| S1509 |
Norfloxacin |
Norfloxacin (MK-0366) is a broad-spectrum antibiotic. Norfloxacin (MK-0366) targets bacterial gyrase and topoisomerase IV enzymes. |
Selective |
|
| S2027 |
Ciprofloxacin |
Ciprofloxacin (Bay o 9867,Bay q 3939) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity, with MIC90 of 0.024-6 μM. |
Selective |
|
| S1756 |
Enoxacin |
Enoxacin (AT-2266, CI919, Pd107779, NSC 629661) is an oral broad-spectrum fluoroquinolone antibacterial agent by inhibiting bacterial DNA gyrase and topoisomerase IV, used to treat a wide variety of infections. |
Pan |
|
| S1463 |
Ofloxacin |
Ofloxacin (DL8280) is a synthetic broad-spectrum antimicrobial agent. |
Pan |
|
| S2492 |
Novobiocin Sodium (NSC 2382) |
Novobiocin Sodium (NSC 2382, Albamycin, Cathomycin) is an aminocoumarin antibiotic that targets bacterial DNA gyrase (TopoIV), used to treat susceptible gram positive bacteria. |
Pan |
|
| S1340 |
Gatifloxacin |
Gatifloxacin (AM-1155, CG5501, BMS-206584) is an antibiotic of the fourth-generation fluoroquinolone family, and inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. |
Pan |
|
| S5964 |
Gatifloxacin hydrochloride |
Gatifloxacin (AM-1155, CG5501, BMS-206584, PD135432) hydrochloride is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases with IC50 of 13.8 μg/ml and 0.109 μg/ml for S. aureus topoisomerase IV and E. coli DNA gyrase, respectively. |
Pan |
|
| S1465 |
Moxifloxacin (BAY12-8039) HCl |
Moxifloxacin (Avelox, Avalox,BAY12-8039 HCl) is a fourth-generation synthetic fluoroquinolone antibacterial agent. |
Pan |
|
| S4006 |
Clinafloxacin |
Clinafloxacin (CI-960, PD127391, AM-1091) is a fluoroquinolone that inhibits both DNA gyrase and topoisomerase IV dually in Streptococcus pneumoniae. |
Pan |
|
| S2328 |
Nalidixic acid |
Nalidixic acid (NSC-82174) is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase. |
Pan |
|
| S1464 |
Marbofloxacin |
Marbofloxacin is a potent antibiotic inhibiting bacterial DNA replication. |
Pan |
|
| S1940 |
Levofloxacin |
Levofloxacin (Fluoroquinolone) is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections. |
Pan |
|
