etoposide可诱导自噬、线粒体自噬和细胞凋亡。

Etoposide Chemical Structure

Etoposide Chemical Structure

CAS: 33419-42-0

规格 价格 库存 购买数量
10mM (1mL in DMSO) 749.41 现货
100mg 575.72 现货
500mg 2290.17 现货
1g 3439.8 现货
10g 8114.83 现货
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Etoposide相关产品

细胞实验数据示例

细胞系 实验类型 给药浓度 孵育时间 活性描述 文献信息
HT1080 Growth Inhibition Assay 1-100 μM 4/24/48 h induces cell death significantly in a very low concentration 25078064
MCF7 BMI1 Function Assay 10-100 μM 2 h ETOP induces ATM activation 25088203
MCF7 EV Function Assay 10-100 μM 2 h ETOP induces ATM activation 25088203
MCF 7BMI1 Function Assay 10-100 μM 2 h induces production of γH2AX 25088203
MCF7 EV Function Assay 10-100 μM 2 h induces production of γH2AX 25088203
MKL-1  Function Assay 10-1000 nM 4 d induces the induction of MHC-I expression 25116754
NSCs Growth Inhibition Assay 0.01-300 μM 48 h IC50=0.3-3 μM 25119185
UW228-3 Growth Inhibition Assay 0.01-300 μM 48 h IC50=0.99 μM 25119185
DU145 stem-like Function Assay 10-100 μM 2 h increases the pCHK1 expression and decreases the pCHK1 expression in a dose-dependent manner 25149681
DU145 Function Assay 10-100 μM 2 h increases the pCHK1 expression and decreases the pCHK1 expression in a dose-dependent manner 25149681
DU145 stem-like Apoptosis Assay 10-100 μM 8 h induces cell death in a dose-dependent manner 25149681
DU145 Apoptosis Assay 10-100 μM 8 h induces cell death significantly in a very low concentration 25149681
SH-EP  Function Assay 20 μg/ml 24 h increases the expression of endogenous DEPP 25261981
MCF7  Growth Inhibition Assay 5-100 μM 7 d inhibits cell growth in a dose-dependent manner 25472619
SMMC-7721 Function Assay 40 μM 48 h induces γH2AX foci formation 25544361
Hep3B  Function Assay 0.1-10 μM 24 h suppresses the expression of hepcidin mRNA 25633564
Hep3B  Function Assay 10 μM 48 h  reduces the enhancing effect of BMP-6 25633564
HEK293T Growth Inhibition Assay 1-5 μM 48 h  IC50=2.42 ± 0.05 μM 25746763
SW480 Growth Inhibition Assay 0.5-2.5 μM 48 h  IC50=4.92 ± 0.33 μM 25746763
COLO 205 Growth Inhibition Assay 0.5-2.5 μM 48 h  IC50=1.61 ± 0.02 μM 25746763
Caco2 Growth Inhibition Assay 0.5-2.5 μM 48 h  IC50=7.26 ± 1.68 μM 25746763
HT-29 Growth Inhibition Assay 0.5-2.5 μM 48 h  IC50=7.2 ± 1.04 μM 25746763
HCT116 Growth Inhibition Assay 0.5-2.5 μM 48 h  IC50=1.73 ± 0.21 μM 25746763
U87 Growth Inhibition Assay 0-50 μM 48 h decreases cell viability which can be enhanced by silibinin 25750273
HT1080 Function Assay 0.0001-100 μM 1-24 h induces p-p53(ser15) in both time- and concentration-dependent manner 25078064
HT1080 Growth Inhibition Assay 0.0001-100 μM 24 h causes an increase in the number of cells in G2/M, while decreasing S and G1 phase cells 25078064
Kelly Growth Inhibition Assay 0-10 μM 72 h IC50=1.518 μM 25008900
SH-SY5Y  Growth Inhibition Assay 0-10 μM 72 h IC50=0.754 μM  25008900
SK-N-AS Growth Inhibition Assay 0-10 μM 72 h IC50=1.712 μM  25008900
SK-N-DZ Growth Inhibition Assay 0-10 μM 72 h IC50=5.485 μM 25008900
MDA-MB-231 Growth Inhibition Assay 48 h  IC50=12.8 ± 1.0 μM 25216378
T-47D Growth Inhibition Assay 48 h  IC50=7.7 ± 0.7 μM 25216378
MCF-7 Growth Inhibition Assay 48 h  IC50=7.2 ± 0.8 μM 25216378
FaDu Growth Inhibition Assay 72 h IC50=5.02 ± 1.15 μM 25220729
CAL27 Growth Inhibition Assay 72 h IC50=4.27 ± 1.14 μM 25220729
SCC25 Growth Inhibition Assay 72 h IC50=8.41 ± 1.11 μM 25220729
FaDu Growth Inhibition Assay 48 h IC50=6.43 ± 1.13 μM 25220729
CAL27 Growth Inhibition Assay 48 h IC50=18.24 ± 1.15 μM 25220729
SCC25 Growth Inhibition Assay 48 h IC50=20.86 ± 1.07 μM 25220729
FaDu Growth Inhibition Assay 24 h IC50=25.89 ± 1.13 μM 25220729
CAL27 Growth Inhibition Assay 24 h IC50=52.1 ± 1.09 μM 25220729
SCC25 Growth Inhibition Assay 24 h IC50=43.3 ± 1.12 μM 25220729
K/VP.5 Growth Inhibition Assay 72 h IC50=4.9 μM 25282653
K562 Growth Inhibition Assay 72 h IC50=0.29 μM 25282653
HeLa Growth Inhibition Assay 72 h IC50=3.9 ± 2.3 μM 25486219
Jurkat Growth Inhibition Assay 72 h IC50=1.2 ± 1.5 μM 25486219
MCF-7 Growth Inhibition Assay 72 h IC50=10.9 ± 2.1 μM 25486219
MDA-MB-231 Growth Inhibition Assay 72 h IC50=21.2 ± 4.2 μM 25486219
HD-MY-Z Growth Inhibition Assay 24/48/72 h IC50>100 μM 25048236
DOHH-2 Growth Inhibition Assay 24 h IC50>100 μM 25048236
DOHH-2 Growth Inhibition Assay 48 h IC50=19.9 μM 25048236
DOHH-2 Growth Inhibition Assay 72 h IC50=5 μM 25048236
REH Growth Inhibition Assay 24 h IC50=0.027 μM 25048236
REH Growth Inhibition Assay 48 h IC50=0.014 μM 25048236
REH Growth Inhibition Assay 72 h IC50=0.015 μM 25048236
HH Growth Inhibition Assay 24 h IC50=104.7 μM 25048236
HH Growth Inhibition Assay 48 h IC50=48.6 μM 25048236
HH Growth Inhibition Assay 72 h IC50=14.7 μM 25048236
HuT-78 Growth Inhibition Assay 24 h IC50=9.3 μM 25048236
HuT-78 Growth Inhibition Assay 48 h IC50=4.3 μM 25048236
HuT-78 Growth Inhibition Assay 72 h IC50=4.2 μM 25048236
OPM-2 Growth Inhibition Assay 24 h IC50=24.1 μM 25048236
OPM-2 Growth Inhibition Assay 48 h IC50=4 μM 25048236
OPM-2 Growth Inhibition Assay 72 h IC50=1.3 μM 25048236
RPMI-8226 Growth Inhibition Assay 24 h IC50=106.6 μM 25048236
RPMI-8226 Growth Inhibition Assay 48 h IC50=91.1 μM 25048236
RPMI-8226 Growth Inhibition Assay 72 h IC50=14.9 μM 25048236
U-266 Growth Inhibition Assay 24 h IC50=86.2 μM 25048236
U-266 Growth Inhibition Assay 48 h IC50=68.4 μM 25048236
U-266 Growth Inhibition Assay 72 h IC50=27.4 μM 25048236
HepG2 Growth Inhibition Assay 48 h IC50=13.65 ± 0.92 μM 24996136
A549 Growth Inhibition Assay 48 h IC50=241.9 ± 31.23 μM 24996136
MCF7 Growth Inhibition Assay 48 h IC50=81.09 ± 14.21 μM 24996136
HL-60  Growth Inhibition Assay 72 h IC50=0.12 μM 24993014
HL-60[R] Growth Inhibition Assay 72 h IC50=3.12 μM 24993014
MO59K  Growth Inhibition Assay 7 d IC50=0.17 μM 24953561
MO59J Growth Inhibition Assay 7 d IC50=0.1 μM 24953561
ME 180 Growth Inhibition Assay 48 h  IC50=8.9 ± 0.3 μM 24953027
MCF-7 Growth Inhibition Assay 48 h  IC50=23.9 ± 0.3 μM 24953027
HeLa Growth Inhibition Assay 48 h  IC50=4.71 ± 1.4 μM 24953027
MDA-MB-453 Growth Inhibition Assay 48 h  IC50=12.5 ± 0.85 μM 24953027
MDA-MB-231 Growth Inhibition Assay 48 h  IC50=24.22 ± 2.94 μM 24953027
PC-3 Growth Inhibition Assay 48 h  IC50=14.4 ± 3.23 μM 24953027
HT-29 Growth Inhibition Assay 48 h  IC50=21.45 ± 3.87 μM 24953027
BGC-823 Growth Inhibition Assay 48 h  IC50=43.74 ± 5.13 μM 24793877
HeLa Growth Inhibition Assay 48 h  IC50=209.90 ± 13.42  μM 24793877
A549 Growth Inhibition Assay 48 h  IC50=139.54 ± 7.05 μM 24793877
HK-2 Growth Inhibition Assay 48 h  IC50=9.17 ± 1.58 μM 24793877
KB Cytotoxicity assay 3 days Cytotoxicity against human KB cells assessed as reduction in cell number after 3 days, ID50 = 0.2 μM. 1331331
KB Cytotoxicity assay 3 days In vitro cytotoxicity against KB cells after a 3-day incubation., ID50 = 0.2 μM. 2158562
KB Cytotoxicity assay 3 days Cytotoxicity against KB cells after a 3 day incubation, ID50 = 0.2 μM. 8120864
P388 Cytotoxicity assay 1 hr In vitro cytotoxicity against P388 murine leukemia cells in culture in a clonogenic assay after 1 hour exposure to drug, IC50 = 0.3 μM. 8410993
Bel7402 Cytotoxicity assay 5 days Cytotoxicity against human Bel7402 cells after 5 days by MTT assay, IC50 = 1.9 μM. 8778240
BGC Cytotoxicity assay 5 days Cytotoxicity against human BGC cells after 5 days by MTT assay, IC50 = 6.7 μM. 8778240
HCT8 Cytotoxicity assay 5 days Cytotoxicity against human HCT8 cells after 5 days by MTT assay, IC50 = 6.4 μM. 8778240
HL60 Cytotoxicity assay 5 days Cytotoxicity against human HL60 cells after 5 days by MTT assay, IC50 = 0.16 μM. 8778240
C6 Cytotoxicity assay 3 days Cytotoxicity against rat C6 cells after 3 days treated 4 hrs before db-cAMP challenge by MTT assay, LC50 = 0.12 μM. 8988604
HL-60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.025 μM. 11170674
HT-29 Cytotoxicity assay 72 hrs Cytotoxicity against human HT-29 cells after 72 hrs by methylene blue assay, IC50 = 2.3 μM. 14738395
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by methylene blue assay, IC50 = 1.1 μM. 14738395
KB Function assay 3 days Dose required for reduction in camptothecin resistant human nasopharyngeal KB cancer cells after 3 days incubation, ED50 = 7 μM. 15456257
KB-7d Function assay 3 days Dose required for reduction in etoposide resistant human nasopharyngeal KB-7d cancer cells after 3 days incubation, ED50 = 17.2 μM. 15456257
A549 Function assay 3 days Dose required for reduction in human lung A549 cancer cells after 3 days incubation, ED50 = 10.6 μM. 15456257
KB Function assay 3 days Dose required to cause reduction in human nasopharyngeal KB cancer cells after 3 days incubation, ED50 = 0.3 μM. 15456257
1A9 Function assay 3 days Dose required to cause reduction in human ovarian 1A9 cancer cells after 3 days incubation, ED50 = 0.15 μM. 15456257
HSC2 Cytotoxicity assay 24 hrs Cytotoxicity against human HSC2 cells assessed as cell viability after 24 hrs, IC50 = 41 μM. 15620262
HL60 Cytotoxicity assay 24 hrs Cytotoxicity against human HL60 cells after 24 hrs by MTT assay, IC50 = 25 μM. 15974617
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay, IC50 = 0.8775 μM. 16309315
TK10 Cytotoxicity assay 48 hrs Cytotoxicity against human TK10 cells after 48 hrs by SRB assay, IC50 = 9.9525 μM. 16309315
UACC62 Cytotoxicity assay 48 hrs Cytotoxicity against human UACC62 cells after 48 hrs by SRB assay, IC50 = 1.13 μM. 16309315
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, ED50 = 3.76 μM. 16441087
HeLa Antiproliferative assay 69 hrs Antiproliferative effect against human HeLa cells after 69 hrs by MTT assay, IC50 = 3.6 μM. 16499324
HL60 Antiproliferative assay 69 hrs Antiproliferative effect against human HL60 cells after 69 hrs, IC50 = 0.21 μM. 16499324
MCF7 Antiproliferative assay 72 hrs Antiproliferative effect against human MCF7 cells after 72 hrs by MTT assay, IC50 = 0.19 μM. 16499324
K-562 Cytotoxicity assay 72 hrs Cytotoxicity against human K-562 cells after 72 hrs by MTT assay, IC50 = 1.87 μM. 16872135
LAMA-84 Cytotoxicity assay 72 hrs Cytotoxicity against human LAMA-84 cells after 72 hrs by MTT assay, IC50 = 0.79 μM. 16872135
SKW3 Cytotoxicity assay 72 hrs Cytotoxicity against human SKW3 cells after 72 hrs by MTT assay, IC50 = 0.82 μM. 16872135
HL-60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL-60 cells after 72 hrs by MTT assay, IC50 = 10.5 μM. 16933865
HSC2 Cytotoxicity assay 24 hrs Cytotoxicity against human HSC2 cells after 24 hrs by MTT assay, IC50 = 24 μM. 17125230
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs, IC50 = 2 μM. 17125231
MCF7 Cytotoxicity assay 48 hrs Cytotoxic activity against human MCF7 cells after 48 hrs by MTT reduction assay, IC50 = 3.2 μM. 17316916
K562 Growth inhibition assay 5 days Growth inhibition of K562 cells by XTT assay after 5 days, IC50 = 0.32 μM. 17411092
BV173 Cytotoxicity assay 72 hrs Cytotoxicity against human BV173 cells after 72 hrs by MTT assay, IC50 = 0.9 μM. 17459529
K562 Cytotoxicity assay 72 hrs Cytotoxicity against human K562 cells after 72 hrs by MTT assay, IC50 = 3.1 μM. 17459529
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by SRB method, IC50 = 0.32 μM. 17493824
HCT15 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT15 cells after 48 hrs by SRB method, IC50 = 2.43 μM. 17493824
SK-MEL-2 Cytotoxicity assay 48 hrs Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB method, IC50 = 0.3 μM. 17493824
SKOV3 Cytotoxicity assay 48 hrs Cytotoxicity against human SKOV3 cells after 48 hrs by SRB method, IC50 = 1.72 μM. 17493824
HL20 Growth inhibition assay 48 hrs Inhibition of cell growth in human HL20 cells after 48 hrs by MTT assay, IC50 = 0.315 μM. 17889547
HeLa Growth inhibition assay 48 hrs Growth inhibition of HeLa cells after 48 hrs by MTT assay, GI50 = 8 μM. 17894480
HeLa Antitumor assay 72 hrs Antitumor activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 3 μM. 17935309
MiaPaCa2 Antitumor assay 72 hrs Antitumor activity against human MiaPaCa2 cells after 72 hrs by MTT assay, IC50 = 15 μM. 17935309
SW620 Antitumor assay 72 hrs Antitumor activity against human SW620 cells after 72 hrs by MTT assay, IC50 = 20 μM. 17935309
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, GI50 = 0.14 μM. 17962028
K562 Cytotoxicity assay 5 days Cytotoxicity against human K562 cells after 5 days by XTT assay, IC50 = 0.32 μM. 18076140
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 2.9 μM. 18258438
AGS Antitumor assay 72 hrs Antitumor against human AGS cells after 72 hrs by MTT assay, IC50 = 0.36 μM. 18299197
HL60 Antitumor assay 72 hrs Antitumor against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.8 μM. 18299197
J82 Antitumor assay 72 hrs Antitumor against human J82 cells after 72 hrs by MTT assay, IC50 = 2.8 μM. 18299197
SK-MES1 Antitumor assay 72 hrs Antitumor against human SK-MES1 cells after 72 hrs by MTT assay, IC50 = 2.5 μM. 18299197
MRC5 Cytotoxicity assay 72 hrs Cytotoxicity against human MRC5 cells after 72 hrs by MTT assay, IC50 = 3.9 μM. 18299197
H520 Cytotoxicity assay 72 hrs Cytotoxicity against human H520 cells after 72 hrs by Cell Titer 96 Aqueous Non-Radioactive assay, GI50 = 8.7 μM. 18321710
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells after 72 hrs by Cell Titer 96 Aqueous Non-Radioactive assay, GI50 = 11.1 μM. 18321710
A549 Cytotoxicity assay 3 days Cytotoxicity against human A549 cells after 3 days by SRB assay, IC50 = 1.16 μM. 18321715
HCT15 Cytotoxicity assay 3 days Cytotoxicity against human HCT15 cells after 3 days by SRB assay, IC50 = 2.8 μM. 18321715
HL60 Cytotoxicity assay 3 days Cytotoxicity against human HL60 cells after 3 days by SRB assay, IC50 = 0.37 μM. 18321715
HT1080 Cytotoxicity assay 3 days Cytotoxicity against human HT1080 cells after 3 days by SRB assay, IC50 = 0.25 μM. 18321715
SK-MEL-2 Cytotoxicity assay 3 days Cytotoxicity against human SK-MEL-2 cells after 3 days by SRB assay, IC50 = 5.72 μM. 18321715
SKOV3 Cytotoxicity assay 3 days Cytotoxicity against human SKOV3 cells after 3 days by SRB assay, IC50 = 4.28 μM. 18321715
SNU638 Cytotoxicity assay 3 days Cytotoxicity against human SNU638 cells after 3 days by SRB assay, IC50 = 0.23 μM. 18321715
XF498 Cytotoxicity assay 3 days Cytotoxicity against human XF498 cells after 3 days by SRB assay, IC50 = 3.48 μM. 18321715
HL60 Apoptosis assay 48 hrs Induction of apoptosis in human HL60 cells after 48 hrs, AC50 = 0.4 μM. 18339455
5637 Antiproliferative assay 96 hrs Antiproliferative activity against human 5637 cells after 96 hrs by crystal violet assay, IC50 = 0.54 μM. 18434163
A427 Antiproliferative assay 96 hrs Antiproliferative activity against human A427 cells after 96 hrs by crystal violet assay, IC50 = 0.13 μM. 18434163
KYSE70 Antiproliferative assay 96 hrs Antiproliferative activity against human KYSE70 cells after 96 hrs by crystal violet assay, IC50 = 0.94 μM. 18434163
MCF7 Antiproliferative assay 96 hrs Antiproliferative activity against human MCF7 cells after 96 hrs by crystal violet assay, IC50 = 0.5 μM. 18434163
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human mitoxantrone-sensitive HL60 cells after 72 hrs, IC50 = 0.486 μM. 18507368
HL60/MX2 Cytotoxicity assay 72 hrs Cytotoxicity against mitoxantrone-resistant human HL60/MX2 cells after 72 hrs, IC50 = 48.5 μM. 18507368
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.2 μM. 18507472
HL60 Antiproliferative assay 48 hrs Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay, IC50 = 0.315 μM. 18513974
K562 Antiproliferative assay 48 hrs Antiproliferative activity against human K562 cells after 48 hrs by MTT assay, IC50 = 1.27 μM. 18514972
KB Antiproliferative assay 48 hrs Antiproliferative activity against human KB cells after 48 hrs by MTT assay, IC50 = 0.42 μM. 18514972
L02 Antiproliferative assay 48 hrs Antiproliferative activity against human L02 cells after 48 hrs by MTT assay, IC50 = 13 μM. 18514972
DU145 ATCC HTB 81 Cytotoxicity assay 72 hrs Cytotoxicity against human DU145 ATCC HTB 81 cells after 72 hrs by MTT assay, IC50 = 1.5 μM. 18558490
K562 ATCC CCL 243 Cytotoxicity assay 72 hrs Cytotoxicity against human K562 ATCC CCL 243 cells after 72 hrs by MTT assay, IC50 = 4.9 μM. 18558490
MCF7 ATCC HTB 22 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 ATCC HTB 22 cells after 72 hrs by MTT assay, IC50 = 12.2 μM. 18558490
U251 RCB 0641 Cytotoxicity assay 72 hrs Cytotoxicity against human U251 RCB 0641 cells after 72 hrs by MTT assay, IC50 = 0.5 μM. 18558490
3LL CRL 1642 Cytotoxicity assay 48 hrs Cytotoxicity against mouse 3LL CRL 1642 cells after 48 hrs by MTT assay, IC50 = 4 μM. 18558490
L1210 ATCC CCL 219 Cytotoxicity assay 48 hrs Cytotoxicity against mouse L1210 ATCC CCL 219 cells after 48 hrs by MTT assay, IC50 = 0.5 μM. 18558490
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 8.37 μM. 18844422
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by MTT assay, IC50 = 1.25 μM. 18844422
AGS Cytotoxicity assay 3 days Cytotoxicity against human AGS cells after 3 days by MTT assay, IC50 = 0.36 μM. 19013074
HL-60 Cytotoxicity assay 3 days Cytotoxicity against human HL-60 cells after 3 days by MTT assay, IC50 = 0.8 μM. 19013074
J82 Cytotoxicity assay 3 days Cytotoxicity against human J82 cells after 3 days by MTT assay, IC50 = 2.8 μM. 19013074
MRC5 Cytotoxicity assay 3 days Cytotoxicity against human MRC5 cells after 3 days by MTT assay, IC50 = 3.9 μM. 19013074
SK-MES-1 Cytotoxicity assay 3 days Cytotoxicity against human SK-MES-1 cells after 3 days by MTT assay, IC50 = 2.5 μM. 19013074
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 5.9 μM. 19053514
HL-60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL-60 cells after 72 hrs by MTT assay, IC50 = 0.25 μM. 19053514
U937 Cytotoxicity assay 72 hrs Cytotoxicity against human U937 cells after 72 hrs by MTT assay, IC50 = 0.92 μM. 19053514
ACHN Antiproliferative assay 96 hrs Antiproliferative activity against human ACHN cells after 96 hrs by MTT assay, IC50 = 2.15 μM. 19053767
CCRF-CEM Antiproliferative assay 96 hrs Antiproliferative activity against human CCRF-CEM cells after 96 hrs by MTT assay, IC50 = 1.2 μM. 19053767
CCRF-SB Antiproliferative assay 96 hrs Antiproliferative activity against human CCRF-SB cells after 96 hrs by MTT assay, IC50 = 0.1 μM. 19053767
HeLa Antiproliferative assay 96 hrs Antiproliferative activity against human HeLa cells after 96 hrs by MTT assay, IC50 = 3 μM. 19053767
HT-29 Antiproliferative assay 96 hrs Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay, IC50 = 2.5 μM. 19053767
MCF7 Antiproliferative assay 96 hrs Antiproliferative activity against human MCF7 cells after 96 hrs by MTT assay, IC50 = 1 μM. 19053767
MRC5 Antiproliferative assay 96 hrs Antiproliferative activity against human MRC5 cells after 96 hrs by MTT assay, IC50 = 3.9 μM. 19053767
MT4 Antiproliferative assay 96 hrs Antiproliferative activity against human MT4 cells after 96 hrs by MTT assay, IC50 = 1.25 μM. 19053767
SF-268 Antiproliferative assay 96 hrs Antiproliferative activity against human SF-268 cells after 96 hrs by MTT assay, IC50 = 3.25 μM. 19053767
XF498 Antiproliferative assay 96 hrs Antiproliferative activity against human XF498 cells after 96 hrs by MTT assay, IC50 = 3.45 μM. 19053767
KB Growth inhibition assay 72 hrs Growth inhibition of human KB cells after 72 hrs by methylene blue dye assay, IC50 = 1.1 μM. 19053773
KB-TAX50 Growth inhibition assay 72 hrs Growth inhibition of human Pgp170 overexpressing multidrug resistant-KB-TAX50 cells after 72 hrs by methylene blue dye assay, IC50 = 3.5 μM. 19053773
KB-VIN10 Growth inhibition assay 72 hrs Growth inhibition of human Pgp170 overexpressing multidrug resistant-KB-VIN10 cells after 72 hrs by methylene blue dye assay, IC50 = 23 μM. 19053773
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by WST-8 assay, IC50 = 1.7 μM. 19072209
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by WST-8 assay, IC50 = 7.6 μM. 19072209
NB4 Cytotoxicity assay 48 hrs Cytotoxicity against human NB4 cells after 48 hrs by WST-8 assay, IC50 = 1.3 μM. 19072209
PC3 Cytotoxicity assay 48 hrs Cytotoxicity against human PC3 cells after 48 hrs by WST-8 assay, IC50 = 13.6 μM. 19072209
SH-SY5Y Cytotoxicity assay 48 hrs Cytotoxicity against human SH-SY5Y cells after 48 hrs by WST-8 assay, IC50 = 1.7 μM. 19072209
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs, IC50 = 1.2 μM. 19115839
DLD1 Cytotoxicity assay 48 hrs Cytotoxicity against human DLD1 cells after 48 hrs, IC50 = 27 μM. 19115839
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs, IC50 = 0.7 μM. 19115839
PC3 Cytotoxicity assay 48 hrs Cytotoxicity against human PC3 cells after 48 hrs, IC50 = 1.7 μM. 19115839
WS1 Cytotoxicity assay 48 hrs Cytotoxicity against human WS1 cells after 48 hrs, IC50 = 34 μM. 19115839
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 3.3 μM. 19251420
AGS Cytotoxicity assay 72 hrs Cytotoxicity against human AGS cells after 72 hrs by MTT assay, IC50 = 0.36 μM. 19269832
J82 Cytotoxicity assay 72 hrs Cytotoxicity against human J82 cells after 72 hrs by MTT assay, IC50 = 2.8 μM. 19269832
MRC5 Cytotoxicity assay 72 hrs Cytotoxicity against human MRC5 cells after 72 hrs by MTT assay, IC50 = 3.9 μM. 19269832
SKMES1 Cytotoxicity assay 72 hrs Cytotoxicity against human SKMES1 cells after 72 hrs by MTT assay, IC50 = 2.5 μM. 19269832
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 14.3 μM. 19394829
CCRF-CEM Cytotoxicity assay 72 hrs Cytotoxicity against human CCRF-CEM cells after 72 hrs by MTT assay, IC50 = 1.1 μM. 19394829
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 3.9 μM. 19394829
Jurkat Cytotoxicity assay 72 hrs Cytotoxicity against human Jurkat cells after 72 hrs by MTT assay, IC50 = 1.2 μM. 19394829
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 10.9 μM. 19394829
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay, IC50 = 21.2 μM. 19394829
AGS Cytotoxicity assay 3 days Cytotoxicity against human AGS cells after 3 days by MTT assay, IC50 = 0.36 μM. 19419803
HL60 Cytotoxicity assay 3 days Cytotoxicity against human HL60 cells after 3 days by MTT assay, IC50 = 0.8 μM. 19419803
J82 Cytotoxicity assay 3 days Cytotoxicity against human J82 cells after 3 days by MTT assay, IC50 = 2.5 μM. 19419803
MRC5 Cytotoxicity assay 3 days Cytotoxicity against human MRC5 cells after 3 days by MTT assay, IC50 = 3.93 μM. 19419803
SKMES1 Cytotoxicity assay 3 days Cytotoxicity against human SKMES1 cells after 3 days by MTT assay, IC50 = 2.8 μM. 19419803
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by SRB method, IC50 = 1.7 μM. 19425589
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by SRB method, IC50 = 7.6 μM. 19425589
NB4 Cytotoxicity assay 48 hrs Cytotoxicity against human NB4 cells after 48 hrs by SRB method, IC50 = 1.3 μM. 19425589
PC3 Cytotoxicity assay 48 hrs Cytotoxicity against human PC3 cells after 48 hrs by SRB method, IC50 = 13.6 μM. 19425589
SH-SY5Y Cytotoxicity assay 48 hrs Cytotoxicity against human SH-SY5Y cells after 48 hrs by SRB method, IC50 = 1.7 μM. 19425589
HT-29 Cytotoxicity assay 96 hrs Cytotoxicity against human HT-29 cells after 96 hrs by SRB assay, GI50 = 0.73 μM. 19572549
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 0.63 μM. 19685913
Bel7402 Cytotoxicity assay 72 hrs Cytotoxicity against human Bel7402 cells after 72 hrs by MTT assay, IC50 = 1.03 μM. 19685913
HL60 Cytotoxicity assay 24 hrs Cytotoxicity against human HL60 cells after 24 hrs by SRB assay, IC50 = 0.042 μM. 19685913
P388 Cytotoxicity assay 24 hrs Cytotoxicity against mouse P388 cells after 24 hrs by SRB assay, IC50 = 0.05 μM. 19685913
HCT116 Antiproliferative assay 3 days Antiproliferative activity against human HCT116 cells after 3 days by XTT assay, IC50 = 1.7 μM. 19691293
SW948 Antiproliferative assay 3 days Antiproliferative activity against human SW948 cells after 3 days by XTT assay, IC50 = 1.3 μM. 19691293
A549 Cytotoxicity assay 24 hrs Cytotoxicity against human A549 cells after 24 hrs by SRB assay, IC50 = 0.63 μM. 19769341
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.042 μM. 19769341
HONE1 Cytotoxicity assay 72 hrs Cytotoxicity against human HONE1 cells after 72 hrs by methylene blue dye assay, IC50 = 1.2 μM. 19785430
HT-29 Cytotoxicity assay 72 hrs Cytotoxicity against human HT-29 cells after 72 hrs by methylene blue dye assay, IC50 = 2.3 μM. 19785430
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by methylene blue dye assay, IC50 = 1.3 μM. 19785430
HCT116 Cytotoxicity assay 4 days Cytotoxicity against human HCT116 cells after 4 days, IC50 = 14.39 μM. 19800803
HaCaT Cytotoxicity assay 72 hrs Cytotoxicity against human HaCaT cells after 72 hrs by MTT assay, IC50 = 0.55 μM. 19919064
B16 Cytotoxicity assay 72 hrs Cytotoxicity against mouse B16 cells after 72 hrs by MTT assay, IC50 = 0.28 μM. 19919064
DU145 Cytotoxicity assay 4 days Cytotoxicity against human DU145 cells after 4 days by ELISA reader assay, IC50 = 1.3 μM. 19939682
