Fungal

Fungal产品

  • 所有产品(113)
  • Fungal抑制剂 (107)
目录号 产品名 产品描述 文献引用 实验数据
S7418 Cycloheximide Cycloheximide (NSC-185, Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80),一种抗真菌抗生素,是一种真核生物蛋白质合成(protein synthesis)抑制剂,对体内蛋白质合(protein synthesis)和 RNA 合成(RNA synthesis)的 IC50 分别为 532.5 nM 和 2880 nM。Cycloheximide抑制铁死亡并抑制自噬。在溶液中不稳定,请现配现用!此产品为危化品(急性毒性/易燃/皮肤腐蚀),请在穿戴防护面罩、防护手套和防护服后使用。
Signal Transduct Target Ther, 2024, 9(1):65
Bioact Mater, 2024, 32:277-291
Nat Commun, 2024, 15(1):1282
S2476 Itraconazole Itraconazole是一种三唑类抗真菌药物,是CYP3A4的有效抑制剂,IC50为6.1 nM。Itraconazole 是一个有效的Hedgehog (Hh)信号通路的拮抗剂。Itraconazole 可通过诱导自噬来抑制恶性胶质瘤的生长。
Front Cell Infect Microbiol, 2023, 13:1128000
Front Cell Infect Microbiol, 2023, 13:1131641
Front Cell Infect Microbiol, 2022, 12:864912
S1442 Voriconazole Voriconazole是类似于氟康唑和伊曲康唑的新型三唑衍生物,其作用是通过抑制真菌 cytochrome P-450 依赖性的,14-alpha-sterol demethylase 介导的 麦角固醇的合成。
Front Cell Infect Microbiol, 2023, 13:1131641
Front Cell Infect Microbiol, 2022, 12:864912
Front Cell Infect Microbiol, 2022, 12:1074903
S1331 Fluconazole Fluconazole是一种羊毛甾醇14 alpha去甲基化酶 抑制剂,抑制了麦角固醇的形成,用于治疗和预防浅表性和全身性真菌感染。
Front Cell Infect Microbiol, 2024, 14:1296151
Front Cell Infect Microbiol, 2023, 13:1131641
Nat Commun, 2022, 13(1):1658
S1353 Ketoconazole Ketoconazole能抑制cyclosporine oxidase(环孢素氧化酶)testosterone 6 beta-hydroxylase(睾丸素6β-羟化酶)IC50分别为0.19 mM和0.22 mM。Ketoconazole 是一种雄性激素 androgen 生物合成抑制剂。
J Med Virol, 2023, 95(6):e28856
J Med Virol, 2023, 95(6):e28856
Cell Death Dis, 2023, 14(1):64
S3073 Caspofungin (MK-0991) Acetate Caspofungin Acetate (MK-0991, L-743872)是一种脂肽类抗真菌β-1,3-glucan synthase抑制剂。
Viruses, 2023, 15(2)452
BMC Med, 2022, 20(1):359
Comput Struct Biotechnol J, 2022, 20:1077-1087
S1934 Nystatin Nystatin (Fungicidin) 是一种多烯类抗真菌剂,常常被用作oropharyngeal candidosis的局部治疗剂。
Microbiol Spectr, 2023, 10.1128/spectrum.02553-23
Nature, 2022, 603(7899):159-165
Nat Metab, 2022, 4-10:1369-1401
S4286 Anidulafungin Anidulafungin, 一种echinocandin的衍生物, 抑制glucan synthase的活性, 用作抗真菌药。
Viruses, 2023, 15(2)452
BMC Med, 2022, 20(1):359
Antiviral Res, 2021, S0166-3542(21)00178-9
S4287 Micafungin Sodium Micafungin Sodium是1,3-β-D-葡聚糖合成抑制剂,用作抗真菌的药物。
Microbiol Spectr, 2024, e0352623.
BMC Med, 2022, 20(1):359
Antiviral Res, 2021, S0166-3542(21)00178-9
S3019 Ciclopirox ethanolamine Ciclopirox ethanolamine(Ciclopirox olamine, HOE 296,Ciclopiroxolamine)作为一种铁离子螯合剂,具有广谱抗真菌作用。
Commun Biol, 2023, 6(1):402
J Clin Invest, 2022, 132(9)e152345
Redox Biol, 2022, 56:102451
S2058 Tolnaftate Tolnaftate 是一种合成的硫代氨基甲酸酯,用作抗真菌剂。
J Pers Med, 2022, 12(2)258
Hum Cell, 2022, 10.1007/s13577-022-00671-y
Hum Cell, 2021, 34(6):1911-1918
S2321 Magnolol Magnolol (NSC 293099) 是一种在Houpu magnolia (Magnolia officinalis) 树皮中发现的生物活性化合物。它能抑制TNFα诱导的NF-κB的激活。
Mol Oncol, 2022, 16(15):2823-2842
Int Immunopharmacol, 2022, 112:109242
Reprod Biol, 2021, 21(4):100567
S1725 Terbinafine Terbinafine (SF 86-327,TDT 067) 用于治疗真菌感染,可以杀死真菌或防止其生长。
Front Oncol, 2023, 13:1111570
Neurooncol Adv, 2022, 4(1):vdac018
J Cell Mol Med, 2020, 25
S1956 Miconazole Nitrate Miconazole (NSC 169434) Nitrate是一种咪唑类抗真菌剂,外用或静脉输液。
Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4
Chem Biol Interact, 2021, 343:109498
Biomol Ther (Seoul), 2020, 25
S2528 Ciclopirox Ciclopirox(HOE 296b, Penlac) 是一种合成的抗真菌药物。
Cell Death Dis, 2021, 12(12):1141
J Transl Med, 2021, 19(1):347
Int J Mol Sci, 2021, 22(15)8299
S3079 Atovaquone Atovaquone (Atavaquone)用于治疗或预防肺孢子菌肺炎,弓形虫病, 疟疾和巴贝西虫。
iScience, 2024, 27(3):109172
J Cell Biochem, 2022, 10.1002/jcb.30213
Elife, 2020, 9e56773
S1606 Clotrimazole Clotrimazole (BAY b 5097, FB 5097)是一种合成的抗真菌药物,是imidazole的广谱衍生物。
iScience, 2022, 25(11):105342
Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4
J Cell Physiol, 2020, 10.1002
S2557 Terbinafine HCl Terbinafine HCl (KWD 201,KWD 2019,TDT 067 hydrochloride)通过抑制角鲨烯环氧酶抑制了麦角固醇的合成,用作抗真菌药物。
Cell Rep Med, 2023, S2666-3791(22)00494-3
Oncogene, 2021, 10.1038/s41388-021-01934-y
J Cell Mol Med, 2020, 25
S2536 Miconazole Miconazole(Monistat,R18134) 是一种咪唑类抗真菌药物。
Nat Commun, 2024, 15(1):3068
Int J Mol Sci, 2022, 23(22)13809
Chem Biol Interact, 2021, 343:109498
