代谢

肿瘤糖酵解 ^[1]

GLUTs抑制剂

WZB117

BAY-876

STF-31

DRB18

Phloretin

HKII抑制剂

2-DG

Lonidamine

Bromopyruvic acid

PFKFB3抑制剂

PFK15

3PO

PFK158

KAN0438757

PKM2抑制剂

PKM2 inhibitor

Shikonin

Alkannin

LDHA抑制剂

Sodium oxamate

-GNE-140

GSK 2837808A

AZ-33

FX11

MCTs抑制剂

AZD3965

VB124

Syrosingopine

α-cyano-4-hydroxycinnamic acid

BAY-8002

脂代谢重编程 ^[2]

SCAP/SREBPs抑制剂

PF 429242

Fatostatin

Cinobufotalin

Betulin

他汀类

Simvastatin

Pitavastatin calcium

Lovastatin

SLC25A1抑制剂

CTPI-2

ACLY抑制剂

BMS303141

Bempedoic acid

NDI-091143

ACSS2抑制剂

Firsocostat

TOFA

ND646

FASN抑制剂

Denifanstat

C75

TVB-3166

Orlistat

SCD1抑制剂

A939572

MF-438

LXR/ABCA1激动剂

GW3965 HCl

LXR-623

SR9243

CPT1抑制剂

Etomoxir sodium salt

Perhexiline maleate

谷氨酰胺代谢 ^[3]

GLS1/2抑制剂

Telaglenastat

BPTES

GK921

Glutamine耗竭

4-PBA

ASCT2/SLC1A5抑制剂

V-9302

GPNA

Glutamine拮抗剂

JHU-083

6-Diazo-5-oxo-L-norleucine

JHU395

GDH抑制剂

EGCG

R162

-Epicatechin gallate

GW5074

Bithionol

Aminotransferase抑制剂

AOA hemihydrochloride

线粒体代谢 ^[4]

IDH抑制剂

Ivosidenib

Enasidenib

AGI-6780

Vorasidenib

Olutasidenib

IDH-305

AGI-5198

AG-120

BAY 1436032

SDH抑制剂

3-Nitropropionic acid

Ethyl potassium malonate

SOD模拟物

Mito-TEMPO

EUK 134

Deacetylasperulosidic acid

TET1/2抑制剂

Bobcat339 hydrochloride

Disodium -2-Hydroxyglutarate

L-2-Hydroxyglutaric acid disodium

KGDH抑制剂

Devimistat

4-Methyl-2-oxovaleric acid

PDH抑制剂

DCA

Devimistat

KPLH1130

OXPHOS抑制剂

IACS-010759

Oligomycin A

FCCP

CCCP

Lixumistat

肠道微生物代谢 ^[5]

脂类

Lipopolysaccharides

Cholesterol

Sphingosine

短链脂肪酸

Sodium butyrate

L-Lactic acid

2-Methylpentanoic acid

Spinach Extract

3-Methylbutanoic acid

Oxalic acid

Sodium propionate

胆汁酸

Lithocholic acid

Cholic acid

Chenodeoxycholic Acid

Hyodeoxycholic acid

胆碱代谢物

Betaine

Trimethylamine N-oxide dihydrate

N-Methylsarcosine

Dimethylamine hydrochloride

Methylamine hydrochloride

维生素

Vitamin K2

Biotin

Folic acid

Thiamine HCl

Riboflavin

Pyridoxine

D-Pantothenate Sodium

核苷酸代谢 ^[6]

DHODH抑制剂

Leflunomide

Teriflunomide

Brequinar

Orludodstat

TS抑制剂

Pemetrexed disodium

5-FU

Raltitrexed

Folinic acid

Pemetrexed

TAS-102

DHFR抑制剂

Pemetrexed disodium

Methotrexate

Pralatrexate

Pyrimethamine

IMPDH1/2抑制剂

Mycophenolic acid

Mizoribine

Merimepodib

RNR抑制剂

Hydroxyurea

Gemcitabine

Clofarabine

Triapine

精氨酸代谢 ^[7]

PRMT5抑制剂

EPZ015666

Pemrametostat

LLY-283

GSK591

Onametostat

PAD4抑制剂

Cl-amidine

GSK484 HCl

BMS-P5

ODC抑制剂

Eflornithine hydrochloride hydrate

ASS1抑制剂

Cisplatin

Arginase抑制剂

Nor-NOHA acetate

Polymyxin B sulphate

L-Norvaline

BEC HCl

色氨酸代谢 ^[7]

IDO/TDO抑制剂

Epacadostat

Indoximod

Navoximod

Linrodostat

IDO-IN-2

IDO inhibitor 1

PF-06840003

LM10

680C91

AHR抑制剂

PD98059

CH-223191

SR1

BAY-218

BAY 2416964

GNF351

GCN2抑制剂

GCN2iB

丝氨酸&甘氨酸代谢 ^[7]

PHGDH抑制剂

NCT-503

CBR-5884

SHMT2抑制剂

SIS17

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