HCT15 Cytotoxicity assay 4 days Cytotoxicity against human HCT15 cells after 4 days by ELISA reader assay, IC50 = 1.09 μM. 19939682
HeLa Cytotoxicity assay 4 days Cytotoxicity against human HeLa cells after 4 days by ELISA reader assay, IC50 = 1.29 μM. 19939682
K562 Cytotoxicity assay 4 days Cytotoxicity against human K562 cells after 4 days by ELISA reader assay, IC50 = 2.41 μM. 19939682
MCF7 Cytotoxicity assay 4 days Cytotoxicity against human MCF7 cells after 4 days by ELISA reader assay, IC50 = 1.89 μM. 19939682
DU145 Cytotoxicity assay 3 days Cytotoxicity against human DU145 cells after 3 days, IC50 = 21.07 μM. 19954977
HCT116 Cytotoxicity assay 3 days Cytotoxicity against human HCT116 cells after 3 days, IC50 = 17.92 μM. 19954977
HeLa Cytotoxicity assay 3 days Cytotoxicity against human HeLa cells after 3 days, IC50 = 8.43 μM. 19954977
MCF7 Cytotoxicity assay 3 days Cytotoxicity against human MCF7 cells after 3 days, IC50 = 18.01 μM. 19954977
MDA-MB-231 Cytotoxicity assay 3 days Cytotoxicity against human MDA-MB-231 cells after 3 days, IC50 = 16.85 μM. 19954977
K562 Cytotoxicity assay 72 hrs Cytotoxicity against human K562 cells after 72 hrs by MTS assay, IC50 = 0.42 μM. 20006518
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs, IC50 = 0.29 μM. 20053564
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells after 48 hrs, IC50 = 0.42 μM. 20053564
RPMI8226 Cytotoxicity assay 48 hrs Cytotoxicity against human RPMI8226 cells after 48 hrs, IC50 = 0.14 μM. 20053564
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 0.83 μM. 20071056
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells after 72 hrs by CCK8 method, IC50 = 0.18 μM. 20071056
RPMI8226 Cytotoxicity assay 72 hrs Cytotoxicity against human RPMI8226 cells after 72 hrs by CCK8 method, IC50 = 0.7 μM. 20071056
DU145 Cytotoxicity assay 48 hrs Cytotoxicity against human DU145 cells after 48 hrs by MTT assay, IC50 = 1.63 μM. 20093033
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 0.47 μM. 20093033
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 0.97 μM. 20093033
HT-29 Cytotoxicity assay 48 hrs Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 1.42 μM. 20093033
MDA-MB-231 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 2.87 μM. 20093033
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by MTT assay, ED50 = 0.2 μM. 20187635
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by MTT assay, IC50 = 0.6 μM. 20187635
KB1 Cytotoxicity assay 72 hrs Cytotoxicity against human KB1 cells after 72 hrs by MTT assay, IC50 = 34.8 μM. 20187635
KB-7d Cytotoxicity assay 72 hrs Cytotoxicity against human KB-7d cells after 72 hrs by MTT assay, ED50 = 25 μM. 20187635
KB Cytotoxicity assay 72 hrs Cytotoxicity against human vincristine-resistant KB cells after 72 hrs by MTT assay, IC50 = 28.7 μM. 20187635
NCI-H460 Cytotoxicity assay 48 hrs Cytotoxicity against human NCI-H460 cells after 48 hrs by [3H]thymidine incorporation assay, IC50 = 0.09 μM. 20210346
SKHEP1 Cytotoxicity assay 48 hrs Cytotoxicity against human SKHEP1 cells after 48 hrs by [3H]thymidine incorporation assay, IC50 = 0.062 μM. 20210346
U87MG Cytotoxicity assay 48 hrs Cytotoxicity against human U87MG cells after 48 hrs by [3H]thymidine incorporation assay, IC50 = 0.145 μM. 20210346
HepG2 Growth inhibition assay 72 hrs Growth inhibition of human HepG2 cells after 72 hrs by sulforhodamine B assay, IC50 = 4.1 μM. 20346660
DU145 Cytotoxicity assay 2 days Cytotoxicity against human DU145 cells after 2 days by automatic ELISA reader system, IC50 = 0.5 μM. 20392646
HCT15 Cytotoxicity assay 2 days Cytotoxicity against human HCT15 cells after 2 days by automatic ELISA reader system, IC50 = 1.1 μM. 20392646
HeLa Cytotoxicity assay 2 days Cytotoxicity against human HeLa cells after 2 days by automatic ELISA reader system, IC50 = 1.4 μM. 20392646
HL60 Cytotoxicity assay 2 days Cytotoxicity against human HL60 cells after 2 days by automatic ELISA reader system, IC50 = 1 μM. 20392646
MDA-MB-231 Cytotoxicity assay 2 days Cytotoxicity against human MDA-MB-231 cells after 2 days by automatic ELISA reader system, IC50 = 0.7 μM. 20392646
HM-SFME-1 Antiproliferative assay 24 hrs Antiproliferative activity against mouse r/m HM-SFME-1 cells after 24 hrs by MTT assay, IC50 = 9 μM. 20398972
SFME Antiproliferative assay 24 hrs Antiproliferative activity against mouse SFME cells after 24 hrs by MTT assay, IC50 = 0.5 μM. 20398972
HT-29 Cytotoxicity assay 48 hrs Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 30.38 μM. 20405844
MDA-MB-231 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 23.22 μM. 20405844
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by resazurin reduction assay, IC50 = 16 μM. 20413315
DLD1 Cytotoxicity assay 48 hrs Cytotoxicity against human DLD1 cells after 48 hrs by resazurin reduction assay, IC50 = 10 μM. 20413315
WS1 Cytotoxicity assay 48 hrs Cytotoxicity against human WS1 cells after 48 hrs by resazurin reduction assay, IC50 = 4.3 μM. 20413315
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by SRB assay, IC50 = 0.63 μM. 20415462
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.042 μM. 20415462
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.39 μM. 20524638
HL60/MX2 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60/MX2 cells after 72 hrs by MTT assay, IC50 = 11.9 μM. 20570510
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human topoisomerase 2-sensitive HL60 cells after 72 hrs by MTT assay, IC50 = 1.3 μM. 20570510
A375 Cytotoxicity assay 24 hrs Cytotoxicity activity against human A375 cells after 24 hrs by NRU assay, IC50 = 19 μM. 20570625
A375 Cytotoxicity assay 48 hrs Cytotoxicity activity against human A375 cells after 48 hrs by NRU assay, IC50 = 12 μM. 20570625
B16 Cytotoxicity assay 24 hrs Cytotoxicity activity against mouse B16 cells after 24 hrs by NRU assay, IC50 = 9 μM. 20570625
B16 Cytotoxicity assay 48 hrs Cytotoxicity activity against mouse B16 cells after 48 hrs by NRU assay, IC50 = 0.13 μM. 20570625
DU145 Cytotoxicity assay 4 days Cytotoxicity against human DU145 cells after 4 days by MTT assay, IC50 = 13.8 μM. 20619511
HCT116 Cytotoxicity assay 4 days Cytotoxicity against human HCT116 cells after 4 days by MTT assay, IC50 = 11.9 μM. 20619511
HeLa Cytotoxicity assay 4 days Cytotoxicity against human HeLa cells after 4 days by MTT assay, IC50 = 18.2 μM. 20619511
MCF7 Cytotoxicity assay 4 days Cytotoxicity against human MCF7 cells after 4 days by MTT assay, IC50 = 17.5 μM. 20619511
MDA-MB-231 Cytotoxicity assay 4 days Cytotoxicity against human MDA-MB-231 cells after 4 days by MTT assay, IC50 = 16.3 μM. 20619511
AGS Cytotoxicity assay 72 hrs Cytotoxicity against human AGS cells after 72 hrs by MTT assay, IC50 = 0.36 μM. 20828890
HL-60(TB) Cytotoxicity assay 72 hrs Cytotoxicity against human HL-60(TB) cells after 72 hrs by MTT assay, IC50 = 0.8 μM. 20828890
J82 Cytotoxicity assay 72 hrs Cytotoxicity against human J82 cells after 72 hrs by MTT assay, IC50 = 2.8 μM. 20828890
MRC5 Cytotoxicity assay 72 hrs Cytotoxicity against human MRC5 cells after 72 hrs by MTT assay, IC50 = 3.9 μM. 20828890
SKMES1 Cytotoxicity assay 72 hrs Cytotoxicity against human SKMES1 cells after 72 hrs by MTT assay, IC50 = 2.5 μM. 20828890
colon cancer cells Growth inhibition assay 72 hrs Growth inhibition of human colon cancer cells after 72 hrs by sulforhodamine B assay, GI50 = 1.3 μM. 20884089
gastric cancer cells Growth inhibition assay 72 hrs Growth inhibition of human gastric cancer cells after 72 hrs by sulforhodamine B assay, GI50 = 1.3 μM. 20884089
lung cancer cells Growth inhibition assay 72 hrs Growth inhibition of human lung cancer cells after 72 hrs by sulforhodamine B assay, GI50 = 1.3 μM. 20884089
HCT15 Antiproliferative assay 48 hrs Antiproliferative activity against human HCT15 cells after 48 hrs by sulforhodamine B assay, IC50 = 1.6 μM. 20939516
MESSA Antiproliferative assay 48 hrs Antiproliferative activity against human MESSA cells after 48 hrs by sulforhodamine B assay, IC50 = 0.3 μM. 20939516
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells after 72 hrs, IC50 = 0.486 μM. 20961767
HL60/MX2 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60/MX2 cells after 72 hrs, IC50 = 48.5 μM. 20961767
KB Cytotoxicity assay 3 days Cytotoxicity against human KB cells after 3 days by sulforhodamine B assay, EC50 = 4.5 μM. 21028898
502713 Anticancer assay 48 hrs Anticancer activity against human 502713 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 0.1 μM. 21074444
A549 Anticancer assay 48 hrs Anticancer activity against human A549 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 3.08 μM. 21074444
DU145 Anticancer assay 48 hrs Anticancer activity against human DU145 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 3.7 μM. 21074444
HCT15 Anticancer assay 48 hrs Anticancer activity against human HCT15 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 0.9 μM. 21074444
Hep2 Anticancer assay 48 hrs Anticancer activity against human Hep2 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 0.9 μM. 21074444
IMR32 Anticancer assay 48 hrs Anticancer activity against human IMR32 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 6.3 μM. 21074444
PC3 Anticancer assay 48 hrs Anticancer activity against human PC3 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 2.6 μM. 21074444
HT-29 Cytotoxicity assay 72 hrs Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay, GI50 = 31.62 μM. 21115210
K562 Cytotoxicity assay 72 hrs Cytotoxicity against human K562 cells after 72 hrs by MTT assay, GI50 = 12.59 μM. 21115210
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, GI50 = 19.95 μM. 21115210
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells after 72 hrs by MTT assay, GI50 = 0.63 μM. 21115210
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells after 72 hrs by MTT assay, TGI = 3.98 μM. 21115210
95-D Cytotoxicity assay 72 hrs Cytotoxicity against human 95-D cells after 72 hrs by MTT assay, IC50 = 0.0202 μM. 21145139
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 0.00256 μM. 21145139
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by MTT assay, IC50 = 0.00461 μM. 21145139
KB/VCR Cytotoxicity assay 72 hrs Cytotoxicity against human KB/VCR cells after 72 hrs by MTT assay, IC50 = 0.0834 μM. 21145139
A549 Cytotoxicity assay 3 days Cytotoxicity against human A549 cells assessed as cell growth inhibition after 3 days by MTT assay, IC50 = 21.4 μM. 21277655
HCT116 Cytotoxicity assay 3 days Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 3 days by MTT assay, IC50 = 13.5 μM. 21277655
HepG2 Cytotoxicity assay 3 days Cytotoxicity against human HepG2 cells assessed as cell growth inhibition after 3 days by MTT assay, IC50 = 4.9 μM. 21277655
HT1080 Antiproliferative assay 96 hrs Antiproliferative activity against human HT1080 cells after 96 hrs by MTT assay, IC50 = 0.75 μM. 21296467
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 11 μM. 21397370
A2780 Cytotoxicity assay 48 hrs Cytotoxicity against human A2780 cells after 48 hrs by sulforhodamine B based ELISA, GI50 = 1.3 μM. 21402478
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B based ELISA, GI50 = 3.08 μM. 21402478
COLO205 Cytotoxicity assay 48 hrs Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B based ELISA, GI50 = 0.13 μM. 21402478
KB Cytotoxicity assay 48 hrs Cytotoxicity against human KB cells after 48 hrs by sulforhodamine B based ELISA, GI50 = 0.3 μM. 21402478
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by sulforhodamine B based ELISA, GI50 = 2.1 μM. 21402478
DU145 Cytotoxicity assay 2 days Cytotoxicity against human DU145 cells after 2 days, IC50 = 2.19 μM. 21419530
HCT116 Cytotoxicity assay 2 days Cytotoxicity against human HCT116 cells after 2 days, IC50 = 9.5 μM. 21419530
HeLa Cytotoxicity assay 2 days Cytotoxicity against human HeLa cells after 2 days, IC50 = 2.36 μM. 21419530
HL60 Cytotoxicity assay 2 days Cytotoxicity against human HL60 cells after 2 days, IC50 = 1.28 μM. 21419530
MDA-MB-231 Cytotoxicity assay 2 days Cytotoxicity against human MDA-MB-231 cells after 2 days, IC50 = 1.23 μM. 21419530
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay, IC50 = 5.62 μM. 21477899
HCT15 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay, IC50 = 7.15 μM. 21477899
Hep2 Cytotoxicity assay 48 hrs Cytotoxicity against human Hep2 cells after 48 hrs by sulforhodamine B assay, IC50 = 2.15 μM. 21477899
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by sulforhodamine B assay, IC50 = 19 μM. 21477899
PC3 Cytotoxicity assay 48 hrs Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay, IC50 = 17.5 μM. 21477899
SF295 Cytotoxicity assay 48 hrs Cytotoxicity against human SF295 cells after 48 hrs by sulforhodamine B assay, IC50 = 13.5 μM. 21477899
A2780 Growth inhibition assay 48 hrs Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.3 μM. 21489802
A549 Growth inhibition assay 48 hrs Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.08 μM. 21489802
COLO205 Growth inhibition assay 48 hrs Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.13 μM. 21489802
DWD Growth inhibition assay 48 hrs Growth inhibition of human DWD cells after 48 hrs by sulforhodamine B assay, GI50 = 0.6 μM. 21489802
Gurav Growth inhibition assay 48 hrs Growth inhibition of human Gurav cells after 48 hrs by sulforhodamine B assay, GI50 = 0.5 μM. 21489802
HOP62 Growth inhibition assay 48 hrs Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.8 μM. 21489802
KB Growth inhibition assay 48 hrs Growth inhibition of human KB cells after 48 hrs by sulforhodamine B assay, GI50 = 0.3 μM. 21489802
MCF7 Growth inhibition assay 48 hrs Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.1 μM. 21489802
PC3 Growth inhibition assay 48 hrs Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.6 μM. 21489802
SiHa Growth inhibition assay 48 hrs Growth inhibition of human SiHa cells after 48 hrs by sulforhodamine B assay, GI50 = 3.1 μM. 21489802
ZR-75-1 Growth inhibition assay 48 hrs Growth inhibition of human ZR-75-1 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.2 μM. 21489802
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 4 μM. 21570846
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by MTT assay, IC50 = 10 μM. 21570846
DU145 Cytotoxicity assay 2 days Cytotoxicity against human DU145 cells after 2 days, IC50 = 0.5 μM. 21601964
HCT15 Cytotoxicity assay 2 days Cytotoxicity against human HCT15 cells after 2 days, IC50 = 1.1 μM. 21601964
HeLa Cytotoxicity assay 2 days Cytotoxicity against human HeLa cells after 2 days, IC50 = 1.4 μM. 21601964
HL60 Cytotoxicity assay 2 days Cytotoxicity against human HL60 cells after 2 days, IC50 = 1 μM. 21601964
MDA-MB-231 Cytotoxicity assay 2 days Cytotoxicity against human MDA-MB-231 cells after 2 days, INH = 0.7 μM. 21601964
AGS Anticancer assay 3 days Anticancer activity against human AGS cells after 3 days by MTT assay, IC50 = 0.36 μM. 21621882
J82 Anticancer assay 3 days Anticancer activity against human J82 cells after 3 days by MTT assay, IC50 = 0.8 μM. 21621882
MRC5 Anticancer assay 3 days Anticancer activity against human MRC5 cells after 3 days by MTT assay, IC50 = 3.9 μM. 21621882
SKMES1 Anticancer assay 3 days Anticancer activity against human SKMES1 cells after 3 days by MTT assay, IC50 = 2.8 μM. 21621882
Caco2 Cytotoxicity assay 72 hrs Cytotoxicity against human Caco2 cells after 72 hrs by MTS assay, IC50 = 18.6 μM. 21724394
CCD-18Co Cytotoxicity assay 72 hrs Cytotoxicity against human CCD-18Co cells after 72 hrs by MTS assay, IC50 = 44.4 μM. 21724394
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay, IC50 = 25.5 μM. 21724394
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 14.8 μM. 21733601
SiHa Cytotoxicity assay 48 hrs Cytotoxicity against human SiHa cells after 48 hrs by MTT assay, IC50 = 30.7 μM. 21733601
A2780 Cytotoxicity assay 48 hrs Cytotoxicity against human A2780 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.3 μM. 21737288
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.08 μM. 21737288
COLO205 Cytotoxicity assay 48 hrs Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.13 μM. 21737288
DWD Cytotoxicity assay 48 hrs Cytotoxicity against human DWD cells after 48 hrs by sulforhodamine B assay, GI50 = 0.6 μM. 21737288
Gurav Cytotoxicity assay 48 hrs Cytotoxicity against human Gurav cells after 48 hrs by sulforhodamine B assay, GI50 = 0.5 μM. 21737288
HOP62 Cytotoxicity assay 48 hrs Cytotoxicity against human HOP62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.8 μM. 21737288
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.1 μM. 21737288
ZR-75-1 Cytotoxicity assay 48 hrs Cytotoxicity against human ZR-75-1 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.2 μM. 21737288
CCRF-CEM Antiproliferative assay 96 hrs Antiproliferative activity against human CCRF-CEM cells after 96 hrs by MTT assay, CC50 = 0.09 μM. 21741130
CCRF-SB Antiproliferative assay 96 hrs Antiproliferative activity against human CCRF-SB cells after 96 hrs by MTT assay, CC50 = 0.1 μM. 21741130
DU145 Antiproliferative assay 96 hrs Antiproliferative activity against human DU145 cells after 96 hrs by MTT assay, CC50 = 0.4 μM. 21741130
HepG2 Antiproliferative assay 96 hrs Antiproliferative activity against human HepG2 cells after 96 hrs by MTT assay, CC50 = 0.7 μM. 21741130
MCF7 Antiproliferative assay 96 hrs Antiproliferative activity against human MCF7 cells after 96 hrs by MTT assay, CC50 = 1 μM. 21741130
SK-MEL-28 Antiproliferative assay 96 hrs Antiproliferative activity against human SK-MEL-28 cells after 96 hrs by MTT assay, CC50 = 1.2 μM. 21741130
SKMES1 Antiproliferative assay 96 hrs Antiproliferative activity against human SKMES1 cells after 96 hrs by MTT assay, CC50 = 0.3 μM. 21741130
WIL2-NS Antiproliferative assay 96 hrs Antiproliferative activity against human WIL2-NS cells after 96 hrs by MTT assay, CC50 = 0.2 μM. 21741130
MT4 Cytotoxicity assay 96 hrs Cytotoxicity against human MT4 cells infected with HTLV-1 after 96 hrs by MTT assay, CC50 = 0.09 μM. 21741130
HeLa Cytotoxicity assay 2 days Cytotoxicity against human HeLa cells after 2 days by MTT assay, IC50 = 6.27 μM. 21821321
K562 Cytotoxicity assay 2 days Cytotoxicity against human K562 cells after 2 days by MTT assay, IC50 = 2.11 μM. 21821321
HeLa Cytotoxicity assay 24 hrs Cytotoxicity against human HeLa cells assessed as inhibition of cell viability after 24 hrs by MTT assay, IC50 = 23.33 μM. 21983445
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 24.9 μM. 22041063
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by CCK-8 assay, IC50 = 2.76 μM. 22041063
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by CCK-8 assay, IC50 = 2.85 μM. 22041063
SiHa Cytotoxicity assay 48 hrs Cytotoxicity against human SiHa cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 40.4 μM. 22041063
KB Growth inhibition assay 72 hrs Growth inhibition of human KB cells after 72 hrs by methylene blue assay, IC50 = 1.1 μM. 22060033
KB-S15 Growth inhibition assay 72 hrs Growth inhibition of human KB-S15 cells after 72 hrs by methylene blue assay, IC50 = 3.5 μM. 22060033
KB-VIN10 Growth inhibition assay 72 hrs Growth inhibition of human KB-VIN10 cells after 72 hrs by methylene blue assay, IC50 = 23 μM. 22060033
CCRF-CEM Cytotoxicity assay 72 hrs Cytotoxicity against human CCRF-CEM cells after 72 hrs by MTT assay, GI50 = 12.59 μM. 22104973
HT-29 Cytotoxicity assay 72 hrs Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay, GI50 = 31.62 μM. 22104973
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, GI50 = 19.95 μM. 22104973
THP1 Cytotoxicity assay 48 hrs Cytotoxicity against human THP1 cells after 48 hrs by MTT assay, IC50 = 2.16 μM. 22115593
U937 Cytotoxicity assay 48 hrs Cytotoxicity against human U937 cells after 48 hrs by MTT assay, IC50 = 17.94 μM. 22115593
B16F10 Cytotoxicity assay 48 hrs Cytotoxicity against mouse B16F10 cells after 48 hrs by MTT assay, IC50 = 18.69 μM. 22115593
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells after 72 hrs by sulforhodamine B and MTT assay, IC50 = 0.91 μM. 22119124
K562 Cytotoxicity assay 72 hrs Cytotoxicity against human K562 cells after 72 hrs by sulforhodamine B and MTT assay, IC50 = 5.16 μM. 22119124
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B and MTT assay, IC50 = 0.85 μM. 22119124
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B and MTT assay, IC50 = 1.09 μM. 22119124
A375 Anticancer assay 48 hrs Anticancer activity against human A375 cells after 48 hrs by MTT assay, IC50 = 1.39 μM. 22136907
A549 Anticancer assay 48 hrs Anticancer activity against human A549 cells after 48 hrs by MTT assay, IC50 = 2.34 μM. 22136907
ACHN Anticancer assay 48 hrs Anticancer activity against human ACHN cells after 48 hrs by MTT assay, IC50 = 7.61 μM. 22136907
HT-29 Anticancer assay 48 hrs Anticancer activity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 1.81 μM. 22136907
MCF7 Anticancer assay 48 hrs Anticancer activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 0.68 μM. 22136907
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 24.9 μM. 22244588
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by CCK-8 assay, IC50 = 40.4 μM. 22244588
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells after 48 hrs by CCK-8 assay, IC50 = 2.85 μM. 22244588
SiHa Cytotoxicity assay 48 hrs Cytotoxicity against human SiHa cells after 48 hrs by MTT assay, IC50 = 2.76 μM. 22244588
DU145 Cytotoxicity assay 96 hrs Cytotoxicity against human DU145 cells after 96 hrs, IC50 = 3 μM. 22276775
HepG2 Cytotoxicity assay 96 hrs Cytotoxicity against human HepG2 cells after 96 hrs, IC50 = 4 μM. 22276775
MT4 Cytotoxicity assay 96 hrs Cytotoxicity against human MT4 cells after 96 hrs, IC50 = 0.09 μM. 22276775
DU145 Cytotoxicity assay 2 days Cytotoxicity against human DU145 cells after 2 days, IC50 = 2.94 μM. 22318164
HCT15 Cytotoxicity assay 2 days Cytotoxicity against human HCT15 cells after 2 days, IC50 = 1.33 μM. 22318164
HeLa Cytotoxicity assay 2 days Cytotoxicity against human HeLa cells after 2 days, IC50 = 3.2 μM. 22318164
K562 Cytotoxicity assay 2 days Cytotoxicity against human K562 cells after 2 days, IC50 = 2.09 μM. 22318164
MCF7 Cytotoxicity assay 2 days Cytotoxicity against human MCF7 cells after 2 days, IC50 = 3.25 μM. 22318164
A549 Cytotoxicity assay 2 days Cytotoxicity against human A549 cells after 2 days by MTT assay, IC50 = 9.51 μM. 22325897
HL60 Cytotoxicity assay 2 days Cytotoxicity against human HL60 cells after 2 days by MTT assay, IC50 = 1.83 μM. 22325897
Jurkat Cytotoxicity assay 2 days Cytotoxicity against human Jurkat cells after 2 days by MTT assay, IC50 = 5.35 μM. 22325897
THP1 Cytotoxicity assay 2 days Cytotoxicity against human THP1 cells after 2 days by MTT assay, IC50 = 2.16 μM. 22325897
U937 Cytotoxicity assay 2 days Cytotoxicity against human U937 cells after 2 days by MTT assay, IC50 = 17.94 μM. 22325897
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 23.8 μM. 22342101
Hep3B Cytotoxicity assay 72 hrs Cytotoxicity against human Hep3B cells after 72 hrs by MTT assay, IC50 = 6.7 μM. 22342101
U87 Cytotoxicity assay 72 hrs Cytotoxicity against human U87 cells after 72 hrs by MTT assay, IC50 = 12.4 μM. 22342101
A2780 Growth inhibition assay 48 hrs Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.31 μM. 22364746
A549 Growth inhibition assay 48 hrs Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.08 μM. 22364746
COLO205 Growth inhibition assay 48 hrs Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.13 μM. 22364746
DWD Growth inhibition assay 48 hrs Growth inhibition of human DWD cells after 48 hrs by sulforhodamine B assay, GI50 = 0.62 μM. 22364746
HOP62 Growth inhibition assay 48 hrs Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.8 μM. 22364746
KB Growth inhibition assay 48 hrs Growth inhibition of human KB cells after 48 hrs by sulforhodamine B assay, GI50 = 0.31 μM. 22364746
MCF7 Growth inhibition assay 48 hrs Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.11 μM. 22364746
ZR-75-1 Growth inhibition assay 48 hrs Growth inhibition of human ZR-75-1 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.2 μM. 22364746
Vero Cytotoxicity assay 48 hrs Cytotoxicity against african green monkey Vero cells after 48 hrs by MTT assay, LC50 = 18 μM. 22381050
HEK293 Cytotoxicity assay 48 hrs Cytotoxicity against human HEK293 cells after 48 hrs by MTT assay, LC50 = 28 μM. 22381050
DU145 Cytotoxicity assay 2 days Cytotoxicity against human DU145 cells after 2 days by cell counting kit-8 analysis, IC50 = 1.21 μM. 22503656
HCT15 Cytotoxicity assay 2 days Cytotoxicity against human HCT15 cells after 2 days by cell counting kit-8 analysis, IC50 = 1.17 μM. 22503656
HEK293 Cytotoxicity assay 2 days Cytotoxicity against human HEK293 cells after 2 days by cell counting kit-8 analysis, IC50 = 1.21 μM. 22503656