S1676 Amorolfine HCl Amorolfine HCl(Ro 14-4767 HCl)是一种抗真菌药物。
Nat Commun, 2021, 12(1):652
Cell Chem Biol, 2019, 26(4):593-599
Nature, 2018, 560(7718):372-376
S4075 Zinc Pyrithione Zinc pyrithione (OM-1563)是一种抗真菌和抗细菌药物,可以通过阻断质子泵破坏膜转运。
Cell Chem Biol, 2021, S2451-9456(21)00213-0
Biol Reprod, 2019, 100(2):468-478
Cell Syst, 2017, 4(6-:600-610
S5080 Neticonazole Neticonazole (SS717) 是一种选择性的针对 exosome 形成和分泌的抑制剂。 Neticonazole具有Neticonazole的抗真菌和抗肿瘤活性。
Nat Commun, 2023, 14(1):6692
Nat Commun, 2023, 14(1):6692
Clin Transl Med, 2022, 12(9):e1037
S1517 Natamycin Natamycin (Pimaricin) 是一种天然存在的三唑类抗真菌药物。具有极少或无味道干扰。
Expert Opin Drug Deliv, 2020, 17(3):407-421
BMC Microbiol, 2020, 20(1):275
S2535 Econazole nitrate Econazole Nitrate (NSC 243115,Spectazole) 是一种咪唑类抗真菌药物。
Cell Rep Med, 2023, 4(12):101309
Int J Mol Sci, 2022, 23(22)13809
Biomol Ther (Seoul), 2020, 25
S1910 Tioconazole Tioconazole (UK-20349) 是一种抗真菌药物,IC50为1.7 μM。
J Mol Cell Biol, 2021, mjab059
Chem Biol Drug Des, 2016, 10.1111/cbdd.12872
S4120 Sulconazole Nitrate Sulconazole Nitrate(Exelderm,RS 44872) 是一种咪唑衍生物,具有广谱抗真菌活性。
Int J Mol Sci, 2022, 23(22)13809
Sci Adv, 2021, 7(36):eabf6033
S4601 Clioquinol Clioquinol (Iodochlorhydroxyquin, Chinoform) 是一种具有口服活性的、亲油性的、铜离子结合的卤代8-羟基喹啉(8-hydroxyquinoline),具有抗真菌、抗寄生物以及潜在的抗肿瘤活性。
Cancer Lett, 2024, 588:216797
Mol Oncol, 2021, 10.1002/1878-0261.13079
FASEB J, 2019, 10.1096/fj.201802603RR
S5373 Pseudolaric Acid B Pseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties.
Toxicology, 2023, 493:153556
Eur J Pharmacol, 2020, 876:173064
S1666 Flucytosine (5-Fluorocytosine) Flucytosine (5-Fluorocytosine)是氟嘧啶类似物, 是抗菌药,作用于人白色念珠菌(C. albicans)时 IC50 为0.12 μg/mL。
Sci Adv, 2021, 7(27)eabh3032
S1854 Bifonazole Bifonazole (Bay h 4502,(±)-bifonazole) 是一种抗真菌剂和前列腺芳香化酶抑制剂,IC50为1.6 μM。
Nature, 2018, 560(7718):372-376
S3161 Sertaconazole nitrate Sertaconazole nitrate (FI-7045,FI7056)是一种外用广谱抗真菌药,是用来治疗表面皮肤和粘膜感染的辅助用药
Int J Mol Sci, 2022, 23(22)13809
S5359 Butoconazole Ethyl chrysanthemate is an allelochemical compound used as an attractant.
Arch Biochem Biophys, 2024, 754:109958
Nature, 2018, 560(7718):372-376
S8095 Tubercidin Tubercidin (7-deaza-adenosine),腺苷类似物,是一种核苷抗生素。它可掺入到DNA中,抑制聚合酶,因此抑制DNA复制RNA、蛋白合成。Tubercidin还具有抗真菌和抗病毒活性。
Mol Cell, 2020, 80(6):1104-1122.e9
S4584 Butylparaben Butylparaben (Butyl parahydroxybenzoate, Butyl 4-hydroxybenzoate) 是一种常在化妆品中被用作抗菌防腐剂的化合物。
Environ Toxicol, 2018, 33(4):436-445
S4178 Climbazole Climbazole(BAY-e 6975)是一种广谱的咪唑类抗真菌药剂,具有抗头皮屑的效果。
Sci Adv, 2022, 8(49):eadd2191
S3646 Thimerosal Thimerosal (Thiomersalate, Mercurothiolate) is a well-established antiseptic and antifungal agent and usually used as a preservative in vaccines, immunoglobulin preparations, skin test antigens, antivenins, ophthalmic and nasal products, and tattoo inks. This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
J Invest Dermatol, 2024, S0022-202X(23)03210-4
Cell Chem Biol, 2021, S2451-9456(21)00442-6
S4187 Salicylanilide Salicylanilides (WR10019,2-Hydroxybenzanilide)是一组具有广泛的生物活性的化合物,具有抗病毒效力,抗菌(包括抗分枝杆菌),和抗真菌活性。
Hum Mol Genet, 2020, ddaa244
S9057 Sinigrin Sinigrin (Allylglucosinolate, 2-Propenylglucosinolate) is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects.
J Invest Dermatol, 2018, 138(12):2644-2652
S5033 Terconazole Terconazole (Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol,R42470)是一种新型的、广谱的、三唑抗真菌试剂,主要用于治疗阴道真菌感染。
bioRxiv, 2020, 2020/9/20.4.7.30734
S5174 Kojic acid Kojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives.
Int J Mol Sci, 2017, 18(9)
S3722 Isavuconazole Isavuconazole (BAL-4815, RO-0094815) 是新型超广谱三唑类化合物,对酵母、霉菌和双态性真菌具有活性,抑制cytochrome P450 (CYP)依赖性的14α-lanosterol脱甲基作用,以此抑制真菌细胞膜麦角固醇的合成。
J Pharm Sci, 2023, 10.1016/j.xphs.2023.11.005
S5083 Lentinan Lentinan (A823605, Bromoduline),分离纯化自香菇子实体水煮提取物,是一种真菌多糖免疫调制剂,具有抗肿瘤活性。
Iran J Basic Med Sci, 2023, 26(7):836-842
S4878 Neticonazole Hydrochloride Neticonazole是咪唑类抗真菌剂,用于治疗皮肤真菌感染。
Clin Transl Med, 2022, 12(9):e1037
S5512 Juglone Juglone (Regianin, 5-Hydroxy-1,4-naphthoquinone)是一种天然萘醌,存在于黑核桃等植物中,对多种植物具有中等的抗真菌活性和促生长作用。它有时可以用作除草剂,作为布料和油墨的染料,以及作为食品和化妆品的着色剂。在溶液中不稳定,请现配现用!
