Bevacizumab (anti-VEGF)
别名: rhuMab VEGF 中文名称：贝伐珠单抗，贝伐单抗
Bevacizumab (anti-VEGF, Avastin) 是一种人源化的anti-VEGF单克隆抗体，是VEGF的抑制剂。可与所有人源VEGF-A亚型（和具有生物活性的蛋白水解片段）结合、中和。MW:149 KD。
点击购买Bevacizumab (anti-VEGF)的同型对照：
客户使用Selleck的Bevacizumab (anti-VEGF)发表文献41篇
产品质控
批次：
纯度：
99.4%
蛋白浓度： 5mg/ml
内毒素： ≤1 EU/mg
99.4
VEGFR抑制剂选择性比较
| 抑制剂名称 | 引文数量 | VEGFR1 | VEGFR2 | VEGFR3 | 其他靶点 |
|---|---|---|---|---|---|
| Sorafenib tosylate | 265 | Raf-1,B-Raf,B-Raf (V599E) | |||
| Sunitinib malate | 165 | FLT3,Kit,PDGFRβ | |||
| Cabozantinib (XL184) | 156 | c-Met | |||
| Ponatinib | 210 | Abl,PDGFRα,FGFR1 | |||
| Axitinib | 179 | PDGFRβ,Kit,PDGFRα | |||
| Foretinib | 93 | Met,Tie-2,RON | |||
| Vandetanib | 108 | EGFR | |||
| Nintedanib | 142 | LCK,FLT3,FGFR2 | |||
| Regorafenib | 197 | RET,Raf-1,Kit | |||
| Pazopanib HCl | 55 | FGFR,PDGFR,c-Kit | |||
| Cediranib (AZD2171) | 66 | c-Kit,PDGFRβ,FGFR1 | |||
| PD173074 | 120 | FGFR1 | |||
| Dovitinib (TKI-258) | 49 | FLT3,c-Kit,FGFR1 | |||
| Linifanib (ABT-869) | 32 | CSF-1R,FLT3,Kit | |||
| Vatalanib (PTK787) 2HCl | 51 | PDGFRβ,c-Kit,c-Fms | |||
| RAF265 (CHIR-265) | 23 | B-Raf | |||
| Tivozanib | 38 | EphB2,PDGFRα,PDGFRβ | |||
| Motesanib Diphosphate (AMG-706) | 12 | Kit,RET,PDGFR | |||
| Lenvatinib | 115 | PDGFRβ,FGFR1,PDGFRα | |||
| Brivanib (BMS-540215) | 9 | FGFR1 | |||
| MGCD-265 analog | 12 | Met,RON,Tie-2 | |||
| AEE788 (NVP-AEE788) | 13 | EGFR,HER2/ErbB2,c-Abl | |||
| ENMD-2076 | 8 | FLT3,RET,Aurora A | |||
| OSI-930 | 7 | CSF-1R,LCK,C-Raf | |||
| CYC116 | 10 | Aurora A,Aurora B,FLT3 | |||
| Ki8751 | 20 | c-Kit,PDGFRα | |||
| Telatinib | 5 | c-Kit,PDGFRα | |||
| Pazopanib | 78 | c-Kit,PDGFR,FGFR | |||
| KRN 633 | 6 | PDGFRα,c-Kit,BTK | |||
| SAR131675 | 30 | ||||
| Apatinib (YN968D1) mesylate | 23 | RET | |||
| BMS-794833 | 1 | Met | |||
| Cabozantinib malate | 104 | c-Met | |||
| Brivanib Alaninate (BMS-582664) | 2 | FGFR1 | |||
| Golvatinib (E7050) | 8 | c-Met | |||
| Semaxanib (SU5416) | 19 | ||||
| ZM 323881 HCl | 17 | ||||
| ZM 306416 | 13 | Src,Abl | |||
| ENMD-2076 L-(+)-Tartaric acid | 0 | FLT3,RET,Aurora A | |||
| Sitravatinib (MGCD516) | 3 | DDR2,EPHA3,Axl | |||
| BFH772 | 0 | ||||
| BAW2881 (NVP-BAW2881) | 2 | C-Raf-1,B-RAFV599E,c-Abl | |||
| SU5402 | 17 | FGFR1,PDGFRβ | |||
| Sunitinib | 231 | c-Kit,FLT3 ,PDGFRβ | |||
| Dovitinib (TKI258) Lactate monohydrate | 30 | FLT3,c-Kit,FGFR1 | |||
| LY2874455 | 14 | FGFR2,FGFR1,FGFR4 | |||
| SKLB1002 | 4 | ||||
| AZD2932 | 3 | PDGFRβ,Flt3,c-Kit |
点击展开更多
1. 鼠标悬停在“+”上可以显示相关IC50的具体数值。"+"越多，抑制作用越强。2. "✔"表示该化合物对相应的亚型有抑制作用，但抑制强度暂时没有相关数据。
生物活性
| 产品描述 | Bevacizumab (anti-VEGF, Avastin) 是一种人源化的anti-VEGF单克隆抗体，是VEGF的抑制剂。可与所有人源VEGF-A亚型（和具有生物活性的蛋白水解片段）结合、中和。MW:149 KD。 | |||
|---|---|---|---|---|
| 靶点 |
|
抗体信息
| CAS号 | 216974-75-3 |
|---|---|
| 配制 | PBS buffer, pH 7.2 |
| 推荐同型对照 | Human IgG1 |
| 来源 | CHO cells |
| 储存条件(自收到货起) | Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
常见克隆号文献对比
*Selleck收集了市面上此靶点抗体的常见克隆号，并调查了这些克隆在文献中的使用情况（数据截至2024年9月)。结果显示，Selleck选择的克隆号更广泛被使用。
技术支持
如果有其他问题，请给我们留言。
* 必填项
常见问题及建议解决方法
问题 1:
How to store the antibody?
回答：
Store the undiluted solution at 4 °C in the dark. Freezing antibodies can result in a loss of activity caused by the freezing/thawing process. Diluting antibodies to working concentrations and storing at 4°C for more than a day should be avoided. Additionally, make sure to keep the antibody sterile. Under these storage conditions, your antibodies should remain active for up to one year and oftentimes longer.