T47D Cytotoxicity assay 2 days Cytotoxicity against human T47D cells after 2 days by cell counting kit-8 analysis, IC50 = 2.39 μM. 22503656
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 0.48 μM. 22564383
T98G Cytotoxicity assay 48 hrs Cytotoxicity against human T98G cells expressing mutant p53 after 48 hrs by MTT assay, IC50 = 0.46 μM. 22564383
U87 Cytotoxicity assay 48 hrs Cytotoxicity against human U87 cells expressing wild-type p53 after 48 hrs by MTT assay, IC50 = 0.62 μM. 22564383
COLO205 Antiproliferative assay 48 hrs Antiproliferative activity against human COLO205 cells after 48 hrs by MTT assay, IC50 = 0.43 μM. 22578452
HepG2 Antiproliferative assay 48 hrs Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 4.76 μM. 22578452
THP1 Antiproliferative assay 48 hrs Antiproliferative activity against human THP1 cells after 48 hrs by MTT assay, IC50 = 2.16 μM. 22578452
U937 Antiproliferative assay 48 hrs Antiproliferative activity against human U937 cells after 48 hrs by MTT assay, IC50 = 17.96 μM. 22578452
B16F10 Antiproliferative assay 48 hrs Antiproliferative activity against mouse B16F10 cells after 48 hrs by MTT assay, IC50 = 18.71 μM. 22578452
CCRF-CEM Cytotoxicity assay 48 hrs Cytotoxicity against human CCRF-CEM cells assessed as cell viability after 48 hrs by celltiter-blue assay, IC50 = 0.24 μM. 22582991
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells assessed as cell viability after 48 hrs by celltiter-blue assay, IC50 = 0.11 μM. 22582991
K562 Cytotoxicity assay 48 hrs Cytotoxicity against human K562 cells assessed as cell viability after 48 hrs by celltiter-blue assay, IC50 = 2.3 μM. 22582991
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay, GI50 = 3.56 μM. 22682920
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay, TGI = 40.18 μM. 22682920
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells after 48 hrs by SRB assay, GI50 = 0.56 μM. 22682920
TK10 Antiproliferative assay 48 hrs Antiproliferative activity against human TK10 cells after 48 hrs by SRB assay, GI50 = 7.19 μM. 22682920
TK10 Antiproliferative assay 48 hrs Antiproliferative activity against human TK10 cells after 48 hrs by SRB assay, TGI = 49.74 μM. 22682920
UACC62 Antiproliferative assay 48 hrs Antiproliferative activity against human UACC62 cells after 48 hrs by SRB assay, GI50 = 0.89 μM. 22682920
Vero Cytotoxicity assay 72 hrs Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay, IC50 = 31.14 μM. 22687745
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 10.12 μM. 22687745
HepG2 Cytotoxicity assay 72 hrs Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 5.48 μM. 22687745
SGC7901 Cytotoxicity assay 72 hrs Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay, IC50 = 12.09 μM. 22687745
SH-SY5Y Cytotoxicity assay 72 hrs Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay, IC50 = 5.37 μM. 22687745
L929 Cytotoxicity assay 72 hrs Cytotoxicity against mouse L929 cells after 72 hrs by MTT assay, IC50 = 1 μM. 22687745
KBCPT100 Antiproliferative assay 72 hrs Antiproliferative activity against human camptothecin-resistant KBCPT100 cells after 72 hrs by ethylene blue dye assay, IC50 = 0.336 μM. 22698783
KB Antiproliferative assay 72 hrs Antiproliferative activity against human KB cells after 72 hrs by ethylene blue dye assay, IC50 = 0.475 μM. 22698783
KBCPT100 Antiproliferative assay 72 hrs Antiproliferative activity against human partially revertant camptothecin-resistant KBCPT100 cells after 72 hrs by ethylene blue dye assay, IC50 = 0.374 μM. 22698783
DU145 Cytotoxicity assay 72 hrs Cytotoxicity against human DU145 cells after 72 hrs by MTT assay, IC50 = 1.42 μM. 22819942
HCT15 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay, IC50 = 0.28 μM. 22819942
HEK293 Cytotoxicity assay 72 hrs Cytotoxicity against human HEK293 cells after 72 hrs by MTT assay, IC50 = 0.41 μM. 22819942
T47D Cytotoxicity assay 72 hrs Cytotoxicity against human T47D cells after 72 hrs by MTT assay, IC50 = 1.21 μM. 22819942
A549 Antiproliferative assay 72 hrs Antiproliferative activity at human A549 cells after 72 hrs by MTT assay, IC50 = 0.8 μM. 22861499
DMS53 Antiproliferative assay 72 hrs Antiproliferative activity at human DMS53 cells after 72 hrs by MTT assay, IC50 = 1.5 μM. 22861499
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.83 μM. 22889556
TK10 Cytotoxicity assay 48 hrs Cytotoxicity against human TK10 cells after 48 hrs by sulforhodamine B assay, GI50 = 5.89 μM. 22889556
TK10 Cytotoxicity assay 48 hrs Cytotoxicity against human TK10 cells after 48 hrs by sulforhodamine B assay, TGI = 43.33 μM. 22889556
UACC62 Cytotoxicity assay 48 hrs Cytotoxicity against human UACC62 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.41 μM. 22889556
UACC62 Cytotoxicity assay 48 hrs Cytotoxicity against human UACC62 cells after 48 hrs by sulforhodamine B assay, TGI = 4 μM. 22889556
DOGUM Cytotoxicity assay 72 hrs Cytotoxicity against human DOGUM cells after 72 hrs by MTT assay, IC50 = 0.075 μM. 23031590
DOGUM Cytotoxicity assay 72 hrs Cytotoxicity against human etoposide-resistant DOGUM cells after 72 hrs by MTT assay, IC50 = 0.28 μM. 23031590
GUMBUS Cytotoxicity assay 72 hrs Cytotoxicity against human etoposide-resistant GUMBUS cells after 72 hrs by MTT assay, IC50 = 0.57 μM. 23031590
GUMBUS Cytotoxicity assay 72 hrs Cytotoxicity against human GUMBUS cells after 72 hrs by MTT assay, IC50 = 0.042 μM. 23031590
A549 Growth inhibition assay 72 hrs Growth inhibition of human A549 cells after 72 hrs by SRB assay, GI50 = 2.2 μM. 23153810
HT-29 Growth inhibition assay 72 hrs Growth inhibition of human HT-29 cells after 72 hrs by SRB assay, GI50 = 9.4 μM. 23153810
MDA-MB-231 Growth inhibition assay 72 hrs Growth inhibition of human MDA-MB-231 cells after 72 hrs by SRB assay, GI50 = 7.2 μM. 23153810
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 2.8 μM. 23182091
ACHN Cytotoxicity assay 72 hrs Cytotoxicity against human ACHN cells after 72 hrs by MTT assay, IC50 = 7.61 μM. 23182091
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 1.52 μM. 23182091
HT-29 Cytotoxicity assay 72 hrs Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay, IC50 = 1.81 μM. 23182091
B16 Cytotoxicity assay 72 hrs Cytotoxicity against mouse B16 cells after 72 hrs by MTT assay, IC50 = 1.39 μM. 23182091
HeLa Antitumor assay 48 hrs Antitumor activity against human HeLa cells assessed as growth inhibition measured after 48 hrs by MTT assay, IC50 = 8.32 μM. 23313635
HepG2 Antitumor assay 48 hrs Antitumor activity against human HepG2 cells assessed as growth inhibition measured after 48 hrs by MTT assay, IC50 = 9.14 μM. 23313635
Vero Cytotoxicity assay 48 hrs Cytotoxicity against african green monkey Vero cells after 48 hrs by MTT assay, LC50 = 29 μM. 23321564
HEK293 Cytotoxicity assay 48 hrs Cytotoxicity against HEK293 cells after 48 hrs by MTT assay, LC50 = 17 μM. 23321564
BGC832 Cytotoxicity assay 24 hrs Cytotoxicity against human BGC832 cells after 24 hrs by MTT assay, IC50 = 26.85 μM. 23369687
HeLa Cytotoxicity assay 24 hrs Cytotoxicity against human HeLa cells after 24 hrs by MTT assay, IC50 = 17.68 μM. 23369687
K562 Cytotoxicity assay 24 hrs Cytotoxicity against human K562 cells after 24 hrs by MTT assay, IC50 = 2.85 μM. 23369687
AGS Cytotoxicity assay 72 hrs Cytotoxicity against human AGS cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 0.36 μM. 23454511
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 1.8 μM. 23454511
J82 Cytotoxicity assay 72 hrs Cytotoxicity against human J82 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 2.8 μM. 23454511
MRC5 Cytotoxicity assay 72 hrs Cytotoxicity against human MRC5 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 3.9 μM. 23454511
SKMES1 Cytotoxicity assay 72 hrs Cytotoxicity against human SKMES1 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 2.5 μM. 23454511
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by SRB assay, IC50 = 2.58 μM. 23490151
DU145 Cytotoxicity assay 72 hrs Cytotoxicity against human DU145 cells after 72 hrs by SRB assay, IC50 = 2.03 μM. 23490151
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by SRB assay, IC50 = 3.88 μM. 23490151
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 6.41 μM. 23668986
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 3.2 μM. 23711769
HCT8 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT8 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 7.06 μM. 23711769
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 2.91 μM. 23711769
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by CCK-8 assay, IC50 = 1.15 μM. 23711769
HT-29 Cytotoxicity assay 72 hrs Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay, GI50 = 31.62 μM. 23831811
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, GI50 = 19.95 μM. 23831811
A2780 Growth inhibition assay 48 hrs Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay, GI50 = 1.31 μM. 23849207
A549 Growth inhibition assay 48 hrs Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay, GI50 = 3.08 μM. 23849207
COLO205 Growth inhibition assay 48 hrs Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.13 μM. 23849207
DWD Growth inhibition assay 48 hrs Growth inhibition of human DWD cells after 48 hrs by sulforhodamine B assay, GI50 = 0.62 μM. 23849207
Gurav Growth inhibition assay 48 hrs Growth inhibition of human Gurav cells after 48 hrs by sulforhodamine B assay, GI50 = 0.51 μM. 23849207
HOP62 Growth inhibition assay 48 hrs Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.8 μM. 23849207
KB Growth inhibition assay 48 hrs Growth inhibition of human KB cells after 48 hrs by sulforhodamine B assay, GI50 = 0.31 μM. 23849207
MCF7 Growth inhibition assay 48 hrs Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay, GI50 = 2.11 μM. 23849207
SiHa Growth inhibition assay 48 hrs Growth inhibition of human SiHa cells after 48 hrs by sulforhodamine B assay, GI50 = 3.11 μM. 23849207
ZR-75-1 Growth inhibition assay 48 hrs Growth inhibition of human ZR-75-1 cells after 48 hrs by sulforhodamine B assay, GI50 = 0.2 μM. 23849207
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.5 μM. 23865778
U937 Cytotoxicity assay 72 hrs Cytotoxicity against human U937 cells after 72 hrs by MTT assay, IC50 = 1.4 μM. 23865778
H460 Cytotoxicity assay 48 hrs Cytotoxicity against human H460 cells after 48 hrs by MTT assay, IC50 = 1 μM. 23867385
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 5.48 μM. 23867385
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 32.05 μM. 23968711
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 0.33 μM. 23968711
K562 Cytotoxicity assay 48 hrs Cytotoxicity against human K562 cells after 48 hrs by MTT assay, IC50 = 8.45 μM. 23968711
MCF10A Cytotoxicity assay 72 hrs Cytotoxicity against human MCF10A cells after 72 hrs by MTT assay, IC50 = 36.26 μM. 23999041
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay, GI50 = 0.87 μM. 23999041
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 1.2 μM. 23999041
MDA-MB-231 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-231 cells after 48 hrs by SRB assay, GI50 = 1.67 μM. 23999041
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay, IC50 = 1.5 μM. 23999041
A549 Antiproliferative assay 72 hrs Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 14.3 μM. 24012378
CCRF-CEM Antiproliferative assay 72 hrs Antiproliferative activity against human CCRF-CEM cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 1.1 μM. 24012378
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 3.9 μM. 24012378
Jurkat Antiproliferative assay 72 hrs Antiproliferative activity against human Jurkat cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 1.2 μM. 24012378
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 10.9 μM. 24012378
MDA-MB-231 Antiproliferative assay 72 hrs Antiproliferative activity against human MDA-MB-231 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 21.2 μM. 24012378
HEK293 Cytotoxicity assay 2 days Cytotoxicity against HEK293 cells after 2 days by CCK-8 assay, IC50 = 0.72 μM. 24013413
DU145 Cytotoxicity assay 2 days Cytotoxicity against human DU145 cells after 2 days by CCK-8 assay, IC50 = 9.29 μM. 24013413
HCT15 Cytotoxicity assay 2 days Cytotoxicity against human HCT15 cells after 2 days by CCK-8 assay, IC50 = 5.12 μM. 24013413
T47D Cytotoxicity assay 2 days Cytotoxicity against human T47D cells after 2 days by CCK-8 assay, IC50 = 3.42 μM. 24013413
A549 Antiproliferative assay 72 hrs Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 1.71 μM. 24095018
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by MTT assay, IC50 = 0.87 μM. 24095018
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 14.9 μM. 24095019
HCT8 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT8 cells after 48 hrs by MTT assay, IC50 = 6.54 μM. 24095019
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 4.73 μM. 24095019
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 11.52 μM. 24095019
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells assessed as growth inhibition after 72 hrs by methylene blue staining-based assay, IC50 = 1.1 μM. 24106982
KB-S15 Cytotoxicity assay 72 hrs Cytotoxicity against human KB-S15 cells overexpressing P-gp170/MDR assessed as growth inhibition after 72 hrs by methylene blue staining-based assay, IC50 = 3.5 μM. 24106982
KB-VIN10 Cytotoxicity assay 72 hrs Cytotoxicity against human KB-VIN10 cells overexpressing P-gp170/MDR assessed as growth inhibition after 72 hrs by methylene blue staining-based assay, IC50 = 23 μM. 24106982
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 3.2 μM. 24140948
HCT8 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT8 cells after 48 hrs by MTT assay, IC50 = 7.06 μM. 24140948
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 2.91 μM. 24140948
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells after 48 hrs by cell counting kit-8 assay, IC50 = 1.15 μM. 24140948
A549 Growth inhibition assay 72 hrs Growth inhibition of human A549 cells after 72 hrs by MTT assay, IC50 = 2 μM. 24180210
Hs683 Growth inhibition assay 72 hrs Growth inhibition of human Hs683 cells after 72 hrs by MTT assay, IC50 = 2 μM. 24180210
MCF7 Growth inhibition assay 72 hrs Growth inhibition of human MCF7 cells after 72 hrs by MTT assay, IC50 = 4 μM. 24180210
SK-MEL-28 Growth inhibition assay 72 hrs Growth inhibition of human SK-MEL-28 cells after 72 hrs by MTT assay, IC50 = 3 μM. 24180210
U373 Growth inhibition assay 72 hrs Growth inhibition of human U373 cells after 72 hrs by MTT assay, IC50 = 25 μM. 24180210
HBL100 Growth inhibition assay 48 hrs Growth inhibition of human HBL100 cells after 48 hrs by SRB assay, GI50 = 1.4 μM. 24211632
HeLa Growth inhibition assay 48 hrs Growth inhibition of human HeLa cells after 48 hrs by SRB assay, GI50 = 3.3 μM. 24211632
SW1573 Growth inhibition assay 48 hrs Growth inhibition of human SW1573 cells after 48 hrs by SRB assay, GI50 = 15 μM. 24211632
T47D Growth inhibition assay 48 hrs Growth inhibition of human T47D cells after 48 hrs by SRB assay, GI50 = 22 μM. 24211632
WiDr Growth inhibition assay 48 hrs Growth inhibition of human WiDr cells after 48 hrs by SRB assay, GI50 = 23 μM. 24211632
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by MTS assay, IC50 = 1 μM. 24328269
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay, IC50 = 2.58 μM. 24332656
DU145 Cytotoxicity assay 72 hrs Cytotoxicity against human DU145 cells after 72 hrs by sulforhodamine B assay, IC50 = 2.03 μM. 24332656
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B assay, IC50 = 3.88 μM. 24332656
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay relative to untreated control, GI50 = 4.46 μM. 24389510
HT-29 Cytotoxicity assay 72 hrs Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay relative to untreated control, GI50 = 31.62 μM. 24389510
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay relative to untreated control, GI50 = 19.95 μM. 24389510
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells after 72 hrs by MTT assay relative to untreated control, GI50 = 0.63 μM. 24389510
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells after 72 hrs by MTT assay relative to untreated control, TGI = 3.98 μM. 24389510
RWPE1 Cytotoxicity assay 72 hrs Cytotoxicity against human RWPE1 cells after 72 hrs by MTT assay relative to untreated control, GI50 = 0.9 μM. 24389510
RWPE1 Cytotoxicity assay 72 hrs Cytotoxicity against human RWPE1 cells after 72 hrs by MTT assay relative to untreated control, TGI = 4.8 μM. 24389510
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 4.71 μM. 24487188
HT-29 Cytotoxicity assay 48 hrs Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 21.45 μM. 24487188
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 23.9 μM. 24487188
MDA-MB-231 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 24.22 μM. 24487188
ME180 Cytotoxicity assay 48 hrs Cytotoxicity against human ME180 cells after 48 hrs by MTT assay, IC50 = 8.9 μM. 24487188
PC3 Cytotoxicity assay 48 hrs Cytotoxicity against human PC3 cells after 48 hrs by MTT assay, IC50 = 14.4 μM. 24487188
DLD1 Growth inhibition assay 72 hrs Growth inhibition of human DLD1 cells assessed as inhibition of cell viability after 72 hrs by MTT assay, IC50 = 20 μM. 24527835
HeLa Growth inhibition assay 72 hrs Growth inhibition of human HeLa cells assessed as inhibition of cell viability after 72 hrs by MTT assay, IC50 = 16 μM. 24527835
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by SRB assay, IC50 = 2.58 μM. 24553146
DU145 Cytotoxicity assay 72 hrs Cytotoxicity against human DU145 cells after 72 hrs by SRB assay, IC50 = 2.03 μM. 24553146
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by SRB assay, IC50 = 3.88 μM. 24553146
KB Cytotoxicity assay 72 hrs Cytotoxicity against human KB cells after 72 hrs by methylene blue assay, IC50 = 1.5 μM. 24657567
KB-S15 Cytotoxicity assay 72 hrs Cytotoxicity against human vincristine/paclitaxel-resistant KB-S15 cells overexpressing P-gp170 after 72 hrs by methylene blue assay, IC50 = 3.5 μM. 24657567
KB-VIN10 Cytotoxicity assay 72 hrs Cytotoxicity against human vincristine/paclitaxel-resistant KB-VIN10 cells overexpressing P-gp170 after 72 hrs by methylene blue assay, IC50 = 26.4 μM. 24657567
KB-7d Cytotoxicity assay 72 hrs Cytotoxicity against human VP16-resistant KB-7d cells overexpressing MRP after 72 hrs by methylene blue assay, IC50 = 46.1 μM. 24657567
A549 Anticancer assay 48 hrs Anticancer activity against human A549 cells after 48 hrs by MTT assay, IC50 = 2.45 μM. 24721832
ACHN Anticancer assay 48 hrs Anticancer activity against human ACHN cells after 48 hrs by MTT assay, IC50 = 2.04 μM. 24721832
DU145 Anticancer assay 48 hrs Anticancer activity against human DU145 cells after 48 hrs by MTT assay, IC50 = 3.17 μM. 24721832
HeLa Anticancer assay 48 hrs Anticancer activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 2.75 μM. 24721832
HT-29 Anticancer assay 48 hrs Anticancer activity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 1.47 μM. 24721832
BGC823 Cytotoxicity assay 48 hrs Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay, IC50 = 30.74 μM. 24775914
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 15.32 μM. 24775914
HL-7702 Cytotoxicity assay 48 hrs Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay, IC50 = 24.61 μM. 24775914
H460 Antiproliferative assay 72 hrs Antiproliferative activity against human H460 cells after 72 hrs by MTT assay, IC50 = 0.1 μM. 24780599
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 5 μM. 24780599
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 1 μM. 24780599
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 30.16 μM. 24836071
MOLT3 Cytotoxicity assay 48 hrs Cytotoxicity against human MOLT3 cells after 48 hrs by MTT assay, IC50 = 0.051 μM. 24836071
EPG85-257P Antiproliferative assay 5 days Antiproliferative activity against human EPG85-257P cells after 5 days by sulforhodamine B assay, IC50 = 0.105 μM. 24864039
EPG85-257RD Antiproliferative assay 5 days Antiproliferative activity against human EPG85-257RD cells after 5 days by sulforhodamine B assay, IC50 = 6.2 μM. 24864039
EPG85-257RN Antiproliferative assay 5 days Antiproliferative activity against human EPG85-257RN cells after 5 days by sulforhodamine B assay, IC50 = 1.55 μM. 24864039
EPP85-181P Antiproliferative assay 5 days Antiproliferative activity against human EPP85-181P cells after 5 days by sulforhodamine B assay, IC50 = 0.58 μM. 24864039
EPP85-181RN Antiproliferative assay 5 days Antiproliferative activity against human EPP85-181RN cells after 5 days by sulforhodamine B assay, IC50 = 4.5 μM. 24864039
HT-29 Antiproliferative assay 5 days Antiproliferative activity against human HT-29 cells after 5 days by sulforhodamine B assay, IC50 = 2.3 μM. 24864039
HT-29RD Antiproliferative assay 5 days Antiproliferative activity against human HT-29RD cells after 5 days by sulforhodamine B assay, IC50 = 26 μM. 24864039
HT-29RN Antiproliferative assay 5 days Antiproliferative activity against human HT-29RN cells after 5 days by sulforhodamine B assay, IC50 = 35 μM. 24864039
DU145 Cytotoxicity assay 2 days Cytotoxicity against human DU145 cells after 2 days, IC50 = 13.85 μM. 24904965
HCT15 Cytotoxicity assay 2 days Cytotoxicity against human HCT15 cells after 2 days, IC50 = 9.45 μM. 24904965
MCF10A Cytotoxicity assay 2 days Cytotoxicity against human MCF10A cells after 2 days, IC50 = 12.23 μM. 24904965
T47D Cytotoxicity assay 2 days Cytotoxicity against human T47D cells after 2 days, IC50 = 2.57 μM. 24904965
A549 Growth inhibition assay 72 hrs Growth inhibition of human A549 cells after 72 hrs by MTT assay, IC50 = 0.1 μM. 24950030
Hs683 Growth inhibition assay 72 hrs Growth inhibition of human Hs683 cells after 72 hrs by MTT assay, IC50 = 1 μM. 24950030
MCF7 Growth inhibition assay 72 hrs Growth inhibition of human MCF7 cells after 72 hrs by MTT assay, IC50 = 17 μM. 24950030
PC3 Growth inhibition assay 72 hrs Growth inhibition of human PC3 cells after 72 hrs by MTT assay, IC50 = 2 μM. 24950030
SK-MEL-28 Growth inhibition assay 72 hrs Growth inhibition of human SK-MEL-28 cells after 72 hrs by MTT assay, IC50 = 1 μM. 24950030
U373 Growth inhibition assay 72 hrs Growth inhibition of human U373 cells after 72 hrs by MTT assay, IC50 = 7 μM. 24950030
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells after 72 hrs by MTT assay, IC50 = 0.6 μM. 25014747
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 20.389 μM. 25019480
MOLT3 Cytotoxicity assay 48 hrs Cytotoxicity against human MOLT3 cells after 48 hrs by MTT assay, IC50 = 0.051 μM. 25019480
HEK293 Cytotoxicity assay 4 days Cytotoxicity against HEK293 cells after 4 days by CCK-8 assay, IC50 = 1.04 μM. 25062006
DU145 Cytotoxicity assay 4 days Cytotoxicity against human DU145 cells after 4 days by CCK-8 assay, IC50 = 0.001 μM. 25062006
HCT15 Cytotoxicity assay 4 days Cytotoxicity against human HCT15 cells after 4 days by CCK-8 assay, IC50 = 7.74 μM. 25062006
T47D Cytotoxicity assay 4 days Cytotoxicity against human T47D cells after 4 days by CCK-8 assay, IC50 = 8.74 μM. 25062006
Vero Cytotoxicity assay 48 hrs Cytotoxicity against african green monkey Vero cells after 48 hrs by MTT assay, LC50 = 28 μM. 25078313
HEK293 Cytotoxicity assay 48 hrs Cytotoxicity against HEK293 cells after 48 hrs by MTT assay, LC50 = 18 μM. 25078313
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 6.27 μM. 25113878
K562 Cytotoxicity assay 48 hrs Cytotoxicity against human K562 cells after 48 hrs by MTT assay, IC50 = 3.39 μM. 25113878
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay, GI50 = 0.62 μM. 25131956
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 48 hrs by SRB assay, GI50 = 0.25 μM. 25131956
MIAPaCa2 Antiproliferative assay 48 hrs Antiproliferative activity against human MIAPaCa2 cells assessed as growth inhibition after 48 hrs by SRB assay, GI50 = 1.1 μM. 25131956
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay, IC50 = 13.78 μM. 25240702
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by sulforhodamine B assay, IC50 = 4.36 μM. 25240702
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells after 72 hrs by sulforhodamine B assay, IC50 = 3.67 μM. 25240702
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by MTT assay, IC50 = 9.3 μM. 25402632
HCT15 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay, IC50 = 4.6 μM. 25402632
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 3.4 μM. 25402632
HepG2 Cytotoxicity assay 72 hrs Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay, IC50 = 3.6 μM. 25402632
U373 Cytotoxicity assay 72 hrs Cytotoxicity against human U373 cells after 72 hrs by MTT assay, IC50 = 8.5 μM. 25402632
ZR-7530 Cytotoxicity assay 72 hrs Cytotoxicity against human ZR-7530 cells after 72 hrs by MTT assay, IC50 = 2.5 μM. 25402632
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 4.71 μM. 25453799