Chin Med, 2024, 19(1):52
Nat Commun, 2019, 10(1):4013
S1997 Liranaftate Liranaftate(M-732,Piritetrate) 是一种角鲨烯环氧酶抑制剂具有抗真菌活性。
Cell Rep, 2024, 43(4):114094
S2031 Fenticonazole Nitrate Fenticonazole Nitrate(Lomexin,REC 15-1476,Falvin) 是一种唑类抗真菌药物。
S3154 Butenafine HCl Butenafine HCl (KP-363)是一种合成的苄胺类抗真菌药物,通过抑制甾醇合成,通过抑制角鲨烯环氧酶,而发挥作用。
S3156 Naftifine HCl Naftifine HCl(AW 105-843)是一种烯丙基胺类抗真菌药,外用治疗足癣,股癣,体癣,通过抑制角鲨烯2,3-环氧酶选择性抑制甾醇的生物合成。
Clin Transl Med, 2024, 14(2):e1586
Arch Biochem Biophys, 2024, 754:109958
S1833 Butoconazole nitrate Butoconazole nitrate (RS-35887)是一种抗真菌剂,抑制PHA刺激下人外周血淋巴细胞中细胞因子(如IL-2, TNFα, IFN 和 GM-CSF)的分泌,IC50分别为7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL 和 7.6 μg/mL。
S4806 Potassium 1-Naphthaleneacetate Potassium 1-Naphthaleneacetate (KANU, α-Naphthaleneacetic Acid Potassium Salt) is being studied as a synthetic growth factor that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fungal plant pathogens.
E3040 Stemonae Extract Stemonae Extract从百部Radix Stemonae的根茎中提取,作为一种口服镇咳药,在中医中已有几千年的历史,具有镇咳、抗结核、抗菌、抗真菌、抗寄生虫等药理作用。
S9200 Pneumocandin B0 Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent.
S0917 Allosecurinin Allosecurinine (Phyllochrysine) 是一种从 M.indicaM.discoidea 分离的具有抗真菌活性的Securinega生物碱。
S6254 Hydrocinnamic acid Hydrocinnamic acid (3-phenylpropionic acid, Benzylacetic acid)是苯丙氨酸代谢途径中氧化还原酶的底物。它是一种抗真菌剂和代谢物。
S4581 Triacetin Triacetin (Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane) 是一种甘油三酸酯,具有杀真菌作用。
S5213 Piroctone Olamine Piroctone Olamine (piroctone ethanolamine) is a wide spectrum antibacterial and antifungal agent used in the treatment of dandruff,fungal infections.
S5553 Kasugamycin hydrochloride Kasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species.
S0938 Sakuranetin Sakuranetin belongs to the group of methoxylated flavanones, with a widely bioactivity of antiproliferative against human cell lines typical for B16BL6 melanoma, esophageal squamous cell carcinoma (ESCC) and colon cancer (Colo 320), antiviral activity towards human rhinovirus 3 and influenza B virus, antioxidant, antimicrobial, antiinflammatory, antiparasitic, antimutagenic, and antiallergic properties.
E3071 Malaytea Scurfpea Extract Malaytea Scurfpea Extract是从补骨脂Psoralea corylifolia L.中提取的,具有抗真菌活性,对病原体具有防御作用。
S5944 Butenafine Butenafine是合成的苄胺抗真菌剂。
S3966 Nifuratel Nifuratel is a nitrofuran derivative with local antiprotozoal and antifungal activity and a broad spectrum of antibacterial action.
S3307 Galangin 3-methyl ether Galangin 3-methyl ether (3-O-Methylgalangin, 3-Methylgalangin) 分离自 Lychnophora markgravii 的地上部分,具有很强的抗细菌和抗真菌作用。
S4970 Nerol Nerol (Cis-Geraniol, Neryl alcohol)是存在于多种香精油如柠檬草和槐花中的单萜化合物。
S4862 Squalene Squalene (Spinacene, Supraene, trans-Squalene),自然存在于植物、动物和人体中,是一种添加在疫苗中佐剂,用于增强免疫反应。
S3829 Isoalantolactone Isoalantolactone, one of the major sesquiterpene lactone compounds, is isolated from the roots of Anula helenium and possesses multiple biological activities including antifungal, anthelmintic, antimicrobial, anti-inflammatory, antitrypanosomal activities and antiproliferative effects on several cancer cell lines, such as colon, melanoma, ovary, prostate, lung, and leukemia.
S0770 Camalexin Camalexin 是从亚麻荠和拟南芥(十字花科)中分离得到的一种植物抗毒素,能诱导活性氧(ROS)产生。Camalexin具有抗菌、抗真菌、抗增殖和抗癌活性。
S6118 Terpinen-4-ol Terpinen-4-ol是一种天然存在的单萜,是茶树油的主要活性成分,具有多种生物活性如抗真菌活性。
S4996 Tavaborole (AN-2690)
S5271 Suloctidil Suloctidil, a sulfur-containing aminoalcohol showing to inhibit human platelet aggregation, is a peripheral vasodilator and a potential antifungal agent.
E3725 Sapindus saponaria Linnaeus nutshell Extract (40%) Sapindus Saponaria Linnaeus Nutshell Extract (40%)提取自无患子Sapindus saponaria L.,具有抗真菌活性。
E3726 Sapindus saponaria Linnaeus nutshell Extract (70%) Sapindus Saponaria Linnaeus Nutshell Extract (70%)提取自无患子Sapindus saponaria L.,具有抗真菌活性。
S4755 lanosterol Lanosterol是一种四环三萜,它可由所有的动物、真菌类固醇衍生而来。
S3532 AN-2718 AN-2718是一种真菌生长(fungal growth)抑制剂,通过oxaborole tRNA捕获(OBORT)机制阻断蛋白合成。
S3778 Patchouli alcohol Patchouli alcohol (Patchoulol, Patchouli camphor), an ingredient in pogostemonis herba, has various pharmacological activities and acts as an inhibitor of asexual fungal propagation, inflammation, the influenza virus, and tumorigenesis.
S4963 Purpurin Purpurin (1,2,4-Trihydroxyanthraquinone, Hydroxylizaric acid, Verantin)是从茜草根和其他茜草科植物家族中分离出的天然色素。它具有抗血管生成、抗菌、抗氧化活性。Purpurin 可有效地抑制CYP1A1、CYP1A2 和 CYP1B1。
S6270 2-Aminoisobutyric acid 2-Aminoisobutyric acid (NSC-16590, 2-Methylalanine, H-Aib-OH)是一种稀有的、非蛋白氨基酸,是嘧啶代谢的终产物,随着尿液排出,在一些真菌来源的抗生素中有发现。
S3676 Carbendazim Carbendazim (Mercarzole, Carbendazole) is a broad-spectrum systemic antimycotic and can be used to control a broad range of diseases on field crops, fruits, and vegetables, including sclerotinia rot of canola, wheat head blight, peanut leaf spot, and SB on rice. Its mode of action is to inhibit the formation of mitotic microtubules in of fungi.
S4258 Luliconazole Luliconazole(NND 502)是一种广谱抗真菌药物。
Arch Biochem Biophys, 2024, 754:109958
S9350 Ethyl 4-Methoxycinnamate Ethyl 4-Methoxycinnamate (Ethyl p-methoxycinnamate, 4-Methoxycinnamic Acid Ethyl Ester), a natural product found in K. galanga and C. zedoaria extracts, has anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities.
