肺癌

肺癌亚型

非小细胞肺癌

鳞状上皮细胞癌

腺癌

大细胞肺癌

小细胞肺癌

小细胞肺癌

化疗

铂类

Nedaplatin

Cisplatin

Carboplatin

Lobaplatin

生物碱类

Nab-Paclitaxel

Vinorelbine ditartrate

Paclitaxel

Docetaxel

抗代谢类

Pemetrexed

Gemcitabine

Methotrexate

拓扑异构酶抑制剂

Irinotecan

Etoposide

Topotecan

Doxorubicin

烷化剂

TMZ

Ifosfamide

Cyclophosphamide

免疫检查点抑制剂

PD-1

Cemiplimab

Pembrolizumab

Camrelizumab

Sintilimab

Nivolumab

Serplulimab

PD-L1

Avelumab

Atezolizumab

Durvalumab

Adebrelimab

Sugemalimab

Cosibelimab

CTLA-4

Ipilimumab

Tremelimumab

靶向-KRAS G12C

ADC/PROTAC

c-Met

Telisotuzumab vedotin

HER3

Patritumab deruxtecan

HER2

Trastuzumab-deruxtecan

Trastuzumab-Emtansine

TROP2

Sacituzumab-govitecan

Datopotamab deruxtecan

EGFR

Cetuximab-MMAE

ALK

MS4078

CEACAM5

Tusamitamab ravtansine

ROR2

Ozuriftamab vedotin

靶向-HER2

Pan-HER TKIs

Afatinib

Neratinib

Dacomitinib

选择性HER2 TKIs

Pyrotinib dimaleate

Poziotinib

Sunvozertinib

Anti-HER2单抗

Trastuzumab

Pertuzumab

靶向-ALK

一代ALK-TKIs ^[1]

Crizotinib

二代ALK-TKIs ^[1]

Ceritinib

Alectinib

Brigatinib

Ensartinib dihydrochloride

三代ALK-TKIs ^[1]

Lorlatinib 

靶向-EGFR

一代EGFR-TKIs ^[2]

Erlotinib

Gefitinib

Lapatinib

Icotinib

二代EGFR-TKIs ^[2]

Afatinib

Dacomitinib

Neratinib

Poziotinib

三代EGFR-TKIs ^{[3] [4]}

Osimertinib

Mobocertinib

Rociletinib

Olmutinib

Nazartinib

Alflutinib mesylate

Almonertinib

Lazertinib

四代EGFR-TKIs ^[3]

EAI045

BLU-945

CH7233163

TQB3804

Anti-EGFR单抗

Cetuximab

Panitumumab

Necitumumab

抗血管生成

靶向-MET

I型MET-TKIs ^[5]

Crizotinib

Capmatinib

Tepotinib

Savolitinib

II型MET-TKIs ^[5]

Cabozantinib

Merestinib

III型MET-TKIs ^[5]

Tivantinib

靶向-ROS1

一代ROS1-TKIs ^[6]

Crizotinib

二代ROS1-TKIs ^[6]

Ceritinib

Repotrectinib

三代ROS1-TKIs ^[6]

Lorlatinib 

靶向-BRAF

一代(I型)BRAF抑制剂 ^[7]

Vemurafenib

Dabrafenib

Encorafenib

二代(I型)BRAF抑制剂 ^[7]

AZ 628

LY3009120

Belvarafenib

CCT196969

Tovorafenib

Naporafenib

PLX7904

PLX8394

靶向-RET

选择性RET抑制剂

Selpercatinib

Pralsetinib

非选择性RET抑制剂

Cabozantinib

Vandetanib

Lenvatinib

Regorafenib

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