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 23.9 μM. 25453799
ME180 Cytotoxicity assay 72 hrs Cytotoxicity against human ME180 cells after 72 hrs by MTT assay, IC50 = 8.9 μM. 25453799
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells after 72 hrs by MTT assay, IC50 = 14.4 μM. 25453799
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 10.12 μM. 25462233
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 5.48 μM. 25462233
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by Alamar Blue assay, IC50 = 2.87 μM. 25466187
L6 Cytotoxicity assay 71.5 hrs Cytotoxicity against rat L6 cells after 71.5 hrs by Presto Blue assay, IC50 = 18.99 μM. 25466187
DU145 Cytotoxicity assay 2 days Cytotoxicity against human DU145 cells after 2 days by CCK-8 assay, IC50 = 0.5 μM. 25481396
HCT15 Cytotoxicity assay 2 days Cytotoxicity against human HCT15 cells after 2 days by CCK-8 assay, IC50 = 1.1 μM. 25481396
HeLa Cytotoxicity assay 2 days Cytotoxicity against human HeLa cells after 2 days by CCK-8 assay, IC50 = 1.26 μM. 25481396
MCF7 Cytotoxicity assay 2 days Cytotoxicity against human MCF7 cells after 2 days by CCK-8 assay, IC50 = 0.73 μM. 25481396
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay, IC50 = 0.8 μM. 25495422
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells after 72 hrs by sulforhodamine B assay, IC50 = 1.9 μM. 25495422
K562 Cytotoxicity assay 72 hrs Cytotoxicity against human K562 cells after 72 hrs by sulforhodamine B assay, IC50 = 3.1 μM. 25495422
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells after 72 hrs by sulforhodamine B assay, IC50 = 10.6 μM. 25495422
SKHEP1 Cytotoxicity assay 72 hrs Cytotoxicity against human SKHEP1 cells after 72 hrs by sulforhodamine B assay, IC50 = 1.1 μM. 25495422
SNU638 Cytotoxicity assay 72 hrs Cytotoxicity against human SNU638 cells after 72 hrs by sulforhodamine B assay, IC50 = 0.5 μM. 25495422
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 8.91 μM. 25599951
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 0.54 μM. 25599951
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 0.06 μM. 25599951
K562 Cytotoxicity assay 48 hrs Cytotoxicity against human K562 cells after 48 hrs by MTT assay, IC50 = 1.64 μM. 25599951
A549 Anticancer assay 48 hrs Anticancer activity against human A549 cells after 48 hrs by MTT assay, IC50 = 3.01 μM. 25615796
DU145 Anticancer assay 48 hrs Anticancer activity against human DU145 cells after 48 hrs by MTT assay, IC50 = 1.98 μM. 25615796
HeLa Anticancer assay 48 hrs Anticancer activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 3.23 μM. 25615796
HepG2 Anticancer assay 48 hrs Anticancer activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 2.45 μM. 25615796
MCF7 Anticancer assay 48 hrs Anticancer activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 2.69 μM. 25615796
HepG2 Cytotoxicity assay 72 hrs Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT colorimetric assay, IC50 = 1.4 μM. 25644672
MDA-MB-468 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 72 hrs by MTT colorimetric assay, IC50 = 6.69 μM. 25644672
THP1 Cytotoxicity assay 72 hrs Cytotoxicity against human THP1 cells assessed as reduction in cell viability after 72 hrs by MTT colorimetric assay, IC50 = 1.82 μM. 25644672
U937 Cytotoxicity assay 72 hrs Cytotoxicity against human U937 cells assessed as reduction in cell viability after 72 hrs by MTT colorimetric assay, IC50 = 1.1 μM. 25644672
EL4 Cytotoxicity assay 72 hrs Cytotoxicity against mouse EL4 cells assessed as reduction in cell viability after 72 hrs by MTT colorimetric assay, IC50 = 4.9 μM. 25644672
N9 Cytotoxicity assay 72 hrs Cytotoxicity against mouse N9 cells assessed as reduction in cell viability after 72 hrs by MTT colorimetric assay, IC50 = 1.95 μM. 25644672
RAW264.7 Cytotoxicity assay 72 hrs Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability after 72 hrs by MTT colorimetric assay, IC50 = 0.82 μM. 25644672
S17 Cytotoxicity assay 72 hrs Cytotoxicity against mouse S17 cells assessed as reduction in cell viability after 72 hrs by MTT colorimetric assay, IC50 = 10.4 μM. 25644672
A549 Antiproliferative assay 3 days Antiproliferative activity against human A549 cells after 3 days by sulforhodamine B assay, IC50 = 0.8 μM. 25700232
HCT116 Antiproliferative assay 3 days Antiproliferative activity against human HCT116 cells after 3 days by sulforhodamine B assay, IC50 = 1.9 μM. 25700232
K562 Antiproliferative assay 3 days Antiproliferative activity against human K562 cells after 3 days by sulforhodamine B assay, IC50 = 3.1 μM. 25700232
MDA-MB-231 Antiproliferative assay 3 days Antiproliferative activity against human MDA-MB-231 cells after 3 days by sulforhodamine B assay, IC50 = 11 μM. 25700232
SKHEP1 Antiproliferative assay 3 days Antiproliferative activity against human SKHEP1 cells after 3 days by sulforhodamine B assay, IC50 = 1.1 μM. 25700232
SNU638 Antiproliferative assay 3 days Antiproliferative activity against human SNU638 cells after 3 days by sulforhodamine B assay, IC50 = 0.5 μM. 25700232
A549 Anticancer assay 48 hrs Anticancer activity against human A549 cells after 48 hrs by MTT assay, IC50 = 11.92 μM. 25744190
HL60 Anticancer assay 48 hrs Anticancer activity against human HL60 cells after 48 hrs by MTT assay, IC50 = 0.31 μM. 25744190
MCF7 Anticancer assay 48 hrs Anticancer activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 32.82 μM. 25744190
SMMC7721 Anticancer assay 48 hrs Anticancer activity against human SMMC7721 cells after 48 hrs by MTT assay, IC50 = 8.12 μM. 25744190
SW480 Anticancer assay 48 hrs Anticancer activity against human SW480 cells after 48 hrs by MTT assay, IC50 = 17.11 μM. 25744190
CCRF-CEM Cytotoxicity assay 72 hrs Cytotoxicity against human CCRF-CEM cells after 72 hrs by MTT assay, GI50 = 1.6 μM. 25792142
HT-29 Cytotoxicity assay 72 hrs Cytotoxicity against human HT-29 cells after 72 hrs by MTT assay, GI50 = 31.6 μM. 25792142
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay, GI50 = 19.9 μM. 25792142
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells after 72 hrs by MTT assay, GI50 = 0.6 μM. 25792142
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells after 72 hrs by MTT assay, TGI = 4 μM. 25792142
DU145 Antiproliferative assay 72 hrs Antiproliferative activity against human DU145 cells assessed as cell viability incubated for 72 hrs by MTT assay, IC50 = 0.4 μM. 25799376
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells assessed as cell viability incubated for 72 hrs by MTT assay, IC50 = 4.33 μM. 25799376
U937 Cytotoxicity assay 24 hrs Cytotoxicity against human U937 cells after 24 hrs by MTT assay, IC50 = 1.5 μM. 25800433
MDA-MB-435 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-435 cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 2.81 μM. 25800514
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by trypan blue staining-based hemocytometric analysis, GI50 = 0.4 μM. 25874335
HBL100 Antiproliferative assay 48 hrs Antiproliferative activity against human HBL100 cells after 48 hrs incubation by SRB assay, GI50 = 1.9 μM. 25899335
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells after 48 hrs incubation by SRB assay, GI50 = 2 μM. 25899335
SW1573 Antiproliferative assay 48 hrs Antiproliferative activity against human SW1573 cells after 48 hrs incubation by SRB assay, GI50 = 3 μM. 25899335
T47D Antiproliferative assay 48 hrs Antiproliferative activity against human T47D cells after 48 hrs incubation by SRB assay, GI50 = 15 μM. 25899335
WiDr Antiproliferative assay 48 hrs Antiproliferative activity against human WiDr cells after 48 hrs incubation by SRB assay, GI50 = 26 μM. 25899335
K/VP.5 Cytotoxicity assay 72 hrs Cytotoxicity against etoposide-resistant human K/VP.5 cells assessed as cell growth inhibition after 72 hrs by MTS assay, IC50 = 2.5 μM. 25922181
K562 Cytotoxicity assay 72 hrs Cytotoxicity against human K562 cells assessed as cell growth inhibition after 72 hrs by MTS assay, IC50 = 0.163 μM. 25922181
DU145 Cytotoxicity assay 4 days Cytotoxicity against human DU145 cells measured on day 4 by CCK8 assay, IC50 = 2.09 μM. 25936262
HCT15 Cytotoxicity assay 4 days Cytotoxicity against human HCT15 cells measured on day 4 by CCK8 assay, IC50 = 18.87 μM. 25936262
HeLa Cytotoxicity assay 4 days Cytotoxicity against human HeLa cells measured on day 4 by CCK8 assay, IC50 = 7.32 μM. 25936262
T47D Cytotoxicity assay 4 days Cytotoxicity against human T47D cells measured on day 4 by CCK8 assay, IC50 = 13.7 μM. 25936262
NALM6 Cytotoxicity assay 5 days Cytotoxicity against human NALM6 cells expressing 50% TOP2A assessed as growth inhibition after 5 days by XTT assay, IC50 = 0.234 μM. 25945730
NALM6 Cytotoxicity assay 5 days Cytotoxicity against TOP2B double knockout human NALM6 cells assessed as growth inhibition after 5 days by XTT assay, IC50 = 0.182 μM. 25945730
NALM6 Cytotoxicity assay 5 days Cytotoxicity against wild type human NALM6 cells assessed as growth inhibition after 5 days by XTT assay, IC50 = 0.134 μM. 25945730
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by sulforhodamine B assay, IC50 = 0.4 μM. 26010585
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation after 72 hrs by sulforhodamine B assay, IC50 = 1.9 μM. 26010585
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells assessed as inhibition of cell proliferation after 72 hrs by sulforhodamine B assay, IC50 = 7.7 μM. 26010585
SKHEP1 Cytotoxicity assay 72 hrs Cytotoxicity against human SKHEP1 cells assessed as inhibition of cell proliferation after 72 hrs by sulforhodamine B assay, IC50 = 2.8 μM. 26010585
SNU638 Cytotoxicity assay 72 hrs Cytotoxicity against human SNU638 cells assessed as inhibition of cell proliferation after 72 hrs by sulforhodamine B assay, IC50 = 0.3 μM. 26010585
DU145 Cytotoxicity assay 2 to 4 days Cytotoxicity against human DU145 cells incubated from day 2 to day 4 by CCK8 assay, IC50 = 0.5 μM. 26022080
HCT15 Cytotoxicity assay 2 to 4 days Cytotoxicity against human HCT15 cells incubated from day 2 to day 4 by CCK8 assay, IC50 = 1.1 μM. 26022080
HeLa Cytotoxicity assay 2 to 4 days Cytotoxicity against human HeLa cells incubated from day 2 to day 4 by CCK8 assay, IC50 = 1.41 μM. 26022080
T47D Cytotoxicity assay 2 to 4 days Cytotoxicity against human T47D cells incubated from day 2 to day 4 by CCK8 assay, IC50 = 0.7 μM. 26022080
KB Antiproliferative assay 72 hrs Antiproliferative activity against human KB cells after 72 hrs by methylene blue assay, IC50 = 1.5 μM. 26160020
KB-7d Antiproliferative assay 72 hrs Antiproliferative activity against human KB-7d cells expressing MRP after 72 hrs by methylene blue assay, IC50 = 46.1 μM. 26160020
KB-S15 Antiproliferative assay 72 hrs Antiproliferative activity against human KB-S15 cells expressing P-gp170/MDR after 72 hrs by methylene blue assay, IC50 = 3.5 μM. 26160020
KB-VIN10 Antiproliferative assay 72 hrs Antiproliferative activity against human KB-VIN10 cells expressing P-gp170/MDR after 72 hrs by methylene blue assay, IC50 = 26.4 μM. 26160020
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by Hoechst assay, IC50 = 0.48 μM. 26225905
DLD1 Cytotoxicity assay 48 hrs Cytotoxicity against human DLD1 cells assessed as inhibition of cell growth incubated for 48 hrs by Hoechst assay, IC50 = 3.3 μM. 26225905
HepG2 Antiproliferative assay 72 hrs Antiproliferative activity against human HepG2 cells after 72 hrs by SRB assay, IC50 = 30 μM. 26291037
MDA-MB-231 Antiproliferative assay 72 hrs Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by SRB assay, IC50 = 3.6 μM. 26291037
MDA-MB-435 Antiproliferative assay 72 hrs Antiproliferative activity against human MDA-MB-435 cells after 72 hrs by SRB assay, IC50 = 1.7 μM. 26291037
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells after 72 hrs by SRB assay, IC50 = 1 μM. 26291037
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 38.5 μM. 26292628
DU145 Cytotoxicity assay 48 hrs Cytotoxicity against human DU145 cells after 48 hrs by MTT assay, IC50 = 5.21 μM. 26292628
HGC Cytotoxicity assay 48 hrs Cytotoxicity against human HGC cells after 48 hrs by MTT assay, IC50 = 10.9 μM. 26292628
MDA-MB-231 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 49.35 μM. 26292628
RWPE1 Cytotoxicity assay 48 hrs Cytotoxicity against human RWPE1 cells after 48 hrs by MTT assay, IC50 = 27.64 μM. 26292628
HCT15 Cytotoxicity assay 2 days Cytotoxicity against human HCT15 cells measured after 2 days by MTT assay, IC50 = 5.54 μM. 26334499
HeLa Cytotoxicity assay 2 days Cytotoxicity against human HeLa cells measured after 2 days by MTT assay, IC50 = 7.6 μM. 26334499
T47D Cytotoxicity assay 2 days Cytotoxicity against human T47D cells measured after 2 days by MTT assay, IC50 = 9.28 μM. 26334499
GBM2 Antiproliferative assay 72 hrs Antiproliferative activity against human GBM2 cells assessed as reduction in cell viability incubated for 72 hrs by WST-1 method, IC50 = 1.1 μM. 26355532
DU145 Cytotoxicity assay 2 days Cytotoxicity against human DU145 cells after 2 days by CCK8 assay, IC50 = 13.1 μM. 26361737
HCT15 Cytotoxicity assay 2 days Cytotoxicity against human HCT15 cells after 2 days by CCK8 assay, IC50 = 2.6 μM. 26361737
MCF10A Cytotoxicity assay 2 days Cytotoxicity against human MCF10A cells after 2 days by CCK8 assay, IC50 = 10.14 μM. 26361737
T47D Cytotoxicity assay 2 days Cytotoxicity against human T47D cells after 2 days by CCK8 assay, IC50 = 0.94 μM. 26361737
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 33.98 μM. 26397393
MOLT3 Cytotoxicity assay 48 hrs Cytotoxicity against human MOLT3 cells after 48 hrs by XTT assay, IC50 = 0.041 μM. 26397393
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by resazurin assay, IC50 = 1.7 μM. 26592897
DLD1 Cytotoxicity assay 48 hrs Cytotoxicity against human DLD1 cells assessed as growth inhibition after 48 hrs by resazurin assay, IC50 = 2 μM. 26592897
A549 Antiproliferative assay 24 to 72 hrs Antiproliferative activity against human A549 cells after 24 to 72 hrs by SRB assay, IC50 = 0.8 μM. 26595875
CAKI-1 Antiproliferative assay 24 to 72 hrs Antiproliferative activity against human CAKI-1 cells after 24 to 72 hrs by SRB assay, IC50 = 1.1 μM. 26595875
HCT116 Antiproliferative assay 24 to 72 hrs Antiproliferative activity against human HCT116 cells after 24 to 72 hrs by SRB assay, IC50 = 3.3 μM. 26595875
HCT116 Antiproliferative assay 48 hrs Antiproliferative activity against human HCT116 cells assessed as cell viability after 48 hrs by SRB assay, IC50 = 2.3 μM. 26595875
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by SRB assay, IC50 = 0.3 μM. 26595875
K562 Antiproliferative assay 24 to 72 hrs Antiproliferative activity against human K562 cells after 24 to 72 hrs by SRB assay, IC50 = 6.7 μM. 26595875
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against p53-expressing human HCT116 cells assessed as cell viability after 72 hrs by SRB assay, IC50 = 1.1 μM. 26595875
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against p53-null human HCT116 cells assessed as cell viability after 72 hrs by SRB assay, IC50 = 3.1 μM. 26595875
A549 Antiproliferative assay 72 hrs Antiproliferative activity against human A549 cells assessed as growth inhibition after 72 hrs by CCK-8 assay, IC50 = 2.675 μM. 26615886
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells assessed as growth inhibition after 72 hrs by CCK-8 assay, IC50 = 1.605 μM. 26615886
HepG2 Antiproliferative assay 72 hrs Antiproliferative activity against human HepG2 cells assessed as growth inhibition after 72 hrs by CCK-8 assay, IC50 = 1.748 μM. 26615886
K562 Antiproliferative assay 72 hrs Antiproliferative activity against human K562 cells assessed as growth inhibition after 72 hrs by CCK-8 assay, IC50 = 0.413 μM. 26615886
K562/ADR Antiproliferative assay 72 hrs Antiproliferative activity against human K562/ADR cells assessed as growth inhibition after 72 hrs by CCK-8 assay, IC50 = 2.025 μM. 26615886
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by SRB assay, IC50 = 26.1 μM. 26618211
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells assessed as cell viability after 72 hrs by SRB assay, IC50 = 3.2 μM. 26618211
MDA-MB-231 Antiproliferative assay 72 hrs Antiproliferative activity against human MDA-MB-231 cells assessed as cell viability after 72 hrs by SRB assay, IC50 = 4.2 μM. 26618211
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 6.74 μM. 26649766
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 32.45 μM. 26649766
HL60 Antiproliferative assay 48 hrs Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay, IC50 = 0.16 μM. 26649766
HL60/MX2 Antiproliferative assay 48 hrs Antiproliferative activity against human HL60/MX2 cells after 48 hrs by MTT assay, IC50 = 9.02 μM. 26649766
K562 Antiproliferative assay 48 hrs Antiproliferative activity against human K562 cells after 48 hrs by MTT assay, IC50 = 0.51 μM. 26649766
MDA-MB-201 Antiproliferative assay 48 hrs Antiproliferative activity against human MDA-MB-201 cells after 48 hrs by MTT assay, IC50 = 31.33 μM. 26649766
Raji Antiproliferative assay 48 hrs Antiproliferative activity against human Raji cells after 48 hrs by MTT assay, IC50 = 1.68 μM. 26649766
HEK293 Cytotoxicity assay 48 hrs Cytotoxicity against HEK293 cells after 48 hrs by MTT assay, IC50 = 0.69 μM. 26649766
GM07492A Cytotoxicity assay 24 hrs Cytotoxicity against human GM07492A cells assessed as cell growth inhibition after 24 hrs by XTT assay, IC50 = 1.2 μM. 26649907
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by SRB assay, IC50 = 1.74 μM. 26706168
HCT15 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT15 cells after 48 hrs by SRB assay, IC50 = 2.95 μM. 26706168
SK-MEL-2 Cytotoxicity assay 48 hrs Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay, IC50 = 1.33 μM. 26706168
SKOV3 Cytotoxicity assay 48 hrs Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay, IC50 = 1.96 μM. 26706168
HT-29 Antiproliferative assay 72 hrs Antiproliferative activity against human HT-29 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay, IC50 = 2.2 μM. 26731300
MCF7 Antiproliferative assay 96 hrs Antiproliferative activity against human MCF7 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay, IC50 = 0.8 μM. 26731300
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay, IC50 = 1.1 μM. 26731300
T84 Antiproliferative assay 96 hrs Antiproliferative activity against human T84 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay, IC50 = 3 μM. 26731300
A375 Cytotoxicity assay 72 hrs Cytotoxicity against human A375 cells assessed as growth inhibition after 72 hrs by ATPlite assay, IC50 = 0.24 μM. 26793989
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by ATPlite assay, IC50 = 0.59 μM. 26793989
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells assessed as growth inhibition after 72 hrs by ATPlite assay, IC50 = 0.86 μM. 26793989
HCT116 Antiproliferative assay 48 hrs Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 1.7 μM. 26804229
HepG2 Antiproliferative assay 48 hrs Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 5.62 μM. 26804229
22Rv1 Antiproliferative assay 96 hrs Antiproliferative activity against human 22Rv1 cells after 96 hrs by propidium iodide-based monolayer assay, IC50 = 0.364 μM. 26854430
MCF7 Antiproliferative assay 96 hrs Antiproliferative activity against human MCF7 cells after 96 hrs by propidium iodide-based monolayer assay, IC50 = 1.264 μM. 26854430
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 23.94 μM. 26873416
HCT8 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT8 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 10.89 μM. 26873416
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 12.12 μM. 26873416
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 27.07 μM. 26873416
WI38 Cytotoxicity assay 48 hrs Cytotoxicity against human WI38 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 35.8 μM. 26873416
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 12.4 μM. 26890115
MDA-MB-231 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 15.7 μM. 26890115
T47D Cytotoxicity assay 48 hrs Cytotoxicity against human T47D cells after 48 hrs by MTT assay, IC50 = 11.8 μM. 26890115
K562 Cytotoxicity assay 48 hrs Cytotoxicity against human K562 cells assessed as reduction in viable cells after 48 hrs by MTT assay, IC50 = 4.39 μM. 26916436
HONE1 Cytotoxicity assay 72 hrs Cytotoxicity against human HONE1 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 1.2 μM. 26920801
HT-29 Cytotoxicity assay 72 hrs Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 2 μM. 26920801
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 2.2 μM. 26920801
P388 Cytotoxicity assay 72 hrs Cytotoxicity against mouse P388 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 1.3 μM. 26920801
HCT15 Cytotoxicity assay 3 days Cytotoxicity against human HCT15 cells after 3 days by CCK8 assay, IC50 = 2.82 μM. 26927425
HeLa Cytotoxicity assay 3 days Cytotoxicity against human HeLa cells after 3 days by CCK8 assay, IC50 = 0.18 μM. 26927425
T47D Cytotoxicity assay 3 days Cytotoxicity against human T47D cells after 3 days by CCK8 assay, IC50 = 1.84 μM. 26927425
DU145 Cytotoxicity assay 48 hrs Cytotoxicity against human DU145 cells after 48 hrs by CCK8 assay, IC50 = 2.09 μM. 26945111
HCT15 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT15 cells after 48 hrs by CCK8 assay, IC50 = 18.87 μM. 26945111
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by CCK8 assay, IC50 = 7.32 μM. 26945111
T47D Cytotoxicity assay 48 hrs Cytotoxicity against human T47D cells after 48 hrs by CCK8 assay, IC50 = 13.7 μM. 26945111
BT474 Antiproliferative assay 72 hrs Antiproliferative activity against human BT474 cells after 72 hrs by CCK8 assay, IC50 = 6.6 μM. 26988802
HCT15 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay, IC50 = 6.9 μM. 26988802
T47D Antiproliferative assay 72 hrs Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay, IC50 = 6.4 μM. 26988802
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 3.82 μM. 27060757
CCRF-CEM Antiproliferative assay 48 hrs Antiproliferative activity against human CCRF-CEM cells after 48 hrs by MTT assay, IC50 = 0.12 μM. 27060757
HCT116 Antiproliferative assay 48 hrs Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay, IC50 = 6.03 μM. 27060757
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 41.21 μM. 27060757
A375 Antiproliferative assay 72 hrs Antiproliferative activity against human A375 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay, IC50 = 0.24 μM. 27096049
A549 Antiproliferative assay 72 hrs Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay, IC50 = 0.59 μM. 27096049
HL60 Antiproliferative assay 72 hrs Antiproliferative activity against human HL60 cells assessed as reduction in cell viability after 72 hrs by ATPlite assay, IC50 = 0.86 μM. 27096049
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 0.5 μM. 27145162
MOLT3 Cytotoxicity assay 72 hrs Cytotoxicity against human MOLT3 cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 0.7 μM. 27145162
HEK293T Cytotoxicity assay 36 hrs Cytotoxicity against HEK293T cells after 36 hrs by MTT assay, IC50 = 11.47 μM. 27262599
A549 Cytotoxicity assay 36 hrs Cytotoxicity against human A549 cells after 36 hrs by MTT assay, IC50 = 8.01 μM. 27262599
HeLa Cytotoxicity assay 36 hrs Cytotoxicity against human HeLa cells after 36 hrs by MTT assay, IC50 = 4.39 μM. 27262599
MCF7 Cytotoxicity assay 36 hrs Cytotoxicity against human MCF7 cells after 36 hrs by MTT assay, IC50 = 1.74 μM. 27262599
HEK293 Anticlonogenic assay 48 hrs Anticlonogenic activity against HEK293 cells assessed as inhibition of colony formation incubated for 48 hrs measured after 6 days by crystal violet staining based assay, LC50 = 20 μM. 27343852
HEK293 Cytotoxicity assay 48 hrs Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by MTT assay, LC50 = 22 μM. 27343852
H460 Antiproliferative assay 72 hrs Antiproliferative activity against human H460 cells after 72 hrs by MTT assay, IC50 = 0.1 μM. 27448912
HCT116 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50 = 5 μM. 27448912
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 1 μM. 27448912
shGFP-fused HMLE Antiproliferative assay 72 hrs Antiproliferative activity against human shGFP-fused HMLE cells after 72 hrs by MTT assay, IC50 = 0.4 μM. 27448912
HCT15 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT15 cells assessed as reduction in cell growth after 72 hrs by CCK8 assay, IC50 = 1.06 μM. 27484510
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells assessed as reduction in cell growth after 72 hrs by CCK8 assay, IC50 = 10.03 μM. 27484510
NCI-N87 Cytotoxicity assay 72 hrs Cytotoxicity against human NCI-N87 cells assessed as reduction in cell growth after 72 hrs by CCK8 assay, IC50 = 1.29 μM. 27484510