S2534 Isoconazole nitrate Isoconazole nitrate(Travogen,Adestan G 100, R 15454) 是一种唑类抗真菌药物。
S5704 Myclobutanil Myclobutanil is a widely used triazole fungicide and also a steroid demethylation inhibitor.
S3705 Chlorobutanol Chlorobutanol (Chlorbutol, Chloreton, Chloretone, Chlortran|, trichloro-2-methyl-2-propanol)是一种防腐剂、镇静剂、催眠剂和弱的局部麻醉剂,具有抗菌抑菌作用。
S1991 iKIX1 iKIX1是一种抗真菌药物,可在体外使耐药的光念珠菌对唑类抗真菌药物重新敏感;iKIX1抑制CgGal11A的KIX结构域与CgPdr1的活化结构域相互作用,IC50和Ki值分别为190.2 μM和18 μM。
S3860 Allicin Allicin (Diallyl Thiosulfinate), the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects.
S9072 Sweroside Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects.
S6408 Hexetidine Hexetidine是一种抗细菌和抗真菌剂,具有局部麻醉、止血、除臭、预防牙菌斑作用。
S5025 Efinaconazole Efinaconazole (KP-103) 是14 alpha-demethylase的抑制剂。14 alpha-demethylase参与ergosterol的生物合成,ergosterol是真菌细胞膜的成分之一。
S3588 Hexylene glycol Hexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) 是一种衍生自丙酮的氧化溶剂,已广泛用于工业化学品和化妆品中。Hexylene glycol 具有抗菌 antibacterial 和抗真菌 antifungal 的特性。
S3595 D-Gluconic acid D-Gluconic acid 是一种抗真菌 antifungal 药。
S9413 Yangonin Yangonin (Y100550) is a dienolide kavalactone originally found in Piper methysticum (kava plant) and exhibits neuroprotective, neuromodulatory, and antifungal activities. It activates cannabinoid (CB1) receptors and potentiates the effects of GABA-A receptors.
E3706 Cortex pseudolaricis Extract Cortex Pseudolaricis Extract来自Pseudolarix amabilis Rehder的根皮,其中部分成分具有抗真菌活性、抗癌活性和过氧化物酶体增殖物激活受体活性等生物活性。
S5724 Dichlorophen Dichlorophen (Dichlorophene, Bis(5-chloro-2-hydroxyphenyl)methane) is an anticestodal agent, fungicide, germicide, and antimicrobial agent.
S5829 Monomyristin Monomyristin (Glyceryl myristate, 2,3-Dihydroxypropyl tetradecanoate)具有抗细菌和抗真菌活性。
S6451 Salifungin Salifungin (Multifungin, Bromosalicylchloranilide)是一种抗真菌剂,在某些个体中可能导致过敏性接触性皮炎。
S5541 Dimetridazole Dimetridazole is an anti-fungal and anti-protozoal used for the control of infection in pigs, poultry, turkeys, game birds, pigeons and other caged birds.
S3979 Zinc Undecylenate Zinc Undecylenate (Zinc diundec-10-enoate, Zinc 10-undecenoate) is a natural or synthetic fungistatic fatty acid, antifungal Zinc Undecylenate is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions.
S5086 p-Anisaldehyde p-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde),茴芹种子提取物,具有抗真菌活性,对很多酵母和实验室培养基、果泥和果汁中的霉菌菌株具有活性。
S6467 Fosfluconazole Fosfluconazole是一种水溶性的fluconazole盐酸盐前体药物。Fluconazole是三唑抗真菌药物,用于治疗和组织表面的和系统性真菌感染。
S9444 Tomatine Tomatine (Lycopersicin) is a natural glycoalkaloid with fungicidal, antimicrobial, and insecticidal properties.
S4525 Ethylparaben Ethylparaben (Ethyl parahydroxybenzoate, Ethyl 4-hydroxybenzoate)是对羟基苯甲酸(p-hydroxybenzoic acid)的乙酯形式,被用作抗真菌防腐剂和食品添加剂。它还是一种化学过敏原,其生理效应是通过增加组胺释放和细胞所介导的免疫反应所实现。
S4781 Xanthoxyline Xanthoxylin (Brevifolin), isolated from Zanthoxylum piperitum (Japanese pepper tree) and Sapium sebiferum (Chinese tallowtree), is a cytotoxic and fungicidal compound with the characteristics of a typical phytoalexin.
S5845 Chalcone Chalcone (benzylideneacetophenone, phenyl styryl ketone, benzalacetophenone, β-phenylacrylophenone)是一种芳族酮,是很多重要的生物化合物(chalcones)的中心,具有抗菌、抗肿瘤和消炎活性。
S4793 Cedryl acetate Cedryl Acetate (Cedrol acetate, Cedranyl acetate), an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity.
E3772 Eyebright Extract Eyebright Extract是从玄参科的小米草Herba Euphrasiae中提取的,具有抗炎、抗氧化、抗菌、抗癌、抗真菌、抗病毒、降压、保护皮肤、抗癫痫、抗卡他等活性。
E3488 Fucus vesiculosis Extract Fucus Vesiculosis Extract是从具有抗真菌特性的墨角藻Fucus vesiculosus中提取的。
S4516 (+)-Camphor Camphor是一种蜡质的、易燃的、白色或透明的固体,有强烈的香味,通常用于缓解疼痛、减少瘙痒以及治疗真菌感染。它能够激活TRPV1TRPV3
S4843 Potassium acetate Potassium acetate (Diuretic salt, Potassium ethanoate) is the potassium salt of acetic acid, which is a synthetic carboxylic acid with antibacterial and antifungal properties.
E4002New Potassium D-gluconate Potassium D-gluconate(Potassium Gluconate)是一种具有口服活性的氧化羧酸,具有防腐和螯合特性。
S3910 4',7-Dimethoxyisoflavone 4',7-Dimethoxyisoflavone, isolated from the leaves of Albizzia lebbeck, shows antifungal activity in vitro.
