| L1210 cell |
Cytotoxicity assay |
|
48 h |
Cytotoxic potency required to inhibit L1210 cell growth by 50% after cell drug contact for 48 hrs, IC50=4e-05 μM |
|
| HL60 cells |
Cytotoxicity assay |
|
48 h |
Cytotoxicity against human HL60 cells after 48 hrs by MTT assay, GI50=0.33 μM |
|
| human HL60 cells |
Proliferation assay |
|
72 h |
Antiproliferative activity against human HL60 cells after 72 hrs by SRB assay, IC50=2.5 nM |
|
| human K562 cells |
Cytotoxicity assay |
|
5 days |
Cytotoxicity against human K562 cells after 5 days by XTT assay, IC50=2.6 nM |
|
| MES-SA cells |
Proliferation assay |
|
72 h |
Antiproliferative activity against MES-SA cells by MTT assay after 72 hrs, IC50=3 nM |
|
| LoVo cells |
Cytotoxicity assay |
|
144 h |
Cytotoxicity against human LoVo cancer cell line was determined after 144 hr, IC50=3.3 nM |
|
| human Daudi cells |
Proliferation assay |
|
72 h |
Antiproliferative activity against human Daudi cells after 72 hrs by MTT assay, IC50=5 nM |
|
| human MES-SA cells |
Proliferation assay |
|
72 h |
Antiproliferative activity against human MES-SA cells after 72 hrs by MTT assay, IC50=6 nM |
|
| PC3 cancer cell |
Cytotoxicity assay |
|
144 h |
Cytotoxicity against human PC3 cancer cell line was determined after 144 hr, IC50=7 nM |
|
| HT-29 cell |
Cytotoxicity assay |
|
144 h |
Cytotoxic potency required to inhibit HT-29 cell growth by 50% after cell drug contact for 144 hrs, IC5=0.01 μM |
|
| HEK293 cells |
Cytotoxicity assay |
|
72 h |
Cytotoxicity against HEK293 cells after 72 hrs by MTT assay, IC50=0.01 μM |
|
| MKN45 cells |
Cytotoxicity assay |
|
144 h |
Cytotoxicity against human MKN45 cancer cell line was determined after 144 hr, IC50=0.012 μM |
|
| MES-SA cells |
Cytotoxicity assay |
|
72 h |
Cytotoxicity against human MES-SA cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay, IC50=0.012 μM |
|
| FM3 cells |
Proliferation assay |
|
72 h |
Antiproliferative activity against human FM3 cells after 72 hrs by MTT assay, IC50=0.013 μM |
|
| human HCT116 cells |
Cytotoxicity assay |
|
72 h |
Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay, IC50=0.022 μM |
|
| human HCT116 cells |
Proliferation assay |
|
72 h |
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay, IC50=0.025 μM |
|
| NCI-H460 cells |
Cytotoxicity assay |
|
48 h |
Cytotoxicity against human NCI-H460 cells after 48 hrs by resazurin dye assay, EC50=0.03 μM |
|
| CCRF-CEM cells |
Cytotoxicity assay |
|
48 h |
Cytotoxicity against human CCRF-CEM cells assessed as cell viability after 48 hrs by celltiter-blue assay, IC50=0.036 μM |
|
| HeLa cells |
Proliferation assay |
|
72 h |
Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay, IC50=0.044 μM |
|
| NCI60 cells |
Function assay |
|
48 h |
Antitumor activity against human NCI60 cells after 48 hrs by SRB assay, GI50=47.86 nM |
|
| MES-SA/Dx5 cells |
Proliferation assay |
|
72 h |
Antiproliferative activity against human MES-SA/Dx5 cells after 72 hrs by MTT assay, IC50=0.073 μM |
|
| SF268 cells |
Proliferation assay |
|
48 h |
Antiproliferative activity against human SF268 cells after 48 hrs, EC50=0.32 μM |
|
| KB/HeLa cells |
Proliferation assay |
|
48 h |
Antiproliferative activity against human KB/HeLa cells after 48 hrs, EC50=0.36 μM |
|
| K562 cells |
Growth inhibition assay |
|
72 h |
Growth inhibition of human K562 cells after 72 hrs by MTS method, IC50=0.42 μM |
|
| MDA-MB-231 cells |
Proliferation assay |
|
72 h |
Antiproliferative activity against human MDA-MB-231 cells by WST-1 method after 72 hrs, IC50=0.96 μM |
|
| SF268 cells |
Cytotoxicity assay |
|
48 h |
Cytotoxicity against human SF268 cells after 48 hrs by SRB assay, GI50=0.97 μM |
|
| HepG2 cells |
Proliferation assay |
|
48 h |
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay, IC50=11.05 μM |
|
| MDA435/LCC6 cells |
Proliferation assay |
|
|
Antiproliferative activity against MDA435/LCC6 cells by ELISA, IC50=0.35 nM |
|
| A2780-cell |
Growth inhibition assay |
|
|
Concentration required to inhibit A2780-cell growth by 50%, IC50=0.55 nM |
|
| G-361 cell |
Growth inhibition assay |
|
|
Cytotoxic potency required to inhibit G-361 cell growth by 50%, IC50=0.65 nM |
|
| CH1 cell |
Cytotoxicity assay |
|
|
Cytotoxic potency required to inhibit CH1 cell growth by 50%, IC50=2.65 nM |
|
| A549 cells |
Function assay |
|
|
Activity against A549 cancer cell line, IC50=3.1 nM |
|
| P388 cells |
Proliferation assay |
|
|
Antiproliferative activity against P388 cells by ELISA, IC50=4.3 nM |
|
| SKOV-3 cell |
Cytotoxicity assay |
|
|
Cytotoxic potency required to inhibit SKOV-3 cell growth 50%, IC50=5.3 nM |
|
| OVCAR-3 cell |
Function assay |
|
|
Antitumor activity against human ovarian OVCAR-3 cell lines, IC50=5.8 nM |
|
| MXF7 breast cell |
Function assay |
|
|
Antitumor activity against human mammary carcinoma sensitive MXF7 breast cell line, IC50=8.7 nM |
|
| MCF-7 cells |
Growth inhibition assay |
|
|
Inhibitory activity against human tumor cell line MCF-7 breast adenocarcinoma, IC50=0.02 μM |
|
| human small-cell lung cancer |
Cytotoxicity assay |
|
|
Cytotoxicity against human small-cell lung cancer (SCLC), IC50=0.02 μM |
|
| UACC375 cell |
Function assay |
|
|
Antitumor activity against human melanoma UACC375 cell line, IC50=0.048 μM |
|
| HT1080 cell |
Growth inhibition assay |
|
|
Inhibitory activity against human tumor cell line HT1080, IC50=0.066 μM |
|
| HCT116 cells |
Cytotoxicity assay |
|
|
Cytotoxicity against human HCT116 cells by MTT assay, IC50=3.96 μM |
|
| U937 cells |
Cytotoxicity assay |
|
|
Cytotoxicity against human U937 cells by MTT assay, IC50=6.2 μM |
|