T47D Cytotoxicity assay 72 hrs Cytotoxicity against human T47D cells assessed as reduction in cell growth after 72 hrs by CCK8 assay, IC50 = 2.8 μM. 27484510
K562 Antiproliferative assay 72 hrs Antiproliferative activity against human K562 cells measured after 72 hrs by CCK8 assay, IC50 = 0.345 μM. 27484511
K562/ADR Antiproliferative assay 72 hrs Antiproliferative activity against human K562/ADR cells measured after 72 hrs by CCK8 assay, IC50 = 2.211 μM. 27484511
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells measured after 48 hrs by MTT assay, IC50 = 29.7 μM. 27517805
HCT8 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT8 cells measured after 48 hrs by MTT assay, IC50 = 10 μM. 27517805
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells measured after 48 hrs by MTT assay, IC50 = 13.5 μM. 27517805
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells measured after 48 hrs by MTT assay, IC50 = 5.21 μM. 27517805
WI38 Cytotoxicity assay 48 hrs Cytotoxicity against human WI38 cells measured after 48 hrs by MTT assay, IC50 = 17.6 μM. 27517805
HEK293 Cytotoxicity assay 24 hrs Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 24 hrs by MTT assay, IC50 = 0.6 μM. 27533261
H1975-1 Cytotoxicity assay 72 hrs Cytotoxicity against human H1975-1 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay, IC50 = 9.5 μM. 27560280
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by MTT assay, IC50 = 8.2 μM. 27560280
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay, IC50 = 2.1 μM. 27560280
Vero Cytotoxicity assay 72 hrs Cytotoxicity against human Vero cells assessed as reduction in cell viability measured after 72 hrs by MTT assay, IC50 = 1.5 μM. 27560280
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against resistant human HCT116 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay, IC50 = 2.8 μM. 27560280
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells assessed as cell growth inhibition after 72 hrs by MTT assay, IC50 = 0.3 μM. 27598828
HEK293 Antiproliferative assay 72 hrs Antiproliferative activity against HEK293 cells after 72 hrs by CCK8 assay, IC50 = 1.74 μM. 27643560
DU145 Antiproliferative assay 72 hrs Antiproliferative activity against human DU145 cells after 72 hrs by CCK8 assay, IC50 = 0.02 μM. 27643560
HCT15 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay, IC50 = 1.1 μM. 27643560
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay, IC50 = 0.18 μM. 27643560
T47D Antiproliferative assay 72 hrs Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay, IC50 = 1.84 μM. 27643560
DU145 Antiproliferative assay 72 hrs Antiproliferative activity against human DU145 cells measured after 72 hrs by CCK8 assay, IC50 = 2.19 μM. 27654394
HCT15 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT15 cells measured after 72 hrs by CCK8 assay, IC50 = 1.27 μM. 27654394
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells measured after 72 hrs by CCK8 assay, IC50 = 35.55 μM. 27654394
T47D Antiproliferative assay 72 hrs Antiproliferative activity against human T47D cells measured after 72 hrs by CCK8 assay, IC50 = 4.85 μM. 27654394
HBL100 Cytotoxicity assay 48 hrs Cytotoxicity against human HBL100 cells assessed as growth inhibition after 48 hrs by SRB assay, GI50 = 1.4 μM. 27765506
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay, GI50 = 3.3 μM. 27765506
SW1573 Cytotoxicity assay 48 hrs Cytotoxicity against human SW1573 cells assessed as growth inhibition after 48 hrs by SRB assay, GI50 = 15 μM. 27765506
WiDr Cytotoxicity assay 48 hrs Cytotoxicity against human WiDr cells assessed as growth inhibition after 48 hrs by SRB assay, GI50 = 23 μM. 27765506
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 27.41 μM. 27863370
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 13.35 μM. 27863370
T47D Cytotoxicity assay 72 hrs Cytotoxicity against human T47D cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 9.8 μM. 27863370
HEK293T Cytotoxicity assay 48 hrs Cytotoxicity against HEK293T cells assessed as cells growth inhibition after 48 hrs by MTT assay, IC50 = 22 μM. 27994737
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by SRB assay, GI50 = 0.56 μM. 28041801
TK10 Cytotoxicity assay 48 hrs Cytotoxicity against human TK10 cells assessed as cell growth inhibition after 48 hrs by SRB assay, GI50 = 7.19 μM. 28041801
TK10 Cytotoxicity assay 48 hrs Cytotoxicity against human TK10 cells assessed as cell growth inhibition after 48 hrs by SRB assay, TGI = 49.74 μM. 28041801
UACC62 Cytotoxicity assay 48 hrs Cytotoxicity against human UACC62 cells assessed as cell growth inhibition after 48 hrs by SRB assay, GI50 = 0.89 μM. 28041801
THP1 Cytotoxicity assay 72 hrs Cytotoxicity against human THP1 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 1.82 μM. 28062194
U937 Cytotoxicity assay 72 hrs Cytotoxicity against human U937 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 1.1 μM. 28062194
EL4 Cytotoxicity assay 72 hrs Cytotoxicity against mouse EL4 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 4.9 μM. 28062194
S17 Cytotoxicity assay 72 hrs Cytotoxicity against mouse S17 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 10.4 μM. 28062194
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 5.87 μM. 28068602
DU145 Cytotoxicity assay 48 hrs Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 3.1 μM. 28068602
MDA-MB-231 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 20.3 μM. 28068602
PC3 Cytotoxicity assay 48 hrs Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 13.9 μM. 28068602
HCT15 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay, IC50 = 5.4 μM. 28068603
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay, IC50 = 9.1 μM. 28068603
T47D Antiproliferative assay 72 hrs Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay, IC50 = 7 μM. 28068603
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by Cell Titer-Glo assay, EC50 = 15.9 μM. 28080063
HEK293 Antiproliferative assay 48 hrs Antiproliferative activity against HEK293 cells after 48 hrs by SRB assay, IC50 = 7.51 μM. 28094224
DLD1 Antiproliferative assay 48 hrs Antiproliferative activity against human DLD1 cells after 48 hrs by SRB assay, IC50 = 8.11 μM. 28094224
DU145 Antiproliferative assay 48 hrs Antiproliferative activity against human DU145 cells after 48 hrs by SRB assay, IC50 = 10.64 μM. 28094224
FADU Antiproliferative assay 48 hrs Antiproliferative activity against human FADU cells after 48 hrs by SRB assay, IC50 = 16.01 μM. 28094224
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by SRB assay, IC50 = 0.92 μM. 28165740
BT549 Cytotoxicity assay 48 hrs Cytotoxicity against human BT549 cells after 48 hrs by SRB assay, IC50 = 1.24 μM. 28165740
SK-MEL-2 Cytotoxicity assay 48 hrs Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay, IC50 = 1.1 μM. 28165740
SKOV3 Cytotoxicity assay 48 hrs Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay, IC50 = 1.95 μM. 28165740
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 0.83 μM. 28169166
LO2 Cytotoxicity assay 48 hrs Cytotoxicity against human LO2 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 3.78 μM. 28169166
SMMC7721 Cytotoxicity assay 48 hrs Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability after 48 hrs by MTT assay, IC50 = 0.15 μM. 28169166
HCT15 Antiproliferative assay 24 hrs Antiproliferative activity against human HCT15 cells after 24 hrs by WST-1 assay, IC50 = 19.7 μM. 28181805
HeLaS3 Antiproliferative assay 24 hrs Antiproliferative activity against human HeLaS3 cells after 24 hrs by WST-1 assay, IC50 = 43.1 μM. 28181805
HCT15 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay, IC50 = 1.33 μM. 28384547
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay, IC50 = 3.2 μM. 28384547
T47D Antiproliferative assay 72 hrs Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay, IC50 = 3.25 μM. 28384547
Vero Cytotoxicity assay 72 hrs Cytotoxicity against African green monkey Vero cells assessed as decrease in cell viability after 72 hrs by MTT assay, IC50 = 16 μM. 28385594
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 72 hrs by MTT assay, IC50 = 3 μM. 28385594
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by MTT assay, IC50 = 8 μM. 28385594
HL60 Cytotoxicity assay 72 hrs Cytotoxicity against human HL60 cells assessed as decrease in cell viability after 72 hrs by MTT assay, IC50 = 20 μM. 28385594
K562 Cytotoxicity assay 72 hrs Cytotoxicity against human K562 cells assessed as decrease in cell viability after 72 hrs by MTT assay, IC50 = 12 μM. 28385594
A549 Growth inhibition assay 72 hrs Growth inhibition of human A549 cells after 72 hrs by MTT assay, GI50 = 1.7 μM. 28406636
Hs683 Growth inhibition assay 72 hrs Growth inhibition of human Hs683 cells after 72 hrs by MTT assay, GI50 = 1.5 μM. 28406636
MCF7 Growth inhibition assay 72 hrs Growth inhibition of human MCF7 cells after 72 hrs by MTT assay, GI50 = 4 μM. 28406636
SK-MEL-28 Growth inhibition assay 72 hrs Growth inhibition of human SK-MEL-28 cells after 72 hrs by MTT assay, GI50 = 3.2 μM. 28406636
U373 Growth inhibition assay 72 hrs Growth inhibition of human U373 cells after 72 hrs by MTT assay, GI50 = 24.9 μM. 28406636
HeLa Cytotoxicity assay 72 hrs Cytotoxicity against human HeLa cells after 72 hrs by MTT assay, IC50 = 7.89 μM. 28431878
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay, IC50 = 29.27 μM. 28431878
SMMC7721 Cytotoxicity assay 72 hrs Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay, IC50 = 40.44 μM. 28431878
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 19.83 μM. 28462840
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 15.93 μM. 28462840
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 24.01 μM. 28462840
MGC803 Antiproliferative assay 48 hrs Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay, IC50 = 20.91 μM. 28462840
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 14.7 μM. 28512026
HCT8 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT8 cells after 48 hrs by MTT assay, IC50 = 26.3 μM. 28512026
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 24.9 μM. 28512026
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 13.4 μM. 28512026
WI38 Cytotoxicity assay 48 hrs Cytotoxicity against human WI38 cells after 48 hrs by MTT assay, IC50 = 46.9 μM. 28512026
A549 Growth inhibition assay 72 hrs Growth inhibition of human A549 cells incubated for 72 hrs by sulforhodamine B assay, IC50 = 0.3 μM. 28625715
HCT116 Growth inhibition assay 72 hrs Growth inhibition of human HCT116 cells incubated for 72 hrs by sulforhodamine B assay, IC50 = 1.06 μM. 28625715
K562 Growth inhibition assay 72 hrs Growth inhibition of human K562 cells incubated for 72 hrs by sulforhodamine B assay, IC50 = 0.76 μM. 28625715
MDA-MB-231 Growth inhibition assay 72 hrs Growth inhibition of human MDA-MB-231 cells incubated for 72 hrs by sulforhodamine B assay, IC50 = 1.53 μM. 28625715
MRC5 Growth inhibition assay 72 hrs Growth inhibition of human MRC5 cells incubated for 72 hrs by sulforhodamine B assay, IC50 = 11.73 μM. 28625715
SKHEP1 Growth inhibition assay 72 hrs Growth inhibition of human SKHEP1 cells incubated for 72 hrs by sulforhodamine B assay, IC50 = 0.63 μM. 28625715
SNU638 Growth inhibition assay 72 hrs Growth inhibition of human SNU638 cells incubated for 72 hrs by sulforhodamine B assay, IC50 = 1.05 μM. 28625715
HCT15 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT15 cells after 72 hrs by CCK8 assay, IC50 = 9.27 μM. 28633898
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells after 72 hrs by CCK8 assay, IC50 = 4.12 μM. 28633898
T47D Antiproliferative assay 72 hrs Antiproliferative activity against human T47D cells after 72 hrs by CCK8 assay, IC50 = 8.81 μM. 28633898
HeLa Cytotoxicity assay 72 hrs Cytotoxic activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 7.21 μM. 28733083
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxic activity against human MDA-MB-231 cells after 72 hrs by MTT assay, IC50 = 16.27 μM. 28733083
SMMC7721 Cytotoxicity assay 72 hrs Cytotoxic activity against human SMMC7721 cells after 72 hrs by MTT assay, IC50 = 21.03 μM. 28733083
A549 Cytotoxicity assay 24 hrs Cytotoxicity against human A549 cells after 24 hrs by MTT assay, IC50 = 6.21 μM. 28757065
HeLa Cytotoxicity assay 24 hrs Cytotoxicity against human HeLa cells after 24 hrs by MTT assay, IC50 = 1.58 μM. 28757065
HepG2 Cytotoxicity assay 24 hrs Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay, IC50 = 5.52 μM. 28757065
L02 Cytotoxicity assay 24 hrs Cytotoxicity against human L02 cells after 24 hrs by MTT assay, IC50 = 7.75 μM. 28757065
MCF7 Cytotoxicity assay 24 hrs Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay, IC50 = 2.08 μM. 28757065
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by SRB assay, IC50 = 1.1 μM. 28841320
BT549 Cytotoxicity assay 48 hrs Cytotoxicity against human BT549 cells after 48 hrs by SRB assay, IC50 = 1 μM. 28841320
SK-MEL-2 Cytotoxicity assay 48 hrs Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay, IC50 = 0.2 μM. 28841320
SKOV3 Cytotoxicity assay 48 hrs Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay, IC50 = 2.9 μM. 28841320
SK-MEL-1 Cytotoxicity assay 72 hrs Cytotoxicity against human SK-MEL-1 cells assessed as reduction in cell viability after 72 hrs by MTT assay, IC50 = 8 μM. 29032930
A549 Antiproliferative assay 72 hrs Antiproliferative activity against human A549 cells after 72 hrs by MTT assay, IC50 = 1.3 μM. 29077404
DU145 Antiproliferative assay 72 hrs Antiproliferative activity against human DU145 cells after 72 hrs by MTT assay, IC50 = 1 μM. 29077404
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay, IC50 = 2.4 μM. 29077404
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, IC50 = 10.5 μM. 29077404
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells after 48 hrs by SRB assay, GI50 = 1.5 μM. 29129514
HBL100 Antiproliferative assay 48 hrs Antiproliferative activity against human HBL100 cells after 48 hrs by SRB assay, GI50 = 2.3 μM. 29129514
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay, GI50 = 3 μM. 29129514
SW1573 Antiproliferative assay 48 hrs Antiproliferative activity against human SW1573 cells after 48 hrs by SRB assay, GI50 = 15 μM. 29129514
T47D Antiproliferative assay 48 hrs Antiproliferative activity against human T47D cells after 48 hrs by SRB assay, GI50 = 22 μM. 29129514
WiDr Antiproliferative assay 48 hrs Antiproliferative activity against human WiDr cells after 48 hrs by SRB assay, GI50 = 23 μM. 29129514
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as reduction in inhibition of cell growth incubated for 48 hrs by MTT assay, IC50 = 9.1 μM. 29248296
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells assessed as reduction in inhibition of cell growth incubated for 48 hrs by MTT assay, IC50 = 11.2 μM. 29248296
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells assessed as reduction in inhibition of cell growth incubated for 48 hrs by MTT assay, IC50 = 9.2 μM. 29248296
LoVo Cytotoxicity assay 48 hrs Cytotoxicity against human LoVo cells assessed as reduction in inhibition of cell growth incubated for 48 hrs by MTT assay, IC50 = 18.7 μM. 29248296
WI38 Cytotoxicity assay 48 hrs Cytotoxicity against human WI38 cells assessed as reduction in inhibition of cell growth incubated for 48 hrs by MTT assay, IC50 = 25.7 μM. 29248296
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 2.03 μM. 29269253
DU145 Cytotoxicity assay 48 hrs Cytotoxicity against human DU145 cells after 48 hrs by MTT assay, IC50 = 2.03 μM. 29269253
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 2.03 μM. 29269253
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 2.03 μM. 29269253
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 2.27 μM. 29289881
DU145 Cytotoxicity assay 48 hrs Cytotoxicity against human DU145 cells after 48 hrs by MTT assay, IC50 = 1.97 μM. 29289881
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 1.93 μM. 29289881
HT-29 Cytotoxicity assay 48 hrs Cytotoxicity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 1.64 μM. 29289881
MDA-MB-231 Cytotoxicity assay 48 hrs Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay, IC50 = 1.91 μM. 29289881
A549 Antiproliferative assay 48 hrs Antiproliferative activity against human A549 cells after 48 hrs by MTT assay, IC50 = 1.97 μM. 29289884
DU145 Antiproliferative assay 48 hrs Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay, IC50 = 2.35 μM. 29289884
HeLa Antiproliferative assay 48 hrs Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay, IC50 = 2.71 μM. 29289884
HepG2 Antiproliferative assay 48 hrs Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 2.84 μM. 29289884
HT-29 Antiproliferative assay 48 hrs Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay, IC50 = 1.87 μM. 29289884
MCF7 Antiproliferative assay 48 hrs Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay, IC50 = 1.62 μM. 29289884
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 32.61 μM. 29335211
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 22.35 μM. 29335211
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 0.19 μM. 29335211
PC3 Cytotoxicity assay 48 hrs Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by MTT assay, IC50 = 5.73 μM. 29335211
HCT15 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT15 cells incubated for 72 hrs by CCK8 assay, IC50 = 2.94 μM. 29402741
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells incubated for 72 hrs by CCK8 assay, IC50 = 9.21 μM. 29402741
T47D Antiproliferative assay 72 hrs Antiproliferative activity against human T47D cells incubated for 72 hrs by CCK8 assay, IC50 = 0.4 μM. 29402741
HCT15 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT15 cells after 72 hrs by CCK-8 assay, IC50 = 2.45 μM. 29510948
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells after 72 hrs by CCK-8 assay, IC50 = 10.03 μM. 29510948
T47D Antiproliferative assay 72 hrs Antiproliferative activity against human T47D cells after 72 hrs by CCK-8 assay, IC50 = 0.32 μM. 29510948
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 3.25 μM. 29525336
DU145 Cytotoxicity assay 48 hrs Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 2.13 μM. 29525336
HCT116 Cytotoxicity assay 48 hrs Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 2.6 μM. 29525336
HT-29 Cytotoxicity assay 48 hrs Cytotoxicity against human HT-29 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 1.8 μM. 29525336
MCF7 Cytotoxicity assay 48 hrs Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 2.03 μM. 29525336
PC3 Cytotoxicity assay 48 hrs Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay, IC50 = 5.4 μM. 29525336
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 13.71 μM. 29545100
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 32.05 μM. 29545100
HL60 Cytotoxicity assay 48 hrs Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, IC50 = 0.33 μM. 29545100
K562 Cytotoxicity assay 48 hrs Cytotoxicity against human K562 cells after 48 hrs by MTT assay, IC50 = 8.45 μM. 29545100
K562 Cytotoxicity assay 72 hrs Cytotoxicity against human etoposide-sensitive K562 cells after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay, IC50 = 1.22 μM. 29656990
HT-29 Cytotoxicity assay 24 to 72 hrs Cytotoxicity against human HT-29 cells measured after 24 to 72 hrs by SRB assay, IC50 = 15 μM. 29656990
K/VP.5 Cytotoxicity assay 72 hrs Cytotoxicity against human K/VP.5 cells after 72 hrs by CellTiter96 AQueous one solution cell proliferation assay, IC50 = 35.36 μM. 29656990
OVCAR3 Cytotoxicity assay 24 to 72 hrs Cytotoxicity against human OVCAR3 cells measured after 24 to 72 hrs by SRB assay, IC50 = 2.9 μM. 29656990
CCRF-CEM Cytotoxicity assay 72 hrs Cytotoxicity against human CCRF-CEM cells assessed as growth inhibition after 72 hrs by MTT assay, GI50 = 1.26 μM. 29670691
HT-29 Cytotoxicity assay 72 hrs Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by MTT assay, GI50 = 31.62 μM. 29670691
K562 Cytotoxicity assay 72 hrs Cytotoxicity against human K562 cells assessed as growth inhibition after 72 hrs by MTT assay, GI50 = 12.59 μM. 29670691
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay, GI50 = 19.95 μM. 29670691
PC3 Cytotoxicity assay 72 hrs Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay, GI50 = 0.63 μM. 29670691
K562 Antiproliferative assay 72 hrs Antiproliferative activity against human K562 cells after 72 hrs by CCK8 assay, IC50 = 0.764 μM. 29678463
K562/VCR Antiproliferative assay 72 hrs Antiproliferative activity against human K562/VCR cells after 72 hrs by CCK8 assay, IC50 = 11.84 μM. 29678463
HepG2 Cytotoxicity assay 72 hrs Cytotoxicity against human HepG2 cells assessed as reduction in cell proliferation after 72 hrs by MTS assay, IC50 = 20.1 μM. 29778894
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 9.4695 μM. 29886322
L02 Cytotoxicity assay 72 hrs Cytotoxicity against human L02 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 3.4805 μM. 29886322
MCF7 Cytotoxicity assay 72 hrs Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay, IC50 = 4.7165 μM. 29886322
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells after 72 hrs by sulforhodamine B assay, IC50 = 0.72 μM. 29893558
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells after 72 hrs by sulforhodamine B assay, IC50 = 0.68 μM. 29893558
K562 Cytotoxicity assay 72 hrs Cytotoxicity against human K562 cells after 72 hrs by sulforhodamine B assay, IC50 = 1.3 μM. 29893558
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells after 72 hrs by sulforhodamine B assay, IC50 = 4.4 μM. 29893558
SKHEP1 Cytotoxicity assay 72 hrs Cytotoxicity against human SKHEP1 cells after 72 hrs by sulforhodamine B assay, IC50 = 0.93 μM. 29893558
SNU638 Cytotoxicity assay 72 hrs Cytotoxicity against human SNU638 cells after 72 hrs by sulforhodamine B assay, IC50 = 0.43 μM. 29893558
A549 Cytotoxicity assay 72 hrs Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 0.3 μM. 30041947
HCT116 Cytotoxicity assay 72 hrs Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 1.06 μM. 30041947
K562 Cytotoxicity assay 72 hrs Cytotoxicity against human K562 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 0.76 μM. 30041947
MDA-MB-231 Cytotoxicity assay 72 hrs Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 1.53 μM. 30041947
MRC5 Cytotoxicity assay 72 hrs Cytotoxicity against human MRC5 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 11.73 μM. 30041947
SKHEP1 Cytotoxicity assay 72 hrs Cytotoxicity against human SKHEP1 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 0.63 μM. 30041947
SNU638 Cytotoxicity assay 72 hrs Cytotoxicity against human SNU638 cells assessed as growth inhibition after 72 hrs by SRB assay, IC50 = 1.05 μM. 30041947
CCRF-CEM Antiproliferative assay 72 hrs Antiproliferative activity against human CCRF-CEM cells after 72 hrs by MTT assay, GI50 = 1.6 μM. 30071406
HT-29 Antiproliferative assay 72 hrs Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay, GI50 = 31.6 μM. 30071406
MCF7 Antiproliferative assay 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay, GI50 = 19.9 μM. 30071406
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, GI50 = 0.6 μM. 30071406
PC3 Antiproliferative assay 72 hrs Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay, TGI = 4 μM. 30071406
HCT15 Antiproliferative assay 72 hrs Antiproliferative activity against human HCT15 cells after 72 hrs by EZ-CYTOX reagent based assay, IC50 = 2.94 μM. 30262132
HeLa Antiproliferative assay 72 hrs Antiproliferative activity against human HeLa cells after 72 hrs by EZ-CYTOX reagent based assay, IC50 = 9.21 μM. 30262132
T47D Antiproliferative assay 72 hrs Antiproliferative activity against human T47D cells after 72 hrs by EZ-CYTOX reagent based assay, IC50 = 0.4 μM. 30262132
A549 Cytotoxicity assay 48 hrs Cytotoxicity against human A549 cells after 48 hrs by MTT assay, IC50 = 22.5 μM. 30265994
HeLa Cytotoxicity assay 48 hrs Cytotoxicity against human HeLa cells after 48 hrs by MTT assay, IC50 = 21.4 μM. 30265994
HepG2 Cytotoxicity assay 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay, IC50 = 20 μM. 30265994
HL7702 Cytotoxicity assay 48 hrs Cytotoxicity against human HL7702 cells after 48 hrs by MTT assay, IC50 = 24.6 μM. 30265994
MRC5 Cytotoxicity assay 48 hrs Cytotoxicity against human MRC5 cells after 48 hrs by MTT assay, IC50 = 33.5 μM. 30265994
MOLT-3 Growth Inhibition Assay IC50=0.051 ± 0.002 μM 25078311
HepG2 Growth Inhibition Assay IC50=30.16 ± 0.50 μM 25078311
T47D Growth Inhibition Assay IC50=3.18 ± 0.11 μM 25603122
HCT15 Growth Inhibition Assay IC50=0.81 ± 0.01 μM 25603122
DU145 Growth Inhibition Assay IC50=2.28 ± 0.04 μM 25603122
HEK293 Growth Inhibition Assay IC50=7.14 ± 0.36 μM 25603122
SK-N-ASCis24 Growth Inhibition Assay IC50=0.57 ± 0.11 μM 25960282
SK-N-AS Growth Inhibition Assay IC50=0.24 ± 0.03 μM 25960282
KellyCis83 Growth Inhibition Assay IC50=0.16 ± 0.02 μM 25960282