S4559 Cloxiquine Cloxiquine (5-Chloro-8-quinolinol, Dermofungin)是一种抗细菌、抗真菌、抗衰老和抗痨药物。
S3985 Methyl 4-hydroxybenzoate Methyl 4-hydroxybenzoate (Methylparaben, Methyl p-hydroxybenzoate, Nipagin) 是一种抗真菌剂,应用于多种化妆品、个人护理用品和食品防腐剂。
S0491 Manogepix (E1210) Manogepix (E1210, MGX, APX001A) 是一种广谱的、口服活性的抗真菌剂,可抑制 Gwt1/Gwt1p (GPI锚定壁转移蛋白1),该蛋白在真菌细胞壁完整性中起重要作用。
S3990 Trans-Anethole Trans-anethole (4-Propenylanisole)是苯丙烯衍生物,存在于多种香精油、包括茴香油中。它具有神经调节、抗焦虑、抗氧化、抗真菌、抗炎症和免疫调节活性。
S7418 Cycloheximide Cycloheximide (NSC-185, Actidione, Naramycin A, CHX, FT 3422-2, NM-MCD 80),一种抗真菌抗生素,是一种真核生物蛋白质合成(protein synthesis)抑制剂,对体内蛋白质合(protein synthesis)和 RNA 合成(RNA synthesis)的 IC50 分别为 532.5 nM 和 2880 nM。Cycloheximide抑制铁死亡并抑制自噬。在溶液中不稳定,请现配现用!此产品为危化品(急性毒性/易燃/皮肤腐蚀),请在穿戴防护面罩、防护手套和防护服后使用。
Signal Transduct Target Ther, 2024, 9(1):65
Bioact Mater, 2024, 32:277-291
Nat Commun, 2024, 15(1):1282
S2476 Itraconazole Itraconazole是一种三唑类抗真菌药物,是CYP3A4的有效抑制剂,IC50为6.1 nM。Itraconazole 是一个有效的Hedgehog (Hh)信号通路的拮抗剂。Itraconazole 可通过诱导自噬来抑制恶性胶质瘤的生长。
Front Cell Infect Microbiol, 2023, 13:1128000
Front Cell Infect Microbiol, 2023, 13:1131641
Front Cell Infect Microbiol, 2022, 12:864912
S1331 Fluconazole Fluconazole是一种羊毛甾醇14 alpha去甲基化酶 抑制剂,抑制了麦角固醇的形成,用于治疗和预防浅表性和全身性真菌感染。
Front Cell Infect Microbiol, 2024, 14:1296151
Front Cell Infect Microbiol, 2023, 13:1131641
Nat Commun, 2022, 13(1):1658
S1353 Ketoconazole Ketoconazole能抑制cyclosporine oxidase(环孢素氧化酶)testosterone 6 beta-hydroxylase(睾丸素6β-羟化酶)IC50分别为0.19 mM和0.22 mM。Ketoconazole 是一种雄性激素 androgen 生物合成抑制剂。
J Med Virol, 2023, 95(6):e28856
J Med Virol, 2023, 95(6):e28856
Cell Death Dis, 2023, 14(1):64
S3073 Caspofungin (MK-0991) Acetate Caspofungin Acetate (MK-0991, L-743872)是一种脂肽类抗真菌β-1,3-glucan synthase抑制剂。
Viruses, 2023, 15(2)452
BMC Med, 2022, 20(1):359
Comput Struct Biotechnol J, 2022, 20:1077-1087
S1934 Nystatin Nystatin (Fungicidin) 是一种多烯类抗真菌剂,常常被用作oropharyngeal candidosis的局部治疗剂。
Microbiol Spectr, 2023, 10.1128/spectrum.02553-23
Nature, 2022, 603(7899):159-165
Nat Metab, 2022, 4-10:1369-1401
S4286 Anidulafungin Anidulafungin, 一种echinocandin的衍生物, 抑制glucan synthase的活性, 用作抗真菌药。
Viruses, 2023, 15(2)452
BMC Med, 2022, 20(1):359
Antiviral Res, 2021, S0166-3542(21)00178-9
S4287 Micafungin Sodium Micafungin Sodium是1,3-β-D-葡聚糖合成抑制剂,用作抗真菌的药物。
Microbiol Spectr, 2024, e0352623.
BMC Med, 2022, 20(1):359
Antiviral Res, 2021, S0166-3542(21)00178-9
S3019 Ciclopirox ethanolamine Ciclopirox ethanolamine(Ciclopirox olamine, HOE 296,Ciclopiroxolamine)作为一种铁离子螯合剂,具有广谱抗真菌作用。
Commun Biol, 2023, 6(1):402
J Clin Invest, 2022, 132(9)e152345
Redox Biol, 2022, 56:102451
S2058 Tolnaftate Tolnaftate 是一种合成的硫代氨基甲酸酯,用作抗真菌剂。
J Pers Med, 2022, 12(2)258
Hum Cell, 2022, 10.1007/s13577-022-00671-y
Hum Cell, 2021, 34(6):1911-1918
S2321 Magnolol Magnolol (NSC 293099) 是一种在Houpu magnolia (Magnolia officinalis) 树皮中发现的生物活性化合物。它能抑制TNFα诱导的NF-κB的激活。
Mol Oncol, 2022, 16(15):2823-2842
Int Immunopharmacol, 2022, 112:109242
Reprod Biol, 2021, 21(4):100567
S1725 Terbinafine Terbinafine (SF 86-327,TDT 067) 用于治疗真菌感染,可以杀死真菌或防止其生长。
Front Oncol, 2023, 13:1111570
Neurooncol Adv, 2022, 4(1):vdac018
J Cell Mol Med, 2020, 25
S1956 Miconazole Nitrate Miconazole (NSC 169434) Nitrate是一种咪唑类抗真菌剂,外用或静脉输液。
Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4
Chem Biol Interact, 2021, 343:109498
Biomol Ther (Seoul), 2020, 25
S2528 Ciclopirox Ciclopirox(HOE 296b, Penlac) 是一种合成的抗真菌药物。
Cell Death Dis, 2021, 12(12):1141
J Transl Med, 2021, 19(1):347
Int J Mol Sci, 2021, 22(15)8299
S3079 Atovaquone Atovaquone (Atavaquone)用于治疗或预防肺孢子菌肺炎,弓形虫病, 疟疾和巴贝西虫。
iScience, 2024, 27(3):109172
J Cell Biochem, 2022, 10.1002/jcb.30213
Elife, 2020, 9e56773
S1606 Clotrimazole Clotrimazole (BAY b 5097, FB 5097)是一种合成的抗真菌药物,是imidazole的广谱衍生物。
iScience, 2022, 25(11):105342
Nat Biotechnol, 2021, 10.1038/s41587-021-00860-4
J Cell Physiol, 2020, 10.1002
S2557 Terbinafine HCl Terbinafine HCl (KWD 201,KWD 2019,TDT 067 hydrochloride)通过抑制角鲨烯环氧酶抑制了麦角固醇的合成,用作抗真菌药物。
Cell Rep Med, 2023, S2666-3791(22)00494-3
Oncogene, 2021, 10.1038/s41388-021-01934-y
J Cell Mol Med, 2020, 25
S2536 Miconazole Miconazole(Monistat,R18134) 是一种咪唑类抗真菌药物。
Nat Commun, 2024, 15(1):3068
Int J Mol Sci, 2022, 23(22)13809
Chem Biol Interact, 2021, 343:109498
S1676 Amorolfine HCl Amorolfine HCl(Ro 14-4767 HCl)是一种抗真菌药物。
Nat Commun, 2021, 12(1):652
Cell Chem Biol, 2019, 26(4):593-599
Nature, 2018, 560(7718):372-376
S4075 Zinc Pyrithione Zinc pyrithione (OM-1563)是一种抗真菌和抗细菌药物,可以通过阻断质子泵破坏膜转运。
Cell Chem Biol, 2021, S2451-9456(21)00213-0
Biol Reprod, 2019, 100(2):468-478
Cell Syst, 2017, 4(6-:600-610
S5080 Neticonazole Neticonazole (SS717) 是一种选择性的针对 exosome 形成和分泌的抑制剂。 Neticonazole具有Neticonazole的抗真菌和抗肿瘤活性。
Nat Commun, 2023, 14(1):6692
Nat Commun, 2023, 14(1):6692
Clin Transl Med, 2022, 12(9):e1037
S1517 Natamycin Natamycin (Pimaricin) 是一种天然存在的三唑类抗真菌药物。具有极少或无味道干扰。
Expert Opin Drug Deliv, 2020, 17(3):407-421
BMC Microbiol, 2020, 20(1):275
S2535 Econazole nitrate Econazole Nitrate (NSC 243115,Spectazole) 是一种咪唑类抗真菌药物。
Cell Rep Med, 2023, 4(12):101309
Int J Mol Sci, 2022, 23(22)13809
Biomol Ther (Seoul), 2020, 25
S1910 Tioconazole Tioconazole (UK-20349) 是一种抗真菌药物,IC50为1.7 μM。
J Mol Cell Biol, 2021, mjab059
Chem Biol Drug Des, 2016, 10.1111/cbdd.12872
S4120 Sulconazole Nitrate Sulconazole Nitrate(Exelderm,RS 44872) 是一种咪唑衍生物,具有广谱抗真菌活性。
Int J Mol Sci, 2022, 23(22)13809
Sci Adv, 2021, 7(36):eabf6033
S4601 Clioquinol Clioquinol (Iodochlorhydroxyquin, Chinoform) 是一种具有口服活性的、亲油性的、铜离子结合的卤代8-羟基喹啉(8-hydroxyquinoline),具有抗真菌、抗寄生物以及潜在的抗肿瘤活性。
Cancer Lett, 2024, 588:216797
Mol Oncol, 2021, 10.1002/1878-0261.13079
FASEB J, 2019, 10.1096/fj.201802603RR
S5373 Pseudolaric Acid B Pseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties.