Kelly Growth Inhibition Assay IC50=0.12 ± 0.01 μM 25960282
MIAPACA Growth Inhibition Assay GI50=1.3 ± 0.03 μM 24953821
MCF-7 Growth Inhibition Assay GI50=0.25 ± 0.1 μM 24953821
HeLa Growth Inhibition Assay GI50=0.64 ± 0.4 μM 24953821
HCT116 Cytotoxicity assay Cytotoxicity against HCT116 cells., IC50 = 2.5 μM. 7473578
CCRF CEM Function assay Tested for the inhibitory activity against CCRF CEM T- cell leukemia cells, IC50 = 0.002 μM. 7932571
KB ATCC Function assay 50% reduction in the number of KB ATCC cells, ID50 = 0.32 μM. 8120864
SCLC Cytotoxicity assay Cytotoxicity against human SCLC cells resistant to cisplatin (SCLC/CDDP), IC50 = 1.3 μM. 8258835
HeLa Function assay Tested for inhibition of topoisomerase II isolated from HeLa cells by DNA-cleavage assay, EC50 = 0.81 μM. 8410993
KB Growth inhibition assay Compound concentration required to reduce the exponential growth of KB cells by 50%, CC50 = 0.1 μM. 9767632
MT-4 Growth inhibition assay Compound concentration required to reduce the exponential growth of MT-4 cells by 50%, CC50 = 0.08 μM. 9767632
L1210 Cytotoxicity assay In vitro cytotoxic activity against murine L1210 leukemia cells., IC50 = 0.2 μM. 9804687
HL-60 Cytotoxicity assay Relative cytotoxicity against human promyelocytic leukemia(HL-60) cells, IC50 = 0.367 μM. 10377219
HL-60 Cytotoxicity assay Relative cytotoxicity against human promyelocytic leukemia(HL-60) cells, IC90 = 0.73 μM. 10377219
A549 Function assay GI values against A549 cells (lung cancer), GI50 = 6.30957 μM. 11311065
CAKI-1 Function assay GI values against CAKI-1 cells(renal carcinoma), GI50 = 6.30957 μM. 11311065
KB Function assay GI values against KB cells (nasopharyngeal carcinoma), GI50 = 0.19953 μM. 11311065
HEL Function assay Inhibitory activity against human cytomegalovirus (HCMV) in HEL cells, ED50 = 8.64 μM. 11311065
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by MTT assay, IC50 = 0.5 μM. 11473438
HL60 Cytotoxicity assay Cytotoxicity against human HL60 cells by MTT assay, IC50 = 5.4 μM. 11473438
MCF7 Cytotoxicity assay Cytotoxicity against human MCF7 cells by MTT assay, IC50 = 12.3 μM. 11473438
P388 Cytotoxicity assay Cytotoxicity against mouse P388 cells by MTT assay, IC50 = 0.1 μM. 11473438
HT-29 Cytotoxicity assay Tested for cytotoxicity against Colon carcinoma type HT-29 cell line expressing MDR-1 (-) gene; 35% of cells were affected, IC50 = 10 μM. 11844671
KB Function assay Compound concentration required to reduce the cell proliferation of Wild type and Drug- resistant human nasopharyngeal carcinoma KB cells by 50%, IC50 = 0.6 μM. 12431048
P388 Growth inhibition assay Growth inhibitory activity against murine P388 leukemia cells, IC50 = 0.15 μM. 12620081
HL60 Apoptosis assay In vitro concentration required to induce apoptosis in HL60 cells, AC50 = 0.45 μM. 12877593
HL60R Apoptosis assay In vitro concentration required to induce apoptosis in HL60R cells, AC50 = 15 μM. 12877593
HL60 Function assay In vitro inhibitory concentration against proliferation of HL60 cells, IC50 = 0.123 μM. 12877593
HL60R Function assay In vitro inhibitory concentration against proliferation of HL60R cells, IC50 = 6.5 μM. 12877593
HL60R Function assay In vitro inhibitory concentration against proliferation of HL60R cells along with 5 (uM) verapamil, IC50 = 0.5 μM. 12877593
HL60 Cytotoxicity assay Cytotoxicity against human HL60 cells by MTT assay, IC50 = 0.2 μM. 14738377
KB Cytotoxicity assay Cytotoxicity against human KB cells, ID50 = 0.2 μM. 14987069
KB Cytotoxicity assay Cytotoxicity against human KB cells, LD50 = 3 μM. 14987069
MCF7 Cytotoxicity assay Cytotoxicity against human MCF7 cells, GI50 = 4.36516 μM. 14987069
MOLT4 Cytotoxicity assay Cytotoxicity against human MOLT4 cells, GI50 = 1.02329 μM. 14987069
HeLa Function assay Concentration required to inhibit S phase and G2/M phase in HeLa cells, Concentration = 2 μM. 15026047
HeLa Growth inhibition assay Growth inhibitory concentration of compound was determined against HeLa cells by alamar blue assay, GI50 = 40 μM. 15026047
A549 Function assay Effective dose on human lung carcinoma (A549) cells, ED50 = 3.39 μM. 15914002
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by SRB assay, IC50 = 1.16 μM. 17194596
HCT116 Cytotoxicity assay Cytotoxicity against human HCT116 cells by SRB assay, IC50 = 1.87 μM. 17194596
HL60 Cytotoxicity assay Cytotoxicity against human HL60 cells by SRB assay, IC50 = 0.37 μM. 17194596
HT1080 Cytotoxicity assay Cytotoxicity against human HT1080 cells by SRB assay, IC50 = 0.25 μM. 17194596
SK-MEL-2 Cytotoxicity assay Cytotoxicity against human SK-MEL-2 cells by SRB assay, IC50 = 5.72 μM. 17194596
SK-OV-3 Cytotoxicity assay Cytotoxicity against human SK-OV-3 cells by SRB assay, IC50 = 4.28 μM. 17194596
SNU638 Cytotoxicity assay Cytotoxicity against human SNU638 cells by SRB assay, IC50 = 0.23 μM. 17194596
XF498 Cytotoxicity assay Cytotoxicity against human XF498 cells by SRB assay, IC50 = 3.48 μM. 17194596
HCT116 Cytotoxicity assay Cytotoxicity against human HCT116 cells by XTT assay, IC50 = 1.7 μM. 17368022
MCF7 Cytotoxicity assay Cytotoxicity against human MCF7 cells by XTT assay, IC50 = 35.6 μM. 17368022
MDA-MB468 Cytotoxicity assay Cytotoxicity against human MDA-MB468 cells by XTT assay, IC50 = 13.6 μM. 17368022
mouse astrocyte cells Antiproliferative assay Antiproliferative activity against mouse astrocyte cells by MTT assay, EC50 = 0.433 μM. 17417631
mouse medulloblastoma cells Antiproliferative assay Antiproliferative activity against mouse medulloblastoma cells harboring heterozygous ptch1 gene by MTT assay, EC50 = 0.208 μM. 17417631
mouse neural precursor cells Antiproliferative assay Antiproliferative activity against mouse neural precursor cells by MTT assay, EC50 = 0.34 μM. 17417631
H460 Growth inhibition assay Growth inhibition of human H460 cells by MTT assay, IC50 = 0.2 μM. 17482821
HeLa Growth inhibition assay Growth inhibition of human HeLa cells by MTT assay, IC50 = 2.9 μM. 17482821
MiaPaCa2 Growth inhibition assay Growth inhibition of human MiaPaCa2 cells by MTT assay, IC50 = 15.4 μM. 17482821
SW620 Growth inhibition assay Growth inhibition of human SW620 cells by MTT assay, IC50 = 20 μM. 17482821
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by SRB microtiter plate assay, IC50 = 1.4 μM. 17585747
DU145 Cytotoxicity assay Cytotoxicity against human DU145 cells by SRB microtiter plate assay, IC50 = 2.4 μM. 17585747
KB Cytotoxicity assay Cytotoxicity against human KB cells by SRB microtiter plate assay, IC50 = 4.8 μM. 17585747
ZR751 Cytotoxicity assay Cytotoxicity against human ZR751cells by SRB microtiter plate assay, IC50 = 3.1 μM. 17585747
HL60/MX2 Cytotoxicity assay Cytotoxicity against DNA topoisomerase-2 deficient human HL60/MX2 cells by MTT assay, GI50 = 5.98 μM. 17962028
502713 Cytotoxicity assay Cytotoxicity against human 502713 cells by sulforhodamine B assay, IC50 = 2.42 μM. 17988764
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by sulforhodamine B assay, IC50 = 5.62 μM. 17988764
DU145 Cytotoxicity assay Cytotoxicity against human DU145 cells by sulforhodamine B assay, IC50 = 3.85 μM. 17988764
HCT-15 Cytotoxicity assay Cytotoxicity against human HCT-15 cells by sulforhodamine B assay, IC50 = 1.48 μM. 17988764
HEP2 Cytotoxicity assay Cytotoxicity against human HEP2 cells by sulforhodamine B assay, IC50 = 2.15 μM. 17988764
PC-3 Cytotoxicity assay Cytotoxicity against human PC-3 cells by sulforhodamine B assay, IC50 = 17.4 μM. 17988764
SF295 Cytotoxicity assay Cytotoxicity against human SF295 cells by sulforhodamine B assay, IC50 = 13.3 μM. 17988764
MCF7 Cytotoxicity assay Cytotoxicity against human MCF7 cells by XTT assay, IC50 = 35.6 μM. 18093835
DU145 Cytotoxicity assay Cytotoxicity against human DU145 cells, IC50 = 29.79 μM. 18178085
HCT116 Cytotoxicity assay Cytotoxicity against human HCT116 cells, IC50 = 15.11 μM. 18178085
HeLa Cytotoxicity assay Cytotoxicity against human HeLa cells, IC50 = 18.24 μM. 18178085
HL60 Cytotoxicity assay Cytotoxicity against human HL60 cells, IC50 = 1.44 μM. 18178085
MDA-MB-231 Cytotoxicity assay Cytotoxicity against human MDA-MB-231 cells, IC50 = 16.25 μM. 18178085
NCI-H520 Growth inhibition assay Growth inhibition of human NCI-H520 cells, GI50 = 13.5 μM. 18502124
PC3 Growth inhibition assay Growth inhibition of human PC3 cells, GI50 = 12.5 μM. 18502124
SK-Hep1 Cytotoxicity assay Cytotoxicity against human SK-Hep1 cells by MTT assay, IC50 = 49.6 μM. 18637688
HL60 Cytotoxicity assay Cytotoxicity against human HL60 cells by SRB assay, IC50 = 0.2 μM. 18651771
A549 Cytotoxicity assay Cytotoxicity against human A549 cells assessed as reduction of cell growth by SRB method, IC50 = 9.98 μM. 18782668
KB Cytotoxicity assay Cytotoxicity against human KB cells assessed as reduction of cell growth by SRB method, IC50 = 14.2 μM. 18782668
A375 Cytotoxicity assay Cytotoxicity against human A375 cells by MTT assay, IC50 = 3.92 μM. 19036584
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by MTT assay, IC50 = 9.51 μM. 19036584
HL60 Cytotoxicity assay Cytotoxicity against human HL60 cells by MTT assay, IC50 = 1.83 μM. 19036584
THP1 Cytotoxicity assay Cytotoxicity against human THP1 cells by MTT assay, IC50 = 2.16 μM. 19036584
HCT15 Antiproliferative assay Antiproliferative activity against human HCT15 cells by SRB assay, GI50 = 1.25 μM. 19394218
MESSA Antiproliferative assay Antiproliferative activity against human MESSA cells by SRB assay, GI50 = 0.21 μM. 19394218
HCT15/CLO2 Antiproliferative assay Antiproliferative activity against multidrug resistant human HCT15/CLO2 cells by SRB assay, GI50 = 10.02 μM. 19394218
MES-SA/Dx5 Antiproliferative assay Antiproliferative activity against multidrug resistant human MES-SA/Dx5 cells by SRB assay, GI50 = 9.72 μM. 19394218
A375 Cytotoxicity assay Cytotoxicity against human A375 cells by MTT assay, IC50 = 3.92 μM. 19782567
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by MTT assay, IC50 = 9.51 μM. 19782567
HL60 Cytotoxicity assay Cytotoxicity against human HL60 cells by MTT assay, IC50 = 2.16 μM. 19782567
THP1 Cytotoxicity assay Cytotoxicity against human THP1 cells by MTT assay, IC50 = 1.83 μM. 19782567
H69 Cytotoxicity assay Cytotoxicity against human adriamycin resistant H69 cells, IC50 = 46 μM. 19788270
HeLa Cytotoxicity assay Cytotoxicity against human HeLa cells, IC50 = 0.4 μM. 19788270
HuCCa1 Cytotoxicity assay Cytotoxicity against human HuCCa1 cells, IC50 = 5.1 μM. 19788270
KB Cytotoxicity assay Cytotoxicity against human KB cells, IC50 = 0.5 μM. 19788270
MDA-MB-231 Cytotoxicity assay Cytotoxicity against human MDA-MB-231 cells, IC50 = 0.3 μM. 19788270
T47D Cytotoxicity assay Cytotoxicity against human T47D cells, IC50 = 0.1 μM. 19788270
DU145 Cytotoxicity assay Cytotoxicity against human DU145 cells by MTT assay, IC50 = 5.16 μM. 19836231
HeLa Cytotoxicity assay Cytotoxicity against human HeLa cells by MTT assay, IC50 = 2.15 μM. 19836231
HL60 Cytotoxicity assay Cytotoxicity against human HL60 cells by MTT assay, IC50 = 0.93 μM. 19836231
HT-29 Cytotoxicity assay Cytotoxicity against human HT-29 cells by MTT assay, IC50 = 6.32 μM. 19836231
MDA-MB-231 Cytotoxicity assay Cytotoxicity against human MDA-MB-231 cells by MTT assay, IC50 = 3.5 μM. 19836231
KB Cytotoxicity assay Cytotoxicity against human KB cells, EC50 = 1.1 μM. 20102168
DU145 Cytotoxicity assay Cytotoxicity against human DU145 cells in presence of 10% fetal bovine serum, IC50 = 2.45 μM. 20188578
HCT15 Cytotoxicity assay Cytotoxicity against human HCT15 cells in presence of 10% fetal bovine serum, IC50 = 1.29 μM. 20188578
HeLa Cytotoxicity assay Cytotoxicity against human HeLa cells in presence of 10% fetal bovine serum, IC50 = 1.57 μM. 20188578
K562 Cytotoxicity assay Cytotoxicity against human K562 cells in presence of 10% fetal bovine serum, IC50 = 2.84 μM. 20188578
HeLa Cytotoxicity assay Cytotoxicity against human HeLa cells by MTT assay, IC50 = 8.93 μM. 20356735
HL60 Cytotoxicity assay Cytotoxicity against human HL60 cells by MTT assay, IC50 = 1.81 μM. 20356735
HL60 Cytotoxicity assay Cytotoxicity against human HL60 cells, IC50 = 0.49 μM. 20863598
NCI60 Growth inhibition assay Growth inhibition of human NCI60 cells by SBR assay, GI50 = 38.9045 μM. 21035334
DU145 Cytotoxicity assay Cytotoxicity against human DU145 cells by MTT assay, IC50 = 1.44 μM. 21115246
HCT15 Cytotoxicity assay Cytotoxicity against human HCT15 cells by MTT assay, IC50 = 2.03 μM. 21115246
K562 Cytotoxicity assay Cytotoxicity against human K562 cells by MTT assay, IC50 = 1.21 μM. 21115246
MCF7 Cytotoxicity assay Cytotoxicity against human MCF7 cells by MTT assay, IC50 = 1.98 μM. 21115246
HepG2 Cytotoxicity assay Cytotoxicity against human HepG2 cells by MTT assay, IC50 = 15.8 μM. 21174408
MOLT3 Cytotoxicity assay Cytotoxicity against human MOLT3 cells by XTT assay, IC50 = 0.03 μM. 21174408
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by SRB assay, IC50 = 1.85 μM. 21182258
SK-MEL-2 Cytotoxicity assay Cytotoxicity against human SK-MEL-2 cells by SRB assay, IC50 = 1.17 μM. 21182258
SKOV3 Cytotoxicity assay Cytotoxicity against human SKOV3 cells by SRB assay, IC50 = 1.81 μM. 21182258
XF498 Cytotoxicity assay Cytotoxicity against human XF498 cells by SRB assay, IC50 = 1.72 μM. 21182258
A549 Anticancer assay Anticancer activity against human A549 cells by SRB assay, IC50 = 1.85 μM. 21420296
SK-MEL-2 Anticancer assay Anticancer activity against human SK-MEL-2 cells by SRB assay, IC50 = 1.17 μM. 21420296
SKOV3 Anticancer assay Anticancer activity against human SKOV3 cells by SRB assay, IC50 = 1.81 μM. 21420296
XF498 Anticancer assay Anticancer activity against human XF498 cells by SRB assay, IC50 = 1.72 μM. 21420296
HL60 Cytotoxicity assay Cytotoxicity against human HL60 cells, IC50 = 1.4 μM. 21439821
HL60/MX2 Cytotoxicity assay Cytotoxicity against human HL60/MX2 cells, IC50 = 15.75 μM. 21439821
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by sulforhodamine B assay, IC50 = 0.44 μM. 21936523
SK-MEL-2 Cytotoxicity assay Cytotoxicity against human SK-MEL-2 cells by sulforhodamine B assay, IC50 = 0.41 μM. 21936523
SKOV3 Cytotoxicity assay Cytotoxicity against human SKOV3 cells by sulforhodamine B assay, IC50 = 1.31 μM. 21936523
HBL100 Growth inhibition assay Growth inhibition of human HBL100 cells, GI50 = 2.3 μM. 21986585
HeLa Growth inhibition assay Growth inhibition of human HeLa cells, GI50 = 3 μM. 21986585
Ishikawa Growth inhibition assay Growth inhibition of human Ishikawa cells, GI50 = 11 μM. 21986585
SW1573 Growth inhibition assay Growth inhibition of human SW1573 cells, GI50 = 15 μM. 21986585
T47D Growth inhibition assay Growth inhibition of human T47D cells, GI50 = 22 μM. 21986585
WiDr Growth inhibition assay Growth inhibition of human WiDr cells, GI50 = 23 μM. 21986585
Bel7402 Cytotoxicity assay Cytotoxicity against human Bel7402 cells, IC50 = 0.08 μM. 23092389
HeLa Cytotoxicity assay Cytotoxicity against human HeLa cells, IC50 = 0.08 μM. 23092389
SGC7901 Cytotoxicity assay Cytotoxicity against human SGC7901 cells, IC50 = 0.08 μM. 23092389
P388 Cytotoxicity assay Cytotoxicity against mouse P388 cells, IC50 = 0.08 μM. 23092389
SNU638 Cytotoxicity assay Cytotoxicity against human SNU638 cells by MTT assay, IC50 = 2.57 μM. 23608763
T47D Cytotoxicity assay Cytotoxicity against human T47D cells by MTT assay, IC50 = 4.98 μM. 23608763
H460 Cytotoxicity assay Cytotoxicity against human H460 cells assessed as growth inhibition by MTT assay, IC50 = 30 μM. 23920485
MCF7 Cytotoxicity assay Cytotoxicity against human MCF7 cells assessed as growth inhibition by MTT assay, IC50 = 20.9 μM. 23920485
PC3 Cytotoxicity assay Cytotoxicity against human PC3 cells assessed as growth inhibition by MTT assay, IC50 = 18.2 μM. 23920485
HeLa Cytotoxicity assay Cytotoxicity against human HeLa cells by MTT assay, IC50 = 0.0057 μM. 24422592
BGC823 Cytotoxicity assay Cytotoxicity against human BGC823 cells, IC50 = 25.72 μM. 24775914
HepG2 Cytotoxicity assay Cytotoxicity against human HepG2 cells, IC50 = 1.15 μM. 24775914
KB Antiproliferative assay Antiproliferative activity against human KB cells, IC50 = 1.1 μM. 25059503
KB-S15 Antiproliferative assay Antiproliferative activity against human KB-S15 cells, IC50 = 3.5 μM. 25059503
KB-VIN10 Antiproliferative assay Antiproliferative activity against human KB-VIN10 cells, IC50 = 23 μM. 25059503
SKMES1 Cytotoxicity assay Cytotoxicity against human SKMES1 cells, IC50 = 1.83 μM. 25440884
HepG2 Cytotoxicity assay Cytotoxicity against human HepG2 cells by MTT assay, IC50 = 40.47 μM. 25747499
MOLT3 Cytotoxicity assay Cytotoxicity against human MOLT3 cells by XTT assay, IC50 = 0.11 μM. 25747499
MCF7 Cytotoxicity assay Cytotoxicity against human MCF7 cells by MTT assay, IC50 = 7.6 μM. 25847767
MDA-MB-231 Cytotoxicity assay Cytotoxicity against human MDA-MB-231 cells by MTT assay, IC50 = 10.3 μM. 25847767
T47D Cytotoxicity assay Cytotoxicity against human T47D cells by MTT assay, IC50 = 8.9 μM. 25847767
A549 Antiproliferative assay Antiproliferative activity against human A549 cells by MTT assay, IC50 = 18.2 μM. 26216018
HepG2 Antiproliferative assay Antiproliferative activity against human HepG2 cells by MTT assay, IC50 = 20.9 μM. 26216018
A549 Cytotoxicity assay Cytotoxicity in human A549 cells by SRB assay, IC50 = 1.4 μM. 26812172
HCT116 Cytotoxicity assay Cytotoxicity in human HCT116 cells by SRB assay, IC50 = 1 μM. 26812172
SK-MEL-2 Cytotoxicity assay Cytotoxicity in human SK-MEL-2 cells by SRB assay, IC50 = 1.5 μM. 26812172
SKOV3 Cytotoxicity assay Cytotoxicity in human SKOV3 cells by SRB assay, IC50 = 2.6 μM. 26812172
A549 Cytotoxicity assay Cytotoxicity against human A549 cells by SRB assay, IC50 = 1.85 μM. 26988298
SK-MEL-2 Cytotoxicity assay Cytotoxicity against human SK-MEL-2 cells by SRB assay, IC50 = 1.17 μM. 26988298
SKOV3 Cytotoxicity assay Cytotoxicity against human SKOV3 cells by SRB assay, IC50 = 0.84 μM. 26988298
XF498 Cytotoxicity assay Cytotoxicity against human XF498 cells by SRB assay, IC50 = 1.72 μM. 26988298
HL60 Cytotoxicity assay Cytotoxicity against human HL60 cells assessed as reduction in cell survival, IC50 = 0.025 μM. 27234147
HepG2 Cytotoxicity assay Cytotoxicity against human HepG2 cells by MTT assay, IC50 = 15.8 μM. 27759375
HCT116 Cytotoxicity assay Cytotoxicity against human HCT116 cells assessed as growth inhibition by MTS assay, IC50 = 0.49 μM. 28055208
A549 Cytotoxicity assay Cytotoxicity against human A549 cells assessed as reduction in cell viability by MTT assay, IC50 = 16.6 μM. 28571311
HeLa Cytotoxicity assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability by MTT assay, IC50 = 15 μM. 28571311
HepG2 Cytotoxicity assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay, IC50 = 16.1 μM. 28571311
MCF7 Cytotoxicity assay Cytotoxicity against human MCF7 cells by MTT assay, IC50 = 12.4 μM. 28886509
HeLaS3 Antiproliferative assay Antiproliferative activity against human HeLaS3 cells by MTT assay, IC50 = 0.5 μM. 29072457
HT-29 Antiproliferative assay Antiproliferative activity against human HT-29 cells by MTT assay, IC50 = 7.6 μM. 29072457
K562 Antiproliferative assay Antiproliferative activity against human K562 cells, IC50 = 0.3 μM. 29871847
K/VP.5 Function assay Inhibition of human topoisomerase-2 in etoposide-resistant K/VP.5 cells assessed as growth inhibition, IC50 = 5.1 μM. 29871847
RH-1 Growth inhibition assay IC50 = 0.01778 μM SANGER
A253 Growth inhibition assay IC50 = 0.01843 μM SANGER
HT-144 Growth inhibition assay IC50 = 0.02009 μM SANGER
EW-16 Growth inhibition assay IC50 = 0.02148 μM SANGER
NTERA-S-cl-D1 Growth inhibition assay IC50 = 0.02502 μM SANGER
KE-37 Growth inhibition assay IC50 = 0.04072 μM SANGER
SK-UT-1 Growth inhibition assay IC50 = 0.04237 μM SANGER
OCUB-M Growth inhibition assay IC50 = 0.04455 μM SANGER
8-MG-BA Growth inhibition assay IC50 = 0.04687 μM SANGER
TE-9 Growth inhibition assay IC50 = 0.05593 μM SANGER
CGTH-W-1 Growth inhibition assay IC50 = 0.05741 μM SANGER
BB30-HNC Growth inhibition assay IC50 = 0.06418 μM SANGER
ACN Growth inhibition assay IC50 = 0.07896 μM SANGER
EW-13 Growth inhibition assay IC50 = 0.08885 μM SANGER
DU-4475 Growth inhibition assay IC50 = 0.09615 μM SANGER
HGC-27 Growth inhibition assay IC50 = 0.10212 μM SANGER
A427 Growth inhibition assay IC50 = 0.10338 μM SANGER
HT-1080 Growth inhibition assay IC50 = 0.10853 μM SANGER
MC-IXC Growth inhibition assay IC50 = 0.11512 μM SANGER
MRK-nu-1 Growth inhibition assay IC50 = 0.1162 μM SANGER
EW-7 Growth inhibition assay IC50 = 0.12506 μM SANGER
SW982 Growth inhibition assay IC50 = 0.13069 μM SANGER
SIG-M5 Growth inhibition assay IC50 = 0.13082 μM SANGER
PA-1 Growth inhibition assay IC50 = 0.13219 μM SANGER
ES8 Growth inhibition assay IC50 = 0.14221 μM SANGER
MV-4-11 Growth inhibition assay IC50 = 0.15121 μM SANGER
QIMR-WIL Growth inhibition assay IC50 = 0.15458 μM SANGER
COLO-679 Growth inhibition assay IC50 = 0.16303 μM SANGER
CCRF-CEM Growth inhibition assay IC50 = 0.17043 μM SANGER
IGROV-1 Growth inhibition assay IC50 = 0.17072 μM SANGER
LOUCY Growth inhibition assay IC50 = 0.1766 μM SANGER
ML-2 Growth inhibition assay IC50 = 0.17847 μM SANGER
RS4-11 Growth inhibition assay IC50 = 0.19612 μM SANGER
DJM-1 Growth inhibition assay IC50 = 0.20294 μM SANGER
ATN-1 Growth inhibition assay IC50 = 0.20386 μM SANGER
NALM-6 Growth inhibition assay IC50 = 0.20584 μM SANGER
HUTU-80 Growth inhibition assay IC50 = 0.21676 μM SANGER
REH Growth inhibition assay IC50 = 0.22424 μM SANGER
NCI-H2030 Growth inhibition assay IC50 = 0.22992 μM SANGER
A204 Growth inhibition assay IC50 = 0.23248 μM SANGER
NCI-H460 Growth inhibition assay IC50 = 0.23571 μM SANGER
697 Growth inhibition assay IC50 = 0.2432 μM SANGER
KYSE-270 Growth inhibition assay IC50 = 0.25188 μM SANGER
ES1 Growth inhibition assay IC50 = 0.25434 μM SANGER
COLO-205 Growth inhibition assay IC50 = 0.26497 μM SANGER
SK-HEP-1 Growth inhibition assay IC50 = 0.26712 μM SANGER
RPMI-8402 Growth inhibition assay IC50 = 0.27109 μM SANGER
H4 Growth inhibition assay IC50 = 0.29654 μM SANGER
LU-134-A Growth inhibition assay IC50 = 0.29919 μM SANGER
EoL-1-cell Growth inhibition assay IC50 = 0.30172 μM SANGER
SBC-5 Growth inhibition assay IC50 = 0.30262 μM SANGER
DEL Growth inhibition assay IC50 = 0.31149 μM SANGER
P12-ICHIKAWA Growth inhibition assay IC50 = 0.31679 μM SANGER
AGS Growth inhibition assay IC50 = 0.31823 μM SANGER
KS-1 Growth inhibition assay IC50 = 0.33444 μM SANGER
SK-PN-DW Growth inhibition assay IC50 = 0.34228 μM SANGER
DOHH-2 Growth inhibition assay IC50 = 0.34733 μM SANGER
KGN Growth inhibition assay IC50 = 0.35189 μM SANGER
A3-KAW Growth inhibition assay IC50 = 0.35826 μM SANGER
M059J Growth inhibition assay IC50 = 0.36401 μM SANGER
Daoy Growth inhibition assay IC50 = 0.36773 μM SANGER
MKN1 Growth inhibition assay IC50 = 0.38169 μM SANGER
CESS Growth inhibition assay IC50 = 0.38386 μM SANGER
SW620 Growth inhibition assay IC50 = 0.38448 μM SANGER
NCI-H1355 Growth inhibition assay IC50 = 0.38972 μM SANGER
EB2 Growth inhibition assay IC50 = 0.39146 μM SANGER
ABC-1 Growth inhibition assay IC50 = 0.40453 μM SANGER
GT3TKB Growth inhibition assay IC50 = 0.40644 μM SANGER
CTV-1 Growth inhibition assay IC50 = 0.40969 μM SANGER
VA-ES-BJ Growth inhibition assay IC50 = 0.41481 μM SANGER
KP-4 Growth inhibition assay IC50 = 0.41615 μM SANGER
MOLT-4 Growth inhibition assay IC50 = 0.41754 μM SANGER
NKM-1 Growth inhibition assay IC50 = 0.42516 μM SANGER
A2058 Growth inhibition assay IC50 = 0.42537 μM SANGER
BFTC-905 Growth inhibition assay IC50 = 0.42621 μM SANGER
SR Growth inhibition assay IC50 = 0.44265 μM SANGER
NCI-H526 Growth inhibition assay IC50 = 0.45612 μM SANGER
MES-SA Growth inhibition assay IC50 = 0.45821 μM SANGER
MHH-ES-1 Growth inhibition assay IC50 = 0.46271 μM SANGER
IMR-5 Growth inhibition assay IC50 = 0.46935 μM SANGER
RKO Growth inhibition assay IC50 = 0.47075 μM SANGER
HOS Growth inhibition assay IC50 = 0.47376 μM SANGER
647-V Growth inhibition assay IC50 = 0.48734 μM SANGER
786-0 Growth inhibition assay IC50 = 0.4922 μM SANGER
Calu-3 Growth inhibition assay IC50 = 0.49556 μM SANGER
U251 Growth inhibition assay IC50 = 0.50083 μM SANGER
23132-87 Growth inhibition assay IC50 = 0.50139 μM SANGER
BE-13 Growth inhibition assay IC50 = 0.50368 μM SANGER
SW1710 Growth inhibition assay IC50 = 0.51838 μM SANGER
ES4 Growth inhibition assay IC50 = 0.52145 μM SANGER
HOP-62 Growth inhibition assay IC50 = 0.52437 μM SANGER
MHH-NB-11 Growth inhibition assay IC50 = 0.52443 μM SANGER
KYSE-150 Growth inhibition assay IC50 = 0.53039 μM SANGER
ESS-1 Growth inhibition assay IC50 = 0.53078 μM SANGER
HLE Growth inhibition assay IC50 = 0.53357 μM SANGER
NEC8 Growth inhibition assay IC50 = 0.53895 μM SANGER
HC-1 Growth inhibition assay IC50 = 0.54032 μM SANGER
BC-1 Growth inhibition assay IC50 = 0.54533 μM SANGER
SK-LMS-1 Growth inhibition assay IC50 = 0.5528 μM SANGER