Toxicology, 2023, 493:153556
Eur J Pharmacol, 2020, 876:173064
S1666 Flucytosine (5-Fluorocytosine) Flucytosine (5-Fluorocytosine)是氟嘧啶类似物, 是抗菌药,作用于人白色念珠菌(C. albicans)时 IC50 为0.12 μg/mL。
Sci Adv, 2021, 7(27)eabh3032
S1854 Bifonazole Bifonazole (Bay h 4502,(±)-bifonazole) 是一种抗真菌剂和前列腺芳香化酶抑制剂,IC50为1.6 μM。
Nature, 2018, 560(7718):372-376
S3161 Sertaconazole nitrate Sertaconazole nitrate (FI-7045,FI7056)是一种外用广谱抗真菌药,是用来治疗表面皮肤和粘膜感染的辅助用药
Int J Mol Sci, 2022, 23(22)13809
S5359 Butoconazole Ethyl chrysanthemate is an allelochemical compound used as an attractant.
Arch Biochem Biophys, 2024, 754:109958
Nature, 2018, 560(7718):372-376
S8095 Tubercidin Tubercidin (7-deaza-adenosine),腺苷类似物,是一种核苷抗生素。它可掺入到DNA中,抑制聚合酶,因此抑制DNA复制RNA、蛋白合成。Tubercidin还具有抗真菌和抗病毒活性。
Mol Cell, 2020, 80(6):1104-1122.e9
S4584 Butylparaben Butylparaben (Butyl parahydroxybenzoate, Butyl 4-hydroxybenzoate) 是一种常在化妆品中被用作抗菌防腐剂的化合物。
Environ Toxicol, 2018, 33(4):436-445
S4178 Climbazole Climbazole(BAY-e 6975)是一种广谱的咪唑类抗真菌药剂,具有抗头皮屑的效果。
Sci Adv, 2022, 8(49):eadd2191
S3646 Thimerosal Thimerosal (Thiomersalate, Mercurothiolate) is a well-established antiseptic and antifungal agent and usually used as a preservative in vaccines, immunoglobulin preparations, skin test antigens, antivenins, ophthalmic and nasal products, and tattoo inks. This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
J Invest Dermatol, 2024, S0022-202X(23)03210-4
Cell Chem Biol, 2021, S2451-9456(21)00442-6
S4187 Salicylanilide Salicylanilides (WR10019,2-Hydroxybenzanilide)是一组具有广泛的生物活性的化合物,具有抗病毒效力,抗菌(包括抗分枝杆菌),和抗真菌活性。
Hum Mol Genet, 2020, ddaa244
S9057 Sinigrin Sinigrin (Allylglucosinolate, 2-Propenylglucosinolate) is a glucosinolate found in some plants of the Brassicaceae family and exerts various activities including anticancer, anti-inflammatory, antibacterial, antifungal, antioxidant, and wound healing effects.
J Invest Dermatol, 2018, 138(12):2644-2652
S5033 Terconazole Terconazole (Terazol 3, Terazol 7, Triaconazole, Gyno-Terazol,R42470)是一种新型的、广谱的、三唑抗真菌试剂,主要用于治疗阴道真菌感染。
bioRxiv, 2020, 2020/9/20.4.7.30734
S3722 Isavuconazole Isavuconazole (BAL-4815, RO-0094815) 是新型超广谱三唑类化合物,对酵母、霉菌和双态性真菌具有活性,抑制cytochrome P450 (CYP)依赖性的14α-lanosterol脱甲基作用,以此抑制真菌细胞膜麦角固醇的合成。
J Pharm Sci, 2023, 10.1016/j.xphs.2023.11.005
S4878 Neticonazole Hydrochloride Neticonazole是咪唑类抗真菌剂,用于治疗皮肤真菌感染。
Clin Transl Med, 2022, 12(9):e1037
S5512 Juglone Juglone (Regianin, 5-Hydroxy-1,4-naphthoquinone)是一种天然萘醌,存在于黑核桃等植物中,对多种植物具有中等的抗真菌活性和促生长作用。它有时可以用作除草剂,作为布料和油墨的染料,以及作为食品和化妆品的着色剂。在溶液中不稳定,请现配现用!
Chin Med, 2024, 19(1):52
Nat Commun, 2019, 10(1):4013
S1997 Liranaftate Liranaftate(M-732,Piritetrate) 是一种角鲨烯环氧酶抑制剂具有抗真菌活性。
Cell Rep, 2024, 43(4):114094
S2031 Fenticonazole Nitrate Fenticonazole Nitrate(Lomexin,REC 15-1476,Falvin) 是一种唑类抗真菌药物。
S3154 Butenafine HCl Butenafine HCl (KP-363)是一种合成的苄胺类抗真菌药物,通过抑制甾醇合成,通过抑制角鲨烯环氧酶,而发挥作用。
S3156 Naftifine HCl Naftifine HCl(AW 105-843)是一种烯丙基胺类抗真菌药,外用治疗足癣,股癣,体癣,通过抑制角鲨烯2,3-环氧酶选择性抑制甾醇的生物合成。
Clin Transl Med, 2024, 14(2):e1586
Arch Biochem Biophys, 2024, 754:109958
S1833 Butoconazole nitrate Butoconazole nitrate (RS-35887)是一种抗真菌剂,抑制PHA刺激下人外周血淋巴细胞中细胞因子(如IL-2, TNFα, IFN 和 GM-CSF)的分泌,IC50分别为7.2 μg/mL, 14.4 μg/mL, 7.36 μg/mL 和 7.6 μg/mL。
S4806 Potassium 1-Naphthaleneacetate Potassium 1-Naphthaleneacetate (KANU, α-Naphthaleneacetic Acid Potassium Salt) is being studied as a synthetic growth factor that affects conidial germination, sporulation, mycelial growth, cell surface morphology, and the viability of certain fungal plant pathogens.
E3040 Stemonae Extract Stemonae Extract从百部Radix Stemonae的根茎中提取,作为一种口服镇咳药,在中医中已有几千年的历史,具有镇咳、抗结核、抗菌、抗真菌、抗寄生虫等药理作用。
S9200 Pneumocandin B0 Pneumocandin B0 (L-688786) is a natural product and a key intermediate in the synthesis of the antifungal agent.
S0917 Allosecurinin Allosecurinine (Phyllochrysine) 是一种从 M.indicaM.discoidea 分离的具有抗真菌活性的Securinega生物碱。
S6254 Hydrocinnamic acid Hydrocinnamic acid (3-phenylpropionic acid, Benzylacetic acid)是苯丙氨酸代谢途径中氧化还原酶的底物。它是一种抗真菌剂和代谢物。
S4581 Triacetin Triacetin (Glycerol triacetate, Glyceryl triacetate, Glycerin triacetate, 1,2,3-Triacetoxypropane) 是一种甘油三酸酯,具有杀真菌作用。
S5213 Piroctone Olamine Piroctone Olamine (piroctone ethanolamine) is a wide spectrum antibacterial and antifungal agent used in the treatment of dandruff,fungal infections.
S5553 Kasugamycin hydrochloride Kasugamycin is an aminoglycosidic antibiotic isolated from Streptomyces kasugaensis, showing broad-spectrum anti-fungal activity against yeast and various fungus species.
S0938 Sakuranetin Sakuranetin belongs to the group of methoxylated flavanones, with a widely bioactivity of antiproliferative against human cell lines typical for B16BL6 melanoma, esophageal squamous cell carcinoma (ESCC) and colon cancer (Colo 320), antiviral activity towards human rhinovirus 3 and influenza B virus, antioxidant, antimicrobial, antiinflammatory, antiparasitic, antimutagenic, and antiallergic properties.
E3071 Malaytea Scurfpea Extract Malaytea Scurfpea Extract是从补骨脂Psoralea corylifolia L.中提取的,具有抗真菌活性,对病原体具有防御作用。
S5944 Butenafine Butenafine是合成的苄胺抗真菌剂。
S3966 Nifuratel Nifuratel is a nitrofuran derivative with local antiprotozoal and antifungal activity and a broad spectrum of antibacterial action.
S3307 Galangin 3-methyl ether Galangin 3-methyl ether (3-O-Methylgalangin, 3-Methylgalangin) 分离自 Lychnophora markgravii 的地上部分,具有很强的抗细菌和抗真菌作用。
S4970 Nerol Nerol (Cis-Geraniol, Neryl alcohol)是存在于多种香精油如柠檬草和槐花中的单萜化合物。
S3829 Isoalantolactone Isoalantolactone, one of the major sesquiterpene lactone compounds, is isolated from the roots of Anula helenium and possesses multiple biological activities including antifungal, anthelmintic, antimicrobial, anti-inflammatory, antitrypanosomal activities and antiproliferative effects on several cancer cell lines, such as colon, melanoma, ovary, prostate, lung, and leukemia.
S0770 Camalexin Camalexin 是从亚麻荠和拟南芥(十字花科)中分离得到的一种植物抗毒素,能诱导活性氧(ROS)产生。Camalexin具有抗菌、抗真菌、抗增殖和抗癌活性。
S6118 Terpinen-4-ol Terpinen-4-ol是一种天然存在的单萜,是茶树油的主要活性成分,具有多种生物活性如抗真菌活性。
S4996 Tavaborole (AN-2690)
S5271 Suloctidil Suloctidil, a sulfur-containing aminoalcohol showing to inhibit human platelet aggregation, is a peripheral vasodilator and a potential antifungal agent.
E3725 Sapindus saponaria Linnaeus nutshell Extract (40%) Sapindus Saponaria Linnaeus Nutshell Extract (40%)提取自无患子Sapindus saponaria L.,具有抗真菌活性。
E3726 Sapindus saponaria Linnaeus nutshell Extract (70%) Sapindus Saponaria Linnaeus Nutshell Extract (70%)提取自无患子Sapindus saponaria L.,具有抗真菌活性。
S4755 lanosterol Lanosterol是一种四环三萜,它可由所有的动物、真菌类固醇衍生而来。
S3532 AN-2718 AN-2718是一种真菌生长(fungal growth)抑制剂,通过oxaborole tRNA捕获(OBORT)机制阻断蛋白合成。
S3778 Patchouli alcohol Patchouli alcohol (Patchoulol, Patchouli camphor), an ingredient in pogostemonis herba, has various pharmacological activities and acts as an inhibitor of asexual fungal propagation, inflammation, the influenza virus, and tumorigenesis.
S4963 Purpurin Purpurin (1,2,4-Trihydroxyanthraquinone, Hydroxylizaric acid, Verantin)是从茜草根和其他茜草科植物家族中分离出的天然色素。它具有抗血管生成、抗菌、抗氧化活性。Purpurin 可有效地抑制CYP1A1、CYP1A2 和 CYP1B1。
S6270 2-Aminoisobutyric acid 2-Aminoisobutyric acid (NSC-16590, 2-Methylalanine, H-Aib-OH)是一种稀有的、非蛋白氨基酸,是嘧啶代谢的终产物,随着尿液排出,在一些真菌来源的抗生素中有发现。
S3676 Carbendazim Carbendazim (Mercarzole, Carbendazole) is a broad-spectrum systemic antimycotic and can be used to control a broad range of diseases on field crops, fruits, and vegetables, including sclerotinia rot of canola, wheat head blight, peanut leaf spot, and SB on rice. Its mode of action is to inhibit the formation of mitotic microtubules in of fungi.
S4258 Luliconazole Luliconazole(NND 502)是一种广谱抗真菌药物。
Arch Biochem Biophys, 2024, 754:109958
S9350 Ethyl 4-Methoxycinnamate Ethyl 4-Methoxycinnamate (Ethyl p-methoxycinnamate, 4-Methoxycinnamic Acid Ethyl Ester), a natural product found in K. galanga and C. zedoaria extracts, has anti-inflammatory, antiangiogenic, antifungal, larvicidal, and analgesic activities.
S2534 Isoconazole nitrate Isoconazole nitrate(Travogen,Adestan G 100, R 15454) 是一种唑类抗真菌药物。
S5704 Myclobutanil Myclobutanil is a widely used triazole fungicide and also a steroid demethylation inhibitor.