NCI-H2342 Growth inhibition assay IC50 = 0.55508 μM SANGER
OCI-AML2 Growth inhibition assay IC50 = 0.55935 μM SANGER
KYSE-510 Growth inhibition assay IC50 = 0.56639 μM SANGER
HMV-II Growth inhibition assay IC50 = 0.56879 μM SANGER
RPMI-2650 Growth inhibition assay IC50 = 0.57196 μM SANGER
DMS-273 Growth inhibition assay IC50 = 0.57348 μM SANGER
MC-CAR Growth inhibition assay IC50 = 0.57962 μM SANGER
DU-145 Growth inhibition assay IC50 = 0.59125 μM SANGER
HCC1599 Growth inhibition assay IC50 = 0.61627 μM SANGER
RT-112 Growth inhibition assay IC50 = 0.62053 μM SANGER
CAL-148 Growth inhibition assay IC50 = 0.62544 μM SANGER
ES3 Growth inhibition assay IC50 = 0.62849 μM SANGER
A375 Growth inhibition assay IC50 = 0.63084 μM SANGER
SW872 Growth inhibition assay IC50 = 0.6404 μM SANGER
LCLC-103H Growth inhibition assay IC50 = 0.6511 μM SANGER
MEL-JUSO Growth inhibition assay IC50 = 0.6571 μM SANGER
NH-12 Growth inhibition assay IC50 = 0.67198 μM SANGER
NCI-H187 Growth inhibition assay IC50 = 0.67362 μM SANGER
CAL-33 Growth inhibition assay IC50 = 0.6858 μM SANGER
ALL-PO Growth inhibition assay IC50 = 0.68979 μM SANGER
8505C Growth inhibition assay IC50 = 0.69275 μM SANGER
NCI-H2009 Growth inhibition assay IC50 = 0.69655 μM SANGER
KURAMOCHI Growth inhibition assay IC50 = 0.6986 μM SANGER
HSC-2 Growth inhibition assay IC50 = 0.70578 μM SANGER
SUP-T1 Growth inhibition assay IC50 = 0.70586 μM SANGER
GI-1 Growth inhibition assay IC50 = 0.71317 μM SANGER
TUR Growth inhibition assay IC50 = 0.72224 μM SANGER
PF-382 Growth inhibition assay IC50 = 0.72388 μM SANGER
MEL-HO Growth inhibition assay IC50 = 0.72874 μM SANGER
BCPAP Growth inhibition assay IC50 = 0.73695 μM SANGER
MFH-ino Growth inhibition assay IC50 = 0.7513 μM SANGER
ONS-76 Growth inhibition assay IC50 = 0.75429 μM SANGER
MFE-296 Growth inhibition assay IC50 = 0.76297 μM SANGER
NCI-H2087 Growth inhibition assay IC50 = 0.76306 μM SANGER
LCLC-97TM1 Growth inhibition assay IC50 = 0.76624 μM SANGER
ES7 Growth inhibition assay IC50 = 0.76713 μM SANGER
A431 Growth inhibition assay IC50 = 0.79754 μM SANGER
HCE-4 Growth inhibition assay IC50 = 0.80135 μM SANGER
SK-MES-1 Growth inhibition assay IC50 = 0.80842 μM SANGER
MZ1-PC Growth inhibition assay IC50 = 0.8111 μM SANGER
ME-180 Growth inhibition assay IC50 = 0.8238 μM SANGER
MCF7 Growth inhibition assay IC50 = 0.8305 μM SANGER
G-361 Growth inhibition assay IC50 = 0.83387 μM SANGER
ACHN Growth inhibition assay IC50 = 0.83874 μM SANGER
A4-Fuk Growth inhibition assay IC50 = 0.84103 μM SANGER
SCC-9 Growth inhibition assay IC50 = 0.84957 μM SANGER
IST-SL2 Growth inhibition assay IC50 = 0.85003 μM SANGER
CAL-62 Growth inhibition assay IC50 = 0.85117 μM SANGER
C-33-A Growth inhibition assay IC50 = 0.86169 μM SANGER
5637 Growth inhibition assay IC50 = 0.86693 μM SANGER
EFM-19 Growth inhibition assay IC50 = 0.86752 μM SANGER
SW48 Growth inhibition assay IC50 = 0.86895 μM SANGER
NCI-H748 Growth inhibition assay IC50 = 0.87069 μM SANGER
CHL-1 Growth inhibition assay IC50 = 0.8829 μM SANGER
G-402 Growth inhibition assay IC50 = 0.89819 μM SANGER
LS-411N Growth inhibition assay IC50 = 0.92538 μM SANGER
GCIY Growth inhibition assay IC50 = 0.92549 μM SANGER
HuO9 Growth inhibition assay IC50 = 0.92578 μM SANGER
BPH-1 Growth inhibition assay IC50 = 0.94282 μM SANGER
ECC12 Growth inhibition assay IC50 = 0.95438 μM SANGER
SU-DHL-1 Growth inhibition assay IC50 = 0.95915 μM SANGER
TE-15 Growth inhibition assay IC50 = 0.95964 μM SANGER
BB65-RCC Growth inhibition assay IC50 = 0.97887 μM SANGER
NUGC-3 Growth inhibition assay IC50 = 0.98081 μM SANGER
HCT-116 Growth inhibition assay IC50 = 1.00749 μM SANGER
639-V Growth inhibition assay IC50 = 1.00797 μM SANGER
RPMI-6666 Growth inhibition assay IC50 = 1.03221 μM SANGER
DoTc2-4510 Growth inhibition assay IC50 = 1.04831 μM SANGER
L-540 Growth inhibition assay IC50 = 1.05791 μM SANGER
NB12 Growth inhibition assay IC50 = 1.08357 μM SANGER
CAL-51 Growth inhibition assay IC50 = 1.08397 μM SANGER
NB69 Growth inhibition assay IC50 = 1.0875 μM SANGER
OVCAR-8 Growth inhibition assay IC50 = 1.09145 μM SANGER
A2780 Growth inhibition assay IC50 = 1.10527 μM SANGER
RL95-2 Growth inhibition assay IC50 = 1.11034 μM SANGER
HT-3 Growth inhibition assay IC50 = 1.12847 μM SANGER
UM-UC-3 Growth inhibition assay IC50 = 1.14554 μM SANGER
BFTC-909 Growth inhibition assay IC50 = 1.16148 μM SANGER
SNG-M Growth inhibition assay IC50 = 1.16368 μM SANGER
MG-63 Growth inhibition assay IC50 = 1.17999 μM SANGER
TE-5 Growth inhibition assay IC50 = 1.18327 μM SANGER
A101D Growth inhibition assay IC50 = 1.19812 μM SANGER
NCI-H209 Growth inhibition assay IC50 = 1.20699 μM SANGER
SCC-3 Growth inhibition assay IC50 = 1.21017 μM SANGER
P30-OHK Growth inhibition assay IC50 = 1.21124 μM SANGER
YKG-1 Growth inhibition assay IC50 = 1.22754 μM SANGER
CAPAN-1 Growth inhibition assay IC50 = 1.24645 μM SANGER
HCC2998 Growth inhibition assay IC50 = 1.25705 μM SANGER
HSC-4 Growth inhibition assay IC50 = 1.26252 μM SANGER
SAS Growth inhibition assay IC50 = 1.2672 μM SANGER
COR-L279 Growth inhibition assay IC50 = 1.26744 μM SANGER
FADU Growth inhibition assay IC50 = 1.28154 μM SANGER
SK-LU-1 Growth inhibition assay IC50 = 1.28962 μM SANGER
NCI-H1703 Growth inhibition assay IC50 = 1.29939 μM SANGER
KASUMI-1 Growth inhibition assay IC50 = 1.32239 μM SANGER
NCI-H1694 Growth inhibition assay IC50 = 1.37183 μM SANGER
LK-2 Growth inhibition assay IC50 = 1.40757 μM SANGER
CHP-212 Growth inhibition assay IC50 = 1.41096 μM SANGER
HSC-3 Growth inhibition assay IC50 = 1.43589 μM SANGER
G-401 Growth inhibition assay IC50 = 1.43693 μM SANGER
SF126 Growth inhibition assay IC50 = 1.44086 μM SANGER
HuP-T4 Growth inhibition assay IC50 = 1.45259 μM SANGER
EW-1 Growth inhibition assay IC50 = 1.45847 μM SANGER
MDA-MB-468 Growth inhibition assay IC50 = 1.46554 μM SANGER
NCI-H1734 Growth inhibition assay IC50 = 1.50503 μM SANGER
22RV1 Growth inhibition assay IC50 = 1.53054 μM SANGER
BHY Growth inhibition assay IC50 = 1.53169 μM SANGER
OVCAR-5 Growth inhibition assay IC50 = 1.53748 μM SANGER
EM-2 Growth inhibition assay IC50 = 1.57782 μM SANGER
NCI-H810 Growth inhibition assay IC50 = 1.58283 μM SANGER
IGR-1 Growth inhibition assay IC50 = 1.59112 μM SANGER
J-RT3-T3-5 Growth inhibition assay IC50 = 1.59438 μM SANGER
SF539 Growth inhibition assay IC50 = 1.60689 μM SANGER
GB-1 Growth inhibition assay IC50 = 1.60936 μM SANGER
SK-CO-1 Growth inhibition assay IC50 = 1.62804 μM SANGER
BOKU Growth inhibition assay IC50 = 1.63222 μM SANGER
PANC-03-27 Growth inhibition assay IC50 = 1.6369 μM SANGER
SF295 Growth inhibition assay IC50 = 1.65606 μM SANGER
COLO-668 Growth inhibition assay IC50 = 1.66431 μM SANGER
KM-H2 Growth inhibition assay IC50 = 1.66942 μM SANGER
C8166 Growth inhibition assay IC50 = 1.6773 μM SANGER
CTB-1 Growth inhibition assay IC50 = 1.68766 μM SANGER
NCI-H650 Growth inhibition assay IC50 = 1.70971 μM SANGER
C-4-II Growth inhibition assay IC50 = 1.71356 μM SANGER
NCI-H1650 Growth inhibition assay IC50 = 1.73565 μM SANGER
NCI-SNU-1 Growth inhibition assay IC50 = 1.75327 μM SANGER
SNU-423 Growth inhibition assay IC50 = 1.75342 μM SANGER
COLO-829 Growth inhibition assay IC50 = 1.76857 μM SANGER
SW13 Growth inhibition assay IC50 = 1.80203 μM SANGER
NCI-H2170 Growth inhibition assay IC50 = 1.85285 μM SANGER
MKN45 Growth inhibition assay IC50 = 1.87359 μM SANGER
KM12 Growth inhibition assay IC50 = 1.87938 μM SANGER
SN12C Growth inhibition assay IC50 = 1.88379 μM SANGER
SK-NEP-1 Growth inhibition assay IC50 = 1.90148 μM SANGER
HuCCT1 Growth inhibition assay IC50 = 1.91064 μM SANGER
SW954 Growth inhibition assay IC50 = 1.96311 μM SANGER
VMRC-RCZ Growth inhibition assay IC50 = 1.96786 μM SANGER
HT-29 Growth inhibition assay IC50 = 1.97537 μM SANGER
LB647-SCLC Growth inhibition assay IC50 = 2.00119 μM SANGER
KU812 Growth inhibition assay IC50 = 2.03197 μM SANGER
LoVo Growth inhibition assay IC50 = 2.06081 μM SANGER
LC-2-ad Growth inhibition assay IC50 = 2.06407 μM SANGER
KYSE-180 Growth inhibition assay IC50 = 2.06953 μM SANGER
NCI-H1299 Growth inhibition assay IC50 = 2.0703 μM SANGER
LXF-289 Growth inhibition assay IC50 = 2.07522 μM SANGER
BL-41 Growth inhibition assay IC50 = 2.08098 μM SANGER
COLO-800 Growth inhibition assay IC50 = 2.09855 μM SANGER
LB1047-RCC Growth inhibition assay IC50 = 2.13516 μM SANGER
OAW-28 Growth inhibition assay IC50 = 2.15234 μM SANGER
CAL-85-1 Growth inhibition assay IC50 = 2.15944 μM SANGER
A673 Growth inhibition assay IC50 = 2.16359 μM SANGER
MZ2-MEL Growth inhibition assay IC50 = 2.17939 μM SANGER
NOMO-1 Growth inhibition assay IC50 = 2.18798 μM SANGER
Ca9-22 Growth inhibition assay IC50 = 2.18807 μM SANGER
ARH-77 Growth inhibition assay IC50 = 2.18911 μM SANGER
D-283MED Growth inhibition assay IC50 = 2.19537 μM SANGER
AN3-CA Growth inhibition assay IC50 = 2.20226 μM SANGER
ST486 Growth inhibition assay IC50 = 2.24988 μM SANGER
SW1573 Growth inhibition assay IC50 = 2.25339 μM SANGER
769-P Growth inhibition assay IC50 = 2.25653 μM SANGER
HCC38 Growth inhibition assay IC50 = 2.27106 μM SANGER
RPMI-7951 Growth inhibition assay IC50 = 2.28584 μM SANGER
HL-60 Growth inhibition assay IC50 = 2.29181 μM SANGER
NCI-H1304 Growth inhibition assay IC50 = 2.30406 μM SANGER
8305C Growth inhibition assay IC50 = 2.32067 μM SANGER
Ca-Ski Growth inhibition assay IC50 = 2.32829 μM SANGER
DSH1 Growth inhibition assay IC50 = 2.36138 μM SANGER
HEC-1 Growth inhibition assay IC50 = 2.3745 μM SANGER
HO-1-N-1 Growth inhibition assay IC50 = 2.37868 μM SANGER
TE-10 Growth inhibition assay IC50 = 2.38102 μM SANGER
TYK-nu Growth inhibition assay IC50 = 2.41237 μM SANGER
LU-99A Growth inhibition assay IC50 = 2.42772 μM SANGER
NCI-H2405 Growth inhibition assay IC50 = 2.43564 μM SANGER
BC-3 Growth inhibition assay IC50 = 2.47545 μM SANGER
RERF-LC-MS Growth inhibition assay IC50 = 2.49413 μM SANGER
JiyoyeP-2003 Growth inhibition assay IC50 = 2.5428 μM SANGER
MKN28 Growth inhibition assay IC50 = 2.54669 μM SANGER
SF268 Growth inhibition assay IC50 = 2.54745 μM SANGER
HuH-7 Growth inhibition assay IC50 = 2.56377 μM SANGER
VM-CUB-1 Growth inhibition assay IC50 = 2.57875 μM SANGER
AU565 Growth inhibition assay IC50 = 2.61126 μM SANGER
GAMG Growth inhibition assay IC50 = 2.61355 μM SANGER
DBTRG-05MG Growth inhibition assay IC50 = 2.62832 μM SANGER
NCI-H2228 Growth inhibition assay IC50 = 2.65509 μM SANGER
MIA-PaCa-2 Growth inhibition assay IC50 = 2.6613 μM SANGER
NCI-H1882 Growth inhibition assay IC50 = 2.67868 μM SANGER
CMK Growth inhibition assay IC50 = 2.68446 μM SANGER
ETK-1 Growth inhibition assay IC50 = 2.74528 μM SANGER
NB13 Growth inhibition assay IC50 = 2.76358 μM SANGER
PANC-10-05 Growth inhibition assay IC50 = 2.88779 μM SANGER
UACC-62 Growth inhibition assay IC50 = 2.91997 μM SANGER
SW756 Growth inhibition assay IC50 = 2.98046 μM SANGER
SJSA-1 Growth inhibition assay IC50 = 2.98416 μM SANGER
L-428 Growth inhibition assay IC50 = 2.98894 μM SANGER
IST-MEL1 Growth inhibition assay IC50 = 2.99943 μM SANGER
JEG-3 Growth inhibition assay IC50 = 3.04067 μM SANGER
SW1783 Growth inhibition assay IC50 = 3.05871 μM SANGER
BHT-101 Growth inhibition assay IC50 = 3.10736 μM SANGER
SH-4 Growth inhibition assay IC50 = 3.1346 μM SANGER
NCI-H358 Growth inhibition assay IC50 = 3.15154 μM SANGER
LC4-1 Growth inhibition assay IC50 = 3.22759 μM SANGER
GCT Growth inhibition assay IC50 = 3.26576 μM SANGER
EGI-1 Growth inhibition assay IC50 = 3.27013 μM SANGER
NMC-G1 Growth inhibition assay IC50 = 3.32432 μM SANGER
A388 Growth inhibition assay IC50 = 3.32957 μM SANGER
J82 Growth inhibition assay IC50 = 3.33987 μM SANGER
NCI-H522 Growth inhibition assay IC50 = 3.35766 μM SANGER
EFO-27 Growth inhibition assay IC50 = 3.35777 μM SANGER
NCI-H1437 Growth inhibition assay IC50 = 3.38115 μM SANGER
MLMA Growth inhibition assay IC50 = 3.38191 μM SANGER
GDM-1 Growth inhibition assay IC50 = 3.40206 μM SANGER
IA-LM Growth inhibition assay IC50 = 3.43569 μM SANGER
no-10 Growth inhibition assay IC50 = 3.48873 μM SANGER
NOS-1 Growth inhibition assay IC50 = 3.58057 μM SANGER
HCC1569 Growth inhibition assay IC50 = 3.58372 μM SANGER
FTC-133 Growth inhibition assay IC50 = 3.58908 μM SANGER
AM-38 Growth inhibition assay IC50 = 3.66706 μM SANGER
KYSE-450 Growth inhibition assay IC50 = 3.68871 μM SANGER
ChaGo-K-1 Growth inhibition assay IC50 = 3.79409 μM SANGER
HAL-01 Growth inhibition assay IC50 = 3.80443 μM SANGER
NCI-H1770 Growth inhibition assay IC50 = 3.86539 μM SANGER
HEL Growth inhibition assay IC50 = 3.89764 μM SANGER
NCI-H64 Growth inhibition assay IC50 = 3.99787 μM SANGER
LU-139 Growth inhibition assay IC50 = 4.00867 μM SANGER
LS-123 Growth inhibition assay IC50 = 4.02035 μM SANGER
Calu-6 Growth inhibition assay IC50 = 4.05854 μM SANGER
KP-N-YS Growth inhibition assay IC50 = 4.23582 μM SANGER
MZ7-mel Growth inhibition assay IC50 = 4.29859 μM SANGER
KARPAS-422 Growth inhibition assay IC50 = 4.3292 μM SANGER
IPC-298 Growth inhibition assay IC50 = 4.33485 μM SANGER
NCI-H661 Growth inhibition assay IC50 = 4.34179 μM SANGER
WSU-NHL Growth inhibition assay IC50 = 4.36044 μM SANGER
HH Growth inhibition assay IC50 = 4.44423 μM SANGER
NY Growth inhibition assay IC50 = 4.48988 μM SANGER
BT-20 Growth inhibition assay IC50 = 4.5794 μM SANGER
NCI-H1417 Growth inhibition assay IC50 = 4.60594 μM SANGER
CAL-39 Growth inhibition assay IC50 = 4.63617 μM SANGER
RPMI-8866 Growth inhibition assay IC50 = 4.64882 μM SANGER
NCI-H292 Growth inhibition assay IC50 = 4.7095 μM SANGER
SJRH30 Growth inhibition assay IC50 = 4.72366 μM SANGER
HCC1806 Growth inhibition assay IC50 = 4.73101 μM SANGER
MEG-01 Growth inhibition assay IC50 = 4.74917 μM SANGER
EW-11 Growth inhibition assay IC50 = 4.76565 μM SANGER
RD Growth inhibition assay IC50 = 4.80409 μM SANGER
KYSE-140 Growth inhibition assay IC50 = 4.91746 μM SANGER
NCI-H2081 Growth inhibition assay IC50 = 4.91765 μM SANGER
HOP-92 Growth inhibition assay IC50 = 5.02277 μM SANGER
BV-173 Growth inhibition assay IC50 = 5.05329 μM SANGER
OE33 Growth inhibition assay IC50 = 5.12216 μM SANGER
NCI-H1793 Growth inhibition assay IC50 = 5.30922 μM SANGER
Daudi Growth inhibition assay IC50 = 5.36115 μM SANGER
NCI-H2122 Growth inhibition assay IC50 = 5.39424 μM SANGER
SW1990 Growth inhibition assay IC50 = 5.639 μM SANGER
MS-1 Growth inhibition assay IC50 = 5.64297 μM SANGER
HT-1376 Growth inhibition assay IC50 = 5.81886 μM SANGER
GP5d Growth inhibition assay IC50 = 5.8311 μM SANGER
OAW-42 Growth inhibition assay IC50 = 6.05896 μM SANGER
LB831-BLC Growth inhibition assay IC50 = 6.15047 μM SANGER
COR-L23 Growth inhibition assay IC50 = 6.18279 μM SANGER
CP66-MEL Growth inhibition assay IC50 = 6.25378 μM SANGER
CHP-126 Growth inhibition assay IC50 = 6.27397 μM SANGER
GOTO Growth inhibition assay IC50 = 6.37509 μM SANGER
DB Growth inhibition assay IC50 = 6.5298 μM SANGER
L-363 Growth inhibition assay IC50 = 6.58998 μM SANGER
SCC-25 Growth inhibition assay IC50 = 6.63406 μM SANGER
CAKI-1 Growth inhibition assay IC50 = 6.65287 μM SANGER
GR-ST Growth inhibition assay IC50 = 6.68733 μM SANGER
Mewo Growth inhibition assay IC50 = 6.79226 μM SANGER
MMAC-SF Growth inhibition assay IC50 = 6.87553 μM SANGER
CCF-STTG1 Growth inhibition assay IC50 = 6.91149 μM SANGER
NCI-H1563 Growth inhibition assay IC50 = 7.06829 μM SANGER
BL-70 Growth inhibition assay IC50 = 7.07066 μM SANGER
SCC-4 Growth inhibition assay IC50 = 7.20234 μM SANGER
TE-11 Growth inhibition assay IC50 = 7.45503 μM SANGER
TK10 Growth inhibition assay IC50 = 7.49225 μM SANGER
NCI-H2196 Growth inhibition assay IC50 = 7.49486 μM SANGER
no-11 Growth inhibition assay IC50 = 7.55794 μM SANGER
HuO-3N1 Growth inhibition assay IC50 = 7.71346 μM SANGER
HCT-15 Growth inhibition assay IC50 = 7.87059 μM SANGER
Calu-1 Growth inhibition assay IC50 = 7.89022 μM SANGER
NCI-SNU-5 Growth inhibition assay IC50 = 7.91903 μM SANGER
C3A Growth inhibition assay IC50 = 7.93051 μM SANGER
M14 Growth inhibition assay IC50 = 7.94538 μM SANGER
KMOE-2 Growth inhibition assay IC50 = 8.03697 μM SANGER
NCI-H520 Growth inhibition assay IC50 = 8.03907 μM SANGER
NCI-H69 Growth inhibition assay IC50 = 8.18234 μM SANGER
SK-MEL-30 Growth inhibition assay IC50 = 8.24405 μM SANGER
COLO-680N Growth inhibition assay IC50 = 8.25621 μM SANGER
Raji Growth inhibition assay IC50 = 8.31941 μM SANGER
NCI-H2141 Growth inhibition assay IC50 = 8.52227 μM SANGER
HD-MY-Z Growth inhibition assay IC50 = 8.53777 μM SANGER
CaR-1 Growth inhibition assay IC50 = 8.60091 μM SANGER
A172 Growth inhibition assay IC50 = 8.64964 μM SANGER
NCI-H510A Growth inhibition assay IC50 = 8.65064 μM SANGER
TE-8 Growth inhibition assay IC50 = 8.75118 μM SANGER
T98G Growth inhibition assay IC50 = 8.81581 μM SANGER
SIMA Growth inhibition assay IC50 = 8.85231 μM SANGER
SW626 Growth inhibition assay IC50 = 8.90372 μM SANGER
CAL-54 Growth inhibition assay IC50 = 8.92125 μM SANGER
MDA-MB-231 Growth inhibition assay IC50 = 9.08645 μM SANGER
NCI-H630 Growth inhibition assay IC50 = 9.12079 μM SANGER
LAMA-84 Growth inhibition assay IC50 = 9.20893 μM SANGER
COR-L105 Growth inhibition assay IC50 = 9.56953 μM SANGER
NCI-H2347 Growth inhibition assay IC50 = 9.66391 μM SANGER
SK-MM-2 Growth inhibition assay IC50 = 9.68223 μM SANGER
PC-14 Growth inhibition assay IC50 = 9.72234 μM SANGER
KG-1 Growth inhibition assay IC50 = 9.72465 μM SANGER
COLO-320-HSR Growth inhibition assay IC50 = 9.73489 μM SANGER
GI-ME-N Growth inhibition assay IC50 = 9.82616 μM SANGER
KMS-12-PE Growth inhibition assay IC50 = 9.91106 μM SANGER
Ramos-2G6-4C10 Growth inhibition assay IC50 = 9.93808 μM SANGER
HCC1954 Growth inhibition assay IC50 = 10.0429 μM SANGER
SK-MEL-3 Growth inhibition assay IC50 = 10.1322 μM SANGER
NB1 Growth inhibition assay IC50 = 10.2077 μM SANGER
KLE Growth inhibition assay IC50 = 10.2925 μM SANGER
KALS-1 Growth inhibition assay IC50 = 10.3029 μM SANGER
NCI-H2126 Growth inhibition assay IC50 = 10.3993 μM SANGER
CAL-27 Growth inhibition assay IC50 = 10.4443 μM SANGER
SK-OV-3 Growth inhibition assay IC50 = 10.8274 μM SANGER
SNB75 Growth inhibition assay IC50 = 10.9411 μM SANGER
NCI-H1155 Growth inhibition assay IC50 = 11.02 μM SANGER
Detroit562 Growth inhibition assay IC50 = 11.0755 μM SANGER
CAL-12T Growth inhibition assay IC50 = 11.136 μM SANGER
NCI-H226 Growth inhibition assay IC50 = 11.1518 μM SANGER
NCI-H441 Growth inhibition assay IC50 = 11.166 μM SANGER
OS-RC-2 Growth inhibition assay IC50 = 11.2175 μM SANGER
U031 Growth inhibition assay IC50 = 11.2885 μM SANGER
NCI-H2052 Growth inhibition assay IC50 = 11.4502 μM SANGER
TCCSUP Growth inhibition assay IC50 = 11.6187 μM SANGER
T47D Growth inhibition assay IC50 = 11.6637 μM SANGER
Becker Growth inhibition assay IC50 = 11.8156 μM SANGER
EFO-21 Growth inhibition assay IC50 = 11.8503 μM SANGER
NCI-H1963 Growth inhibition assay IC50 = 12.0942 μM SANGER
MONO-MAC-6 Growth inhibition assay IC50 = 12.1309 μM SANGER
MOLT-16 Growth inhibition assay IC50 = 12.4619 μM SANGER
U-698-M Growth inhibition assay IC50 = 12.4627 μM SANGER
MDA-MB-157 Growth inhibition assay IC50 = 12.6094 μM SANGER
KYSE-410 Growth inhibition assay IC50 = 12.8456 μM SANGER
CAMA-1 Growth inhibition assay IC50 = 13.0046 μM SANGER
SCC-15 Growth inhibition assay IC50 = 13.1497 μM SANGER
NCI-H23 Growth inhibition assay IC50 = 13.1861 μM SANGER
KNS-42 Growth inhibition assay IC50 = 13.6511 μM SANGER
HDLM-2 Growth inhibition assay IC50 = 13.7938 μM SANGER
NCI-H1623 Growth inhibition assay IC50 = 13.9776 μM SANGER
RPMI-8226 Growth inhibition assay IC50 = 14.3243 μM SANGER
EW-3 Growth inhibition assay IC50 = 14.3337 μM SANGER
HT Growth inhibition assay IC50 = 15.2889 μM SANGER
CAL-120 Growth inhibition assay IC50 = 15.6326 μM SANGER
HCC1937 Growth inhibition assay IC50 = 15.7725 μM SANGER
NCI-N87 Growth inhibition assay IC50 = 15.8106 μM SANGER
NB10 Growth inhibition assay IC50 = 15.9987 μM SANGER
UACC-812 Growth inhibition assay IC50 = 16.4249 μM SANGER
MHH-PREB-1 Growth inhibition assay IC50 = 16.4817 μM SANGER
SNU-449 Growth inhibition assay IC50 = 16.6657 μM SANGER
COLO-684 Growth inhibition assay IC50 = 16.7953 μM SANGER
BxPC-3 Growth inhibition assay IC50 = 16.8611 μM SANGER
DMS-153 Growth inhibition assay IC50 = 16.9246 μM SANGER
SW962 Growth inhibition assay IC50 = 16.9729 μM SANGER
OVCAR-4 Growth inhibition assay IC50 = 17.3428 μM SANGER
CAS-1 Growth inhibition assay IC50 = 17.5833 μM SANGER
HPAF-II Growth inhibition assay IC50 = 17.6767 μM SANGER
NCI-H838 Growth inhibition assay IC50 = 17.9844 μM SANGER
D-247MG Growth inhibition assay IC50 = 18.052 μM SANGER
T-24 Growth inhibition assay IC50 = 18.0868 μM SANGER
YT Growth inhibition assay IC50 = 18.2712 μM SANGER
NCI-H596 Growth inhibition assay IC50 = 18.2999 μM SANGER
CPC-N Growth inhibition assay IC50 = 18.426 μM SANGER
HN Growth inhibition assay IC50 = 18.5533 μM SANGER
KARPAS-299 Growth inhibition assay IC50 = 19.2708 μM SANGER
ES6 Growth inhibition assay IC50 = 19.6334 μM SANGER
IST-SL1 Growth inhibition assay IC50 = 19.8912 μM SANGER
LOXIMVI Growth inhibition assay IC50 = 19.9253 μM SANGER
U-266 Growth inhibition assay IC50 = 19.9794 μM SANGER
HCC2157 Growth inhibition assay IC50 = 20.3328 μM SANGER
MPP-89 Growth inhibition assay IC50 = 20.7595 μM SANGER
MDA-MB-361 Growth inhibition assay IC50 = 20.8051 μM SANGER
RCM-1 Growth inhibition assay IC50 = 20.9952 μM SANGER
SW780 Growth inhibition assay IC50 = 21.109 μM SANGER
SK-MEL-2 Growth inhibition assay IC50 = 21.2698 μM SANGER
TE-1 Growth inhibition assay IC50 = 21.4838 μM SANGER
NB5 Growth inhibition assay IC50 = 21.8618 μM SANGER
OVCAR-3 Growth inhibition assay IC50 = 22.2138 μM SANGER
LNCaP-Clone-FGC Growth inhibition assay IC50 = 23.5156 μM SANGER
KYSE-520 Growth inhibition assay IC50 = 24.0956 μM SANGER
UMC-11 Growth inhibition assay IC50 = 24.3195 μM SANGER
NCCIT Growth inhibition assay IC50 = 24.4842 μM SANGER
OPM-2 Growth inhibition assay IC50 = 24.6118 μM SANGER
GAK Growth inhibition assay IC50 = 25.1015 μM SANGER
PLC-PRF-5 Growth inhibition assay IC50 = 25.4198 μM SANGER
K5 Growth inhibition assay IC50 = 25.5192 μM SANGER
HT55 Growth inhibition assay IC50 = 25.82 μM SANGER
HT-1197 Growth inhibition assay IC50 = 25.8682 μM SANGER
Saos-2 Growth inhibition assay IC50 = 26.0963 μM SANGER
NCI-H1648 Growth inhibition assay IC50 = 26.3623 μM SANGER
NCI-H747 Growth inhibition assay IC50 = 27.2478 μM SANGER
U-87-MG Growth inhibition assay IC50 = 27.5565 μM SANGER
LU-165 Growth inhibition assay IC50 = 28.8005 μM SANGER
Caov-3 Growth inhibition assay IC50 = 29.2228 μM SANGER
MN-60 Growth inhibition assay IC50 = 29.5512 μM SANGER
TE-6 Growth inhibition assay IC50 = 29.723 μM SANGER
EHEB Growth inhibition assay IC50 = 30.3605 μM SANGER
SNU-C2B Growth inhibition assay IC50 = 30.4898 μM SANGER
YAPC Growth inhibition assay IC50 = 30.5644 μM SANGER
LU-65 Growth inhibition assay IC50 = 30.8083 μM SANGER
HTC-C3 Growth inhibition assay IC50 = 30.8175 μM SANGER
HuP-T3 Growth inhibition assay IC50 = 30.9157 μM SANGER
LB2241-RCC Growth inhibition assay IC50 = 31.1032 μM SANGER
SK-N-DZ Growth inhibition assay IC50 = 31.4228 μM SANGER
KYSE-70 Growth inhibition assay IC50 = 32.3637 μM SANGER
EW-18 Growth inhibition assay IC50 = 32.7339 μM SANGER
NCI-H1651 Growth inhibition assay IC50 = 32.7543 μM SANGER
LS-1034 Growth inhibition assay IC50 = 33.1173 μM SANGER
RXF393 Growth inhibition assay IC50 = 33.7866 μM SANGER
OMC-1 Growth inhibition assay IC50 = 36.8562 μM SANGER
OE19 Growth inhibition assay IC50 = 36.9759 μM SANGER
MHH-CALL-2 Growth inhibition assay IC50 = 37.3808 μM SANGER
BB49-HNC Growth inhibition assay IC50 = 37.3849 μM SANGER
A498 Growth inhibition assay IC50 = 37.4282 μM SANGER
NCI-H1581 Growth inhibition assay IC50 = 37.647 μM SANGER
LB996-RCC Growth inhibition assay IC50 = 38.6567 μM SANGER
SKG-IIIa Growth inhibition assay IC50 = 38.976 μM SANGER
SBC-1 Growth inhibition assay IC50 = 39.1276 μM SANGER
TE-441-T Growth inhibition assay IC50 = 39.1447 μM SANGER
KINGS-1 Growth inhibition assay IC50 = 39.2733 μM SANGER
NCI-H28 Growth inhibition assay IC50 = 39.4002 μM SANGER
NCI-H1618 Growth inhibition assay IC50 = 40.1041 μM SANGER
MFE-280 Growth inhibition assay IC50 = 40.5005 μM SANGER
EB-3 Growth inhibition assay IC50 = 40.6243 μM SANGER
IM-9 Growth inhibition assay IC50 = 41.6341 μM SANGER
DV-90 Growth inhibition assay IC50 = 41.9741 μM SANGER
NCI-H1792 Growth inhibition assay IC50 = 42.6858 μM SANGER
SNU-387 Growth inhibition assay IC50 = 43.2181 μM SANGER
HCC1395 Growth inhibition assay IC50 = 44.7953 μM SANGER
TGW Growth inhibition assay IC50 = 46.3289 μM SANGER
KY821 Growth inhibition assay IC50 = 47.0932 μM SANGER
ECC4 Growth inhibition assay IC50 = 48.0182 μM SANGER
KARPAS-45 Growth inhibition assay IC50 = 48.2359 μM SANGER
LB2518-MEL Growth inhibition assay IC50 = 48.5056 μM SANGER
COR-L88 Growth inhibition assay IC50 = 48.735 μM SANGER
COLO-741 Growth inhibition assay IC50 = 48.8966 μM SANGER
HCE-T Growth inhibition assay IC50 = 49.301 μM SANGER
NCI-H1755 Growth inhibition assay IC50 = 49.3468 μM SANGER
点击查看更多细胞系数据