S3705 Chlorobutanol Chlorobutanol (Chlorbutol, Chloreton, Chloretone, Chlortran|, trichloro-2-methyl-2-propanol)是一种防腐剂、镇静剂、催眠剂和弱的局部麻醉剂,具有抗菌抑菌作用。
S1991 iKIX1 iKIX1是一种抗真菌药物,可在体外使耐药的光念珠菌对唑类抗真菌药物重新敏感;iKIX1抑制CgGal11A的KIX结构域与CgPdr1的活化结构域相互作用,IC50和Ki值分别为190.2 μM和18 μM。
S3860 Allicin Allicin (Diallyl Thiosulfinate), the main biologically active component of the freshly crushed garlic extracts, possesses various biological activities including antibacterial, antifungal and antiparasitic effects.
S9072 Sweroside Sweroside, a bioactive herbal ingredient isolated from Fructus Corni, exhibits diverse biological activities, such as anti-fungal, anti-diabetic, anti-inflammatory, and anti-tumor effects.
S6408 Hexetidine Hexetidine是一种抗细菌和抗真菌剂,具有局部麻醉、止血、除臭、预防牙菌斑作用。
S5025 Efinaconazole Efinaconazole (KP-103) 是14 alpha-demethylase的抑制剂。14 alpha-demethylase参与ergosterol的生物合成,ergosterol是真菌细胞膜的成分之一。
S3588 Hexylene glycol Hexylene glycol (HG, 2-Methyl-2,4-pentanediol, MPD) 是一种衍生自丙酮的氧化溶剂,已广泛用于工业化学品和化妆品中。Hexylene glycol 具有抗菌 antibacterial 和抗真菌 antifungal 的特性。
S3595 D-Gluconic acid D-Gluconic acid 是一种抗真菌 antifungal 药。
S9413 Yangonin Yangonin (Y100550) is a dienolide kavalactone originally found in Piper methysticum (kava plant) and exhibits neuroprotective, neuromodulatory, and antifungal activities. It activates cannabinoid (CB1) receptors and potentiates the effects of GABA-A receptors.
E3706 Cortex pseudolaricis Extract Cortex Pseudolaricis Extract来自Pseudolarix amabilis Rehder的根皮,其中部分成分具有抗真菌活性、抗癌活性和过氧化物酶体增殖物激活受体活性等生物活性。
S5724 Dichlorophen Dichlorophen (Dichlorophene, Bis(5-chloro-2-hydroxyphenyl)methane) is an anticestodal agent, fungicide, germicide, and antimicrobial agent.
S5829 Monomyristin Monomyristin (Glyceryl myristate, 2,3-Dihydroxypropyl tetradecanoate)具有抗细菌和抗真菌活性。
S6451 Salifungin Salifungin (Multifungin, Bromosalicylchloranilide)是一种抗真菌剂,在某些个体中可能导致过敏性接触性皮炎。
S5541 Dimetridazole Dimetridazole is an anti-fungal and anti-protozoal used for the control of infection in pigs, poultry, turkeys, game birds, pigeons and other caged birds.
S3979 Zinc Undecylenate Zinc Undecylenate (Zinc diundec-10-enoate, Zinc 10-undecenoate) is a natural or synthetic fungistatic fatty acid, antifungal Zinc Undecylenate is used topically in creams against fungal infections, eczemas, ringworm, and other cutaneous conditions.
S5086 p-Anisaldehyde p-Anisaldehyde (4-Methoxybenzaldehyde, Anisaldehyde, Anisic aldehyde, P-Methoxybenzaldehyde, 4-Anisaldehyde),茴芹种子提取物,具有抗真菌活性,对很多酵母和实验室培养基、果泥和果汁中的霉菌菌株具有活性。
S6467 Fosfluconazole Fosfluconazole是一种水溶性的fluconazole盐酸盐前体药物。Fluconazole是三唑抗真菌药物,用于治疗和组织表面的和系统性真菌感染。
S9444 Tomatine Tomatine (Lycopersicin) is a natural glycoalkaloid with fungicidal, antimicrobial, and insecticidal properties.
S4525 Ethylparaben Ethylparaben (Ethyl parahydroxybenzoate, Ethyl 4-hydroxybenzoate)是对羟基苯甲酸(p-hydroxybenzoic acid)的乙酯形式,被用作抗真菌防腐剂和食品添加剂。它还是一种化学过敏原,其生理效应是通过增加组胺释放和细胞所介导的免疫反应所实现。
S5845 Chalcone Chalcone (benzylideneacetophenone, phenyl styryl ketone, benzalacetophenone, β-phenylacrylophenone)是一种芳族酮,是很多重要的生物化合物(chalcones)的中心,具有抗菌、抗肿瘤和消炎活性。
S4793 Cedryl acetate Cedryl Acetate (Cedrol acetate, Cedranyl acetate), an acetylated from cedarwood oil, has been applied to chemistry for its properties as a chiral and cell signaling reagent with antifungal and immunotoxicity functions. Cedryl acetate exhibits α-glucosidase inhibitory activity.
E3772 Eyebright Extract Eyebright Extract是从玄参科的小米草Herba Euphrasiae中提取的,具有抗炎、抗氧化、抗菌、抗癌、抗真菌、抗病毒、降压、保护皮肤、抗癫痫、抗卡他等活性。
E3488 Fucus vesiculosis Extract Fucus Vesiculosis Extract是从具有抗真菌特性的墨角藻Fucus vesiculosus中提取的。
S4516 (+)-Camphor Camphor是一种蜡质的、易燃的、白色或透明的固体,有强烈的香味,通常用于缓解疼痛、减少瘙痒以及治疗真菌感染。它能够激活TRPV1TRPV3
S4843 Potassium acetate Potassium acetate (Diuretic salt, Potassium ethanoate) is the potassium salt of acetic acid, which is a synthetic carboxylic acid with antibacterial and antifungal properties.
S3910 4',7-Dimethoxyisoflavone 4',7-Dimethoxyisoflavone, isolated from the leaves of Albizzia lebbeck, shows antifungal activity in vitro.
S4559 Cloxiquine Cloxiquine (5-Chloro-8-quinolinol, Dermofungin)是一种抗细菌、抗真菌、抗衰老和抗痨药物。
S3985 Methyl 4-hydroxybenzoate Methyl 4-hydroxybenzoate (Methylparaben, Methyl p-hydroxybenzoate, Nipagin) 是一种抗真菌剂,应用于多种化妆品、个人护理用品和食品防腐剂。
S0491 Manogepix (E1210) Manogepix (E1210, MGX, APX001A) 是一种广谱的、口服活性的抗真菌剂,可抑制 Gwt1/Gwt1p (GPI锚定壁转移蛋白1),该蛋白在真菌细胞壁完整性中起重要作用。
S3990 Trans-Anethole Trans-anethole (4-Propenylanisole)是苯丙烯衍生物,存在于多种香精油、包括茴香油中。它具有神经调节、抗焦虑、抗氧化、抗真菌、抗炎症和免疫调节活性。
E4002New Potassium D-gluconate Potassium D-gluconate(Potassium Gluconate)是一种具有口服活性的氧化羧酸,具有防腐和螯合特性。

Fungal抑制剂选择性比较

Tags: Fungal inhibitor|Fungal agonist|Fungal activator|Fungal inducer|Fungal antagonist|Fungal signaling pathway|Fungal assay kit
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