生物活性

产品描述 Etoposide是一种鬼臼毒素的半合成衍生物,通过抑制topoisomerase II 活性而抑制DNA合成,从而增强 DNA 的双链和单链裂解,并可逆地抑制topoisomerase II结合的修复。Etoposide可诱导自噬、线粒体自噬和细胞凋亡。
靶点
Topo II [2]
(Cell-free assay)
体外研究(In Vitro)
体外研究活性

Etoposide通过与Topoisomerase II 和 DNA形成复合物而抑制DNA合成,诱导双链DNA断裂,且阻碍通过 Topoisomerase II结合修复。DNA持续断裂阻碍进入细胞有丝分裂期,进而导致细胞死亡。Etoposide主要作用于细胞周期的G2期和S期。[1] Etoposide 抑制鼠类血管肉瘤细胞系 (ISOS-1) 生长,IC50 为0.25 μg/mL。Etoposide 抑制人类白血病成淋巴细胞系CCRF-CEM的四倍体克隆,IC50为0.6 μM。[3]

激酶实验 Topoisomerase II 活性测定
制备核提取物,进行核分离。在Topoisomerase II去连环过程中获得去连环百分数而计算Topoisomerase II的活性。氚标记的kinoplast DNA (KDNA 0.22 μg)作为底物。Etoposide 与 Topoisomerase II在37°C 下温育30分钟,然后加入1%十二烷基硫酸钠(SDS)和蛋白酶K(100 μg/mL)终止。通过Etoposide获得去连环百分数和 Topoisomerase II 抑制情况。
细胞实验 细胞系 人类胶质瘤细胞系CL5
浓度 80 μg/mL
孵育时间 1 小时
方法

Etoposide处理后,使用含有0.03%胰蛋白酶和0.27 mM乙二胺四乙酸(EDTA)的磷酸盐缓冲液(PBS)将细胞从培养皿中移去,然后在培养皿中稀释到适当数目,获得20到200个菌落。12天后,使用甲醇-乙酸固定培养基,使用结晶紫进行染色,并计数超过50个细胞的菌落。

实验图片 检测方法 检测指标 实验图片 PMID
Western blot p53 / p-p53 / Acetyl-p53 / TF-IIB p53 / p21 / c-Myc / PARP 23800173
Immunofluorescence YAP p53 pDNA-PKcs MDC1 γH2AX / pATM COX IV 27515249
Growth inhibition assay Cell viability 22615609
体内研究(In Vivo)
体内研究活性

Etoposide 作用于Lewis 肺癌,诱导肿瘤免疫。Etoposide按50 mg/kg剂量单独腹腔注射给药注射了Lewis肺癌细胞 (3LL)的C57B1/6小鼠,诱导60%存活。[4]

动物实验 Animal Models 携带血管肉瘤移植瘤ISOS-1 的小鼠
Dosages 10 mg/kg
Administration 从实验第7天开始,每天腹腔注射,持续5天
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06393816 Not yet recruiting
Large Cell Neuroendocrine Carcinoma of the Lung
Centre Leon Berard|Groupe Français de Pneumo-Cancérologie
May 2024 Phase 2
NCT06406465 Not yet recruiting
Carcinoma Neuroendocrine|Tumor Neuroendocrine|Tumors Neuroendocrine|Neuroendocrine; Carcinoma|Small Cell; Receptors
National Cancer Institute (NCI)|National Institutes of Health Clinical Center (CC)
May 15 2024 Phase 2
NCT06086288 Not yet recruiting
Merkel Cell Carcinoma
Fondazione IRCCS Istituto Nazionale dei Tumori Milano
November 2023 Phase 2

化学信息&溶解度

分子量 588.56 分子式

C29H32O13

CAS号 33419-42-0 SDF Download Etoposide SDF
Smiles CC1OCC2C(O1)C(C(C(O2)OC3C4COC(=O)C4C(C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O
储存条件(自收到货起)

体外溶解度
批次:

DMSO : 100 mg/mL ( (169.9 mM) ;DMSO吸湿会降低化合物溶解度,请使用新开封DMSO)

Water : Insoluble

Ethanol : Insoluble

摩尔浓度计算器

体内溶解度
批次:

现配现用,请按从左到右的顺序依次添加,澄清后再加入下一溶剂

动物体内配方计算器

实验计算

摩尔浓度计算器

质量 浓度 体积 分子量

动物体内配方计算器(澄清溶液)

第一步:请输入基本实验信息(考虑到实验过程中的损耗,建议多配一只动物的药量)

mg/kg g μL

第二步:请输入动物体内配方组成(配方适用于不溶于水的药物;不同批次药物配方比例不同,请联系Selleck为您提供正确的澄清溶液配方)

% DMSO % % Tween 80 % ddH2O
%DMSO %

计算结果:

工作液浓度: mg/ml;

DMSO母液配制方法: mg 药物溶于μL DMSO溶液(母液浓度mg/mL,:如该浓度超过该批次药物DMSO溶解度,请先联系Selleck);

体内配方配制方法:μL DMSO母液,加入μL PEG300,混匀澄清后加入μL Tween 80,混匀澄清后加入μL ddH2O,混匀澄清。

体内配方配制方法:μL DMSO母液,加入μL Corn oil,混匀澄清。

注意:1. 首先保证母液是澄清的;
2.一定要按照顺序依次将溶剂加入,进行下一步操作之前必须保证上一步操作得到的是澄清的溶液,可采用涡旋、超声或水浴加热等物理方法助溶。

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常见问题及建议解决方法

问题 1:
Regarding the Etoposide S1225, do you have any data of the inhibition sepcificity of this product? It will inhibit other enzymes other than TOP2A?

回答:
According to the available published data, the inhibition of Etoposide is specific to TOP2A. But there're also two papers showing that Etoposide could inhibit the p34cdc2 Kinase Activity: 1. http://cancerres.aacrjournals.org/content/52/7/1817.short ; 2. http://cancerres.aacrjournals.org/content/50/12/3761.